Protein: TKT
Transketolase (TK) (EC 2.2.1.1)

Gene: TKT
Organism: Homo sapiens
Interactions: 228
UniProt ID: P29401

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004802 - transketolase activity
GO:0005509 - calcium ion binding
GO:0005654 - nucleoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

346013

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.656

High

666837

TKT
Transketolase

1

12

Small-scale

0.647

High

496376

TAU
Microtubule-associated protein tau

2

7

High-throughput

0.628

High

666856

MK08
Mitogen-activated protein kinase 8

2

3

High-throughput

0.628

High

666984

E2AK4
eIF-2-alpha kinase GCN2

2

1

High-throughput

0.628

High

666867

TKTL1
Transketolase-like protein 1

1

12

High-throughput

0.618

High

226604

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.611

High

336375

SODC
Superoxide dismutase [Cu-Zn]

2

1

High-throughput

0.611

High

60299

POTEF
POTE ankyrin domain family member F

2

0

High-throughput

0.602

High

666897

TRI32
E3 ubiquitin-protein ligase TRIM32

2

0

High-throughput

0.602

High

666902

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

0

High-throughput

0.602

High

666907

DPOA2
DNA polymerase alpha subunit B

2

0

High-throughput

0.602

High

666913

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.602

High

666918

GREB1
Protein GREB1

2

0

High-throughput

0.602

High

666940

SMG8
Nonsense-mediated mRNA decay factor SMG8

2

0

High-throughput

0.602

High

666948

ATG2B
Autophagy-related protein 2 homolog B

2

0

High-throughput

0.602

High

666971

WDR54
WD repeat-containing protein 54

2

0

High-throughput

0.602

High

666979

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

High-throughput

0.602

High

666996

TPPC8
Trafficking protein particle complex subunit 8

2

0

High-throughput

0.602

High

528607

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.601

High

243983

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

397802

ISG15
Ubiquitin-like protein ISG15

2

5

High-throughput

0.584

High

487162

ANDR
Androgen receptor

2

2

High-throughput

0.584

High

666853

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

666893

DMWD
Dystrophia myotonica WD repeat-containing protein

2

3

High-throughput

0.574

High

666942

WDR19
WD repeat-containing protein 19

2

3

High-throughput

0.574

High

666972

WDR41
WD repeat-containing protein 41

2

3

High-throughput

0.574

High

666921

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

High-throughput

0.571

High

666938

NHLC2
NHL repeat-containing protein 2

2

0

High-throughput

0.559

High

666869

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

128456

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.536

High

170266

TIF1A
Transcription intermediary factor 1-alpha

1

4

High-throughput

0.536

High

245565

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

3

High-throughput

0.536

High

362854

FINC
Fibronectin

1

1

High-throughput

0.536

High

555308

H2AX
Histone H2AX

1

1

High-throughput

0.536

High

601138

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

High-throughput

0.536

High

666846

SOAT1
Sterol O-acyltransferase 1

1

2

High-throughput

0.536

High

666848

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

4

High-throughput

0.536

High

666855

HD
Huntingtin

1

1

High-throughput

0.536

High

666858

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

High-throughput

0.536

High

666883

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.536

High

666889

KPCZ
Protein kinase C zeta type

1

5

High-throughput

0.536

High

666890

KPCD
Protein kinase C delta type

1

5

High-throughput

0.536

High

666899

GOGA4
Golgin subfamily A member 4

1

2

High-throughput

0.536

High

666912

PLEC
Plectin

1

1

High-throughput

0.536

High

666914

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.536

High

666923

FIGL1
Fidgetin-like protein 1

1

1

High-throughput

0.536

High

666944

NEK7
Serine/threonine-protein kinase Nek7

1

6

High-throughput

0.536

High

666963

KPCD2
Serine/threonine-protein kinase D2

1

4

High-throughput

0.536

High

666991

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.518

High

201230

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

232644

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.513

High

666854

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

666891

EXOS9
Exosome complex component RRP45

1

0

High-throughput

0.513

High

666929

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.513

High

666943

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

666947

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.513

High

666951

MOCOS
Molybdenum cofactor sulfurase

1

0

High-throughput

0.513

High

666965

ATG5
Autophagy protein 5

1

0

High-throughput

0.513

High

666970

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

666973

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.513

High

666974

EMAL4
Echinoderm microtubule-associated protein-like 4

1

0

High-throughput

0.513

High

666992

INT6
Integrator complex subunit 6

1

0

High-throughput

0.513

High

667003

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

666901

SQSTM
Sequestosome-1

1

0

Small-scale

0.505

High

666882

TBA1B
Tubulin alpha-1B chain

1

2

High-throughput

0.489

High

666917

ACSF4
Beta-alanine-activating enzyme

1

1

High-throughput

0.489

High

666933

MYLK4
Myosin light chain kinase family member 4

1

4

High-throughput

0.489

High

666952

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

1

High-throughput

0.489

High

666959

MYOC
Myocilin

1

0

Small-scale

0.480

High

179558

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

199534

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

2

Small-scale

0.479

High

294414

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

322224

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

340388

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.479

High

373739

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

384332

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

391563

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

444840

ANXA5
Annexin A5

1

2

High-throughput

0.479

High

535800

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.479

High

538115

ENPL
Endoplasmin

1

5

High-throughput

0.479

High

562881

STMN1
Stathmin

1

1

High-throughput

0.479

High

569241

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

578278

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

591745

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.479

High

614249

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.479

High

617439

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

641628

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

High-throughput

0.479

High

653486

CALR
Calreticulin

1

1

High-throughput

0.479

High

666840

PDIA3
Protein disulfide-isomerase A3

1

2

High-throughput

0.479

High

666842

1433B
14-3-3 protein beta/alpha

1

5

High-throughput

0.479

High

666843

1433S
14-3-3 protein sigma

1

5

High-throughput

0.479

High

666847

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

666851

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.479

High

666857

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.479

High

666859

YAP1
Transcriptional coactivator YAP1

1

6

High-throughput

0.479

High

666862

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

666863

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

666866

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.479

High

666874

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.479

High

666875

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

666877

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.479

High

666878

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

666879

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

666880

H4
Histone H4

1

1

High-throughput

0.479

High

666881

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.479

High

666894

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

