Protein: FOXO
Forkhead box protein O (dFOXO) (Protein FKHR)

Gene: FOXO
Organism: Drosophila melanogaster
Interactions: 211
UniProt ID: Q95V55

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

685364

CROC
Fork head domain-containing protein crocodile

1

20

High-throughput

0.698

High

685382

FD5
Fork head domain-containing protein FD5

1

18

High-throughput

0.698

High

1279939

FOXO
Forkhead box protein O

1

17

Small-scale

0.647

High

664627

1433Z
14-3-3 protein zeta

2

20

High-throughput

0.611

High

955013

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.611

High

1212081

Q8I9J6
Histone deacetylase

1

17

Small-scale

0.561

High

114118

M9PBC6
Bub3 interacting GLEBS and zinc finger domain protein, isoform F

1

8

High-throughput

0.541

High

114245

M9PBR0
Blimp-1, isoform B

1

2

High-throughput

0.541

High

185937

PITX
Pituitary homeobox homolog Ptx1

1

20

High-throughput

0.541

High

220655

CTBP
C-terminal-binding protein

1

9

High-throughput

0.541

High

247698

CYCL
Protein cycle

1

14

High-throughput

0.541

High

367198

ANTP
Homeotic protein antennapedia

1

20

High-throughput

0.541

High

429445

SRYB
Serendipity locus protein beta

1

1

High-throughput

0.541

High

434875

SNAI
Protein snail

1

1

High-throughput

0.541

High

484954

HMH2
Homeobox protein H2.0

1

20

High-throughput

0.541

High

486712

ROUGH
Homeobox protein rough

1

20

High-throughput

0.541

High

509374

DA
Protein daughterless

1

1

High-throughput

0.541

High

611960

RUNT
Segmentation protein Runt

1

1

High-throughput

0.541

High

612425

DSX
Protein doublesex

1

10

High-throughput

0.541

High

620059

POXM
Paired box pox-meso protein

1

9

High-throughput

0.541

High

620112

POXN
Paired box pox-neuro protein

1

9

High-throughput

0.541

High

881923

COLL
Transcription factor collier

1

1

High-throughput

0.541

High

976107

HMSH
Muscle segmentation homeobox

1

20

High-throughput

0.541

High

996072

GAGA
Transcription activator GAGA

1

14

High-throughput

0.541

High

1118413

Q4V3F5
FI01110p

1

3

High-throughput

0.541

High

1178739

GLIS2
Zinc finger protein GLIS2 homolog

1

7

High-throughput

0.541

High

1180805

HEY
Hairy/enhancer-of-split related with YRPW motif protein

1

4

High-throughput

0.541

High

1214844

Q8IQJ5
Uncharacterized protein

1

20

High-throughput

0.541

High

1248275

PHO
Polycomb protein PHO

1

8

High-throughput

0.541

High

1279950

Q9VBN9
RE40275p

1

2

High-throughput

0.541

High

1279956

Q9VEF1
Uncharacterized protein

1

4

High-throughput

0.541

High

1279957

Q9VEF4
IP01257p

1

2

High-throughput

0.541

High

1279963

Q9VGL2
GM08392p

1

1

High-throughput

0.541

High

1279969

RN
Zinc finger protein rotund

1

2

High-throughput

0.541

High

1279982

Q9VQ77
LD29420p

1

3

High-throughput

0.541

High

1279984

BOWEL
Protein bowel

1

1

High-throughput

0.541

High

1279986

Q9VSC2
Extra-extra

1

20

High-throughput

0.541

High

1279993

CREBB
Cyclic AMP response element-binding protein B

1

5

High-throughput

0.541

High

1279997

Q9VYE0
Doublesex-Mab related 11E

1

10

High-throughput

0.541

High

1280012

Q9W423
LD18904p

1

1

High-throughput

0.541

High

1280018

R4GRV8
C2H2-type domain-containing protein

1

3

High-throughput

0.541

High

1280019

X2JDS9
Visual system homeobox 2

1

20

High-throughput

0.541

High

1099750

E2F1
Transcription factor E2f1

1

0

High-throughput

0.518

High

1178219

Q7JZC5
Linking immunity and metabolism

1

0

High-throughput

0.518

High

1178265

Q7JZD5
Dorsal interacting protein 3

1

0

High-throughput

0.518

High

1248982

Q8SXZ6
RE39769p

1

0

High-throughput

0.518

High

1279941

SUZ12
Polycomb protein Su(z)12

1

0

High-throughput

0.518

High

1279967

Q9VHL0
Hinge2

1

0

High-throughput

0.518

High

1213370

AKT1
RAC serine/threonine-protein kinase

1

11

Small-scale

0.501

High

1279955

Q9VDJ9
non-specific serine/threonine protein kinase

1

1

Small-scale

0.501

High

1214427

Q8IQ04
GEO11681p1

1

1

High-throughput

0.494

High

1215389

