Protein: ITSN2
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)

Gene: ITSN2
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q9NZM3

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339058

EGFR
Epidermal growth factor receptor

4

20

High-throughput

0.884

High

1349276

SPN90
NCK-interacting protein with SH3 domain

2

4

High-throughput

0.811

High

992496

SOS1
Son of sevenless homolog 1

2

16

High-throughput

0.791

High

476483

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

13

High-throughput

0.778

High

840840

DYN2
Dynamin-2

2

12

High-throughput

0.757

High

1020402

EPS8
Epidermal growth factor receptor kinase substrate 8

1

18

Small-scale

0.740

High

983935

KPCZ
Protein kinase C zeta type

2

9

High-throughput

0.737

High

1349279

EP15R
Epidermal growth factor receptor substrate 15-like 1

5

17

High-throughput

0.713

High

1203306

FCSD1
F-BAR and double SH3 domains protein 1

2

19

Small-scale

0.677

High

1287515

AP2M1
AP-2 complex subunit mu

3

9

High-throughput

0.667

High

790688

WASP
Actin nucleation-promoting factor WAS

2

20

Small-scale

0.633

High

135796

P3C2B
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

1

4

High-throughput

0.621

High

257713

ANR17
Ankyrin repeat domain-containing protein 17

1

3

High-throughput

0.621

High

279897

TRIO
Triple functional domain protein

1

19

High-throughput

0.621

High

298006

FCSD2
F-BAR and double SH3 domains protein 2

1

20

High-throughput

0.621

High

992521

SOS2
Son of sevenless homolog 2

1

14

High-throughput

0.621

High

1017828

STX4
Syntaxin-4

1

2

High-throughput

0.621

High

1078919

ITSN1
Intersectin-1

1

19

High-throughput

0.621

High

1285205

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.621

High

1307421

SH3G1
Endophilin-A2

1

20

High-throughput

0.621

High

1349275

ITSN2
Intersectