Protein: APH1
Gamma-secretase subunit Aph-1 (Presenilin-stabilization factor)

Gene: APH1, aph-1
Organism: Drosophila melanogaster
Interactions: 17
UniProt ID: Q9VQG2

Gene Ontology (top 5):
GO:0005770 - late endosome
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0006509 - membrane protein ectodomain proteolysis
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

145769

PSN
Presenilin homolog

2

10

Small-scale

0.754

High

1285555

PEN2
Gamma-secretase subunit pen-2

2

3

Small-scale

0.584

High

1469861

NICA
Nicastrin

2

6

Small-scale

0.584

High

1261801

Q7JRF1
RE48509p

2

0

High-throughput

0.569

High

1343416

Q8SWV5
LD47995p

2

0

High-throughput

0.569

High

1230966

Q6AWN6
GEO12823p1

1

1

High-throughput

0.494

High

1262077

Q7JV09
GH28348p

1

1

High-throughput

0.481

High

1484188

Q9W3F3
RH03540p

1

1

High-throughput

0.451

High

98502

F0JAP7
LP18071p

1

1

High-throughput

0.439

High

356995

U729
UPF0729 protein CG18508

2

0

High-throughput

0.310

High

1266474

Q7K4J7
LD36653p

2

0

High-throughput

0.310

High

1343766

Q8SXH7
GEO09915p1

2

0

High-throughput

0.310

High

1345642

Q8T3P5
AT26438p

2

0

High-throughput

0.310

High

1478606

Q9VJP1
AT05822p

2

0

High-throughput

0.310

High

1484187

Q9VYR9
LD34222p

2

0

High-throughput

0.310

High

1440446

Q9I7M1
Olfactory-specific 9

1

0

High-throughput

0.265

Low

1484189

Q9W465
FI21917p1

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025