INDRA
Zinc finger protein indra

1

0

High-throughput

0.486

High

81220

B7Z045
BTB-protein-VII, isoform G

1

15

High-throughput

0.481

High

114256

M9PBS1
Earmuff, isoform B

1

2

High-throughput

0.481

High

668270

ABDA
Homeobox protein abdominal-A

1

20

High-throughput

0.481

High

950031

UBX
Homeotic protein ultrabithorax

1

20

High-throughput

0.481

High

1098022

BUN2
Protein bunched, class 2/F/G isoform

1

2

High-throughput

0.481

High

1117948

Q4QPP9
GH02096p

1

2

High-throughput

0.481

High

1182470

Q7KUL4
Intermediate neuroblasts defective

1

20

High-throughput

0.481

High

1214320

Q8IPV7
Cabut, isoform B

1

12

High-throughput

0.481

High

1279953

Q9VCB2
LD04007p

1

14

High-throughput

0.481

High

1279960

Q9VEY3
48 related 2, isoform B

1

2

High-throughput

0.481

High

1280020

X2JIB5
Uncharacterized protein, isoform D

1

2

High-throughput

0.481

High

51893

A1Z6Z7
Uncharacterized protein, isoform A

1

11

High-throughput

0.479

High

53443

A1Z8U0
Pre-mRNA processing factor 8

1

2

High-throughput

0.479

High

55169

A1ZAH8
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

55343

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

1

High-throughput

0.479

High

90507

E1JGL8
Uncharacterized protein, isoform C

1

13

High-throughput

0.479

High

185833

PAX6
Paired box protein Pax-6

1

18

Small-scale

0.479

High

218337

O44434
QKR58E-3

1

4

High-throughput

0.479

High

246673

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

247410

O61380
Eukaryotic translation initiation factor 4G1, isoform A

1

7

High-throughput

0.479

High

332812

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

20

High-throughput

0.479

High

432495

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

7

High-throughput

0.479

High

436861

KRH1
Krueppel homolog 1

1

1

Small-scale

0.479

High

501521

ACT1
Actin-5C

1

2

High-throughput

0.479

High

520040

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.479

High

578681

ARM
Armadillo segment polarity protein

1

14

Small-scale

0.479

High

580735

DDX17
ATP-dependent RNA helicase p62

1

3

High-throughput

0.479

High

589668

USP
Protein ultraspiracle

1

20

Small-scale

0.479

High

624238

MLE
Dosage compensation regulator mle

1

3

High-throughput

0.479

High

631310

BRM
ATP-dependent helicase brm

1

20

High-throughput

0.479

High

669819

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

713054

TTF2
Transcription termination factor 2

1

20

High-throughput

0.479

High

820497

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.479

High

879470

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.479

High

978461

NONA
Protein no-on-transient A

1

3

High-throughput

0.479

High

984772

HMGD
High mobility group protein D

1

20

High-throughput

0.479

High

995772

SQD
RNA-binding protein squid

1

6

High-throughput

0.479

High

1001000

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

9

High-throughput

0.479

High

1096741

RS5A
Small ribosomal subunit protein uS7A

1

1

High-throughput

0.479

High

1097629

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

20

High-throughput

0.479

High

1099156

CAF1
Chromatin assembly factor 1 p55 subunit

1

7

High-throughput

0.479

High

1152643

SARM1
NAD(+) hydrolase sarm1

1

8

High-throughput

0.479

High

1180731

Q7KLW9
Pre-mRNA-processing factor 19

1

6

High-throughput

0.479

High

1182602

Q7KV89
non-specific serine/threonine protein kinase

1

2

High-throughput

0.479

High

1212951

PANG2
Protein pangolin, isoform J

1

20

Small-scale

0.479

High

1213563

SLE
Protein slender lobes

1

5

High-throughput

0.479

High

1215204

CLSPN
Claspin

1

3

High-throughput

0.479

High

1250063

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.479

High

1279943

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

5

High-throughput

0.479

High

1279944

Q9V3E7
LD24793p

1

3

High-throughput

0.479

High

1279945

Q9V426
LD07162p

1

2

High-throughput

0.479

High

1279947

Q9VA35