666895

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

666896

FOXC1
Forkhead box protein C1

1

2

High-throughput

0.479

High

666898

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

3

High-throughput

0.479

High

666900

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

666903

CUL3
Cullin-3

1

2

High-throughput

0.479

High

666904

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

666905

DX39B
Spliceosome RNA helicase DDX39B

1

2

High-throughput

0.479

High

666906

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

666908

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

666910

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

666911

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

666915

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.479

High

666924

BCOR
BCL-6 corepressor

1

2

High-throughput

0.479

High

666925

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

1

High-throughput

0.479

High

666934

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

666935

RPTOR
Regulatory-associated protein of mTOR

1

5

High-throughput

0.479

High

666945

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

666946

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.479

High

666949

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

666950

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

666954

CK5P2
CDK5 regulatory subunit-associated protein 2

1

4

Small-scale

0.479

High

666955

PARK7
Parkinson disease protein 7

1

2

High-throughput

0.479

High

666958

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

666961

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.479

High

666966

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

Small-scale

0.479

High

666976

ANLN
Anillin

1

1

High-throughput

0.479

High

666977

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

666982

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

666986

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.479

High

666988

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

666989

TES
Testin

1

1

High-throughput

0.479

High

666993

TRI33
E3 ubiquitin-protein ligase TRIM33

1

5

High-throughput

0.479

High

666994

HDAC5
Histone deacetylase 5

1

3

High-throughput

0.479

High

666995

NINL
Ninein-like protein

1

2

High-throughput

0.479

High

667002

RBM8A
RNA-binding protein 8A

1

3

High-throughput

0.479

High

128812

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.458

High

225538

PCDH7
Protocadherin-7

1

0

High-throughput

0.458

High

265960

PSIP1
PC4 and SFRS1-interacting protein

1

0

High-throughput

0.458

High

354311

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

386160

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

393056

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

396890

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

418887

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.458

High

430065

PROF1
Profilin-1

1

0

High-throughput

0.458

High

519128

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

536314

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.458

High

552015

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

625143

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

650441

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

666838

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

666839

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

666845

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

666850

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

666852

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

666861

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

666865

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

666868

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

666870

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

666876

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.458

High

666884

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

666885

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

666888

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

666916

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

666919

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.458

High

666922

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

666930

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

666931

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

666932

FBX11
F-box only protein 11

1

0

High-throughput

0.458

High

666937

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

666956

EYA1
Eyes absent homolog 1

1

0

High-throughput

0.458

High

666957

NECD
Necdin

1

0

High-throughput

0.458

High

666960

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

666962

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

666975

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

666978

LANC2
LanC-like protein 2

1

0

High-throughput

0.458

High

666981

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

666987

TRM7
tRNA

1

0

High-throughput

0.458

High

666998

FBX7
F-box only protein 7

1

0

Small-scale

0.458

High

666999

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

667000

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

667001

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.458

High

401477

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

666844

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

666871

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.445

High

666939

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

351722

SOMA
Somatotropin

1

1

High-throughput

0.437

High

531734

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.437

High

666887

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

4

High-throughput

0.437

High

666920

M3K19
Mitogen-activated protein kinase kinase kinase 19

1

2

High-throughput

0.437

High

666926

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

666927

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.437

High

666967

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

666968

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

666969

AKTIP
AKT-interacting protein

1

2

Small-scale

0.437

High

666983

BAHC1
BAH and coiled-coil domain-containing protein 1

1

2

High-throughput

0.437

High

666873

CD81
CD81 antigen

1

0

High-throughput

0.426

High

666892

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

666864

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

230581

KATIP
Katanin-interacting protein

1

1

High-throughput

0.407

High

666872

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

165309

KHNYN
Protein KHNYN

2

0

High-throughput

0.328

High

230466

TYW4
tRNA wybutosine-synthesizing protein 4

2

0

High-throughput

0.328

High

329399

AGR2
Anterior gradient protein 2 homolog

2

0

Small-scale

0.313

High

666841

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

666941

RN214
RING finger protein 214

1

0

High-throughput

0.279

Low

666953

CE034
Uncharacterized protein C5orf34

1

0

High-throughput

0.279

Low

666849

SPB5
Serpin B5

1

0

Small-scale

0.251

Low

239503

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

532064

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.249

Low

596461

PTMS
Parathymosin

1

0

High-throughput

0.249

Low

666860

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

666886

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

666909

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

Small-scale

0.249

Low

666928

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

666936

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

666964

ARP6
Actin-related protein 6

1

0

High-throughput

0.249

Low

666980

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

666985

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

0

High-throughput

0.249

Low

666990

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.249

Low

666997

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024