CIN85 and CD2AP related, isoform A

1

1

High-throughput

0.479

High

1279948

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

1279949

LARP
La-related protein 1

1

8

High-throughput

0.479

High

1279951

Q9VBX3
Vig2, isoform B

1

2

High-throughput

0.479

High

1279959

Q9VEV1
non-specific serine/threonine protein kinase

1

10

High-throughput

0.479

High

1279964

IPO9
Importin-9

1

5

High-throughput

0.479

High

1279965

Y6693
J domain-containing protein CG6693

1

7

High-throughput

0.479

High

1279966

Q9VHC7
FI21236p1

1

3

High-throughput

0.479

High

1279970

Q9VJ86
Bicoid stability factor

1

2

High-throughput

0.479

High

1279974

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

High-throughput

0.479

High

1279979

Q9VP57
LD15904p

1

1

High-throughput

0.479

High

1279980

Q9VPL9
FI24801p1

1

20

High-throughput

0.479

High

1279988

Q9VTC1
RNA helicase

1

4

High-throughput

0.479

High

1279990

Q9VV52
LD37257p

1

16

High-throughput

0.479

High

1279999

Q9VZF5
Kinesin-like protein

1

3

High-throughput

0.479

High

1280003

Q9W0R0
Cell division cycle 5, isoform A

1

1

High-throughput

0.479

High

1280004

Q9W1I0
TAR DNA-binding protein-43 homolog, isoform A

1

9

High-throughput

0.479

High

1280006

Q9W254
Quaking related 58E-2, isoform A

1

4

High-throughput

0.479

High

1280011

Q9W414
Regulatory particle triple-A ATPase 4

1

1

High-throughput

0.479

High

1280015

Q9W4M7
Twenty-four, isoform B

1

9

High-throughput

0.479

High

1280016

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.479

High

55552

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.458

High

90637

E1JH23
Oxysterol-binding protein

1

0

High-throughput

0.458

High

116126

M9PHL6
Bifocal, isoform E

1

0

High-throughput

0.458

High

284949

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

669602

CLH
Clathrin heavy chain

1

0

High-throughput

0.458

High

771680

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.458

High

784890

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.458

High

984477

KPEL
Serine/threonine-protein kinase pelle

1

0

Small-scale

0.458

High

1001161

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

1278925

Q95RE4
LD37574p

1

0

High-throughput

0.458

High

1279952

Q9VC08
LD43724p

1

0

High-throughput

0.458

High

1279972

Q9VLC5
Aldehyde dehydrogenase

1

0

High-throughput

0.458

High

1279977

RHEB
GTP-binding protein Rheb homolog

1

0

High-throughput

0.458

High

1279989

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

1279994

Q9VX08
LD10434p

1

0

High-throughput

0.458

High

1279996

RRP12
RRP12-like protein

1

0

High-throughput

0.458

High

1280007

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.458

High

2609

A0A0B4KHC8
Sp1-like factor for pairing sensitive-silencing, isoform B

1

14

High-throughput

0.457

High

2634

A0A0B4LH09
Maf-S, isoform B

1

2

High-throughput

0.457

High

2639

A0A0B4LH78
48 related 2, isoform D

1

4

High-throughput

0.457

High

332121

O96620
Intermediate neuroblasts defective protein

1

20

High-throughput

0.457

High

1098018

BUN1
Protein bunched, class 1/class 3/D/E isoforms

1

2

High-throughput

0.457

High

1118115

Q4R0P9
Cabut

1

12

High-throughput

0.457

High

1279981

ERM
Fez family zinc finger protein erm

1

2

High-throughput

0.457

High

1280000

Q9VZU5
BTB-protein-VII, isoform F

1

20

High-throughput

0.457

High

1280014

Q9W4F9
IP01388p

1

2

High-throughput

0.457

High

1213923

Q8IPA6
RE15759p

1

1

High-throughput

0.439

High

1279942

Q9U4U5
LD16082p

1

1

High-throughput

0.439

High

56391

A1ZBW6
Uncharacterized protein, isoform A

1

3

High-throughput

0.437

High

93912

F0JAG2
MIP27703p

1

7

High-throughput

0.437

High

137492

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

4

High-throughput

0.437

High

248485

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.437

High

440972

RLA1
Large ribosomal subunit protein P1

1

2

High-throughput

0.437

High

527105

SPTCA
Spectrin alpha chain

1

3

High-throughput

0.437

High

570444

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.437

High

665710

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.437

High

803318

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.437

High

878924

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.437

High

1115257

Q494K2
Chromosome transmission fidelity 4

1

10

High-throughput

0.437

High

1129011

Q5KTT4
Eukaryotic translation initiation factor 4 gamma 2

1

3

High-throughput

0.437

High

1182585

Q7KV70
Karst, isoform C

1

2

High-throughput

0.437

High

1279946

EPB41
Protein 4.1 homolog

1

1

High-throughput

0.437

High

1279954

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

6

High-throughput

0.437

High

1279958

Q9VEH0
Aluminum tubes, isoform A

1

7

High-throughput

0.437

High

1279961

RRP15
RRP15-like protein

1

1

High-throughput

0.437

High

1279962

Q9VGH5
AT27789p

1

13

High-throughput

0.437

High

1279971

PESC
Pescadillo homolog

1

2

High-throughput

0.437

High

1279973

Y3096
Ribosomal L1 domain-containing protein CG13096

1

4

High-throughput

0.437

High

1279975

EI3F1
Eukaryotic translation initiation factor 3 subunit F-1

1

4

High-throughput

0.437

High

1279978

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.437

High

1279983

Q9VQK7
LD45152p

1

1

High-throughput

0.437

High

1279985

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.437

High

1279987

Q9VT19
RRM domain-containing protein

1

7

High-throughput

0.437

High

1279991

LUC7L
Putative RNA-binding protein Alsin2

1

2

High-throughput

0.437

High

1279995

Q9VXQ5
T-complex protein 1 subunit zeta

1

1

High-throughput

0.437

High

1280001

Q9W0A8
FI01658p

1

1

High-throughput

0.437

High

1280002

Q9W0B8
Coatomer subunit alpha

1

6

High-throughput

0.437

High

1280005

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.437

High

1280009

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.437

High

1280010

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.437

High

1213939

Q8IPA8
Uncharacterized protein, isoform E

1

2

High-throughput

0.417

High

1279940

Q9GR11
Ral guanine nucleotide dissociation stimulator-like protein

1

1

High-throughput

0.417

High

1213595

KTAP2
Protein KRTCAP2 homolog

1

0

High-throughput

0.282

High

1248337

Q8STG9
DSec61alpha

1

0

High-throughput

0.265

Low

184505

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

218114

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

0

High-throughput

0.249

Low

401218

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low

524737

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.249

Low

588696

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

0

High-throughput

0.249

Low

734336

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

780846

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.249

Low

816473

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.249

Low

842177

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.249

Low

954804

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

0

High-throughput

0.249

Low

1181727

RS19B
Small ribosomal subunit protein eS19B

1

0

High-throughput

0.249

Low

1182027

Q7KTD0
Multidrug-Resistance like protein 1, isoform D

1

0

High-throughput

0.249

Low

1182135

Q7KTL4
Septin interacting protein 2, isoform C

1

0

High-throughput

0.249

Low

1249988

Q8T3H9
AT04280p

1

0

High-throughput

0.249

Low

1279968

Q9VHV6
RE31520p

1

0

High-throughput

0.249

Low

1279976

Q9VNB9
Large ribosomal subunit protein eL33

1

0

High-throughput

0.249

Low

1279992

Q9VVU2
Large ribosomal subunit protein uL24

1

0

High-throughput

0.249

Low

1279998

Q9VZC8
GEO12024p1

1

0

High-throughput

0.249

Low

1280008

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.249

Low

1280013

Q9W4C1
IP13321p

1

0

High-throughput

0.249

Low

1280017

Q9XZ31
Anastral spindle 2, isoform A

1

0

High-throughput

0.249

Low

1098578

NETB
Netrin-B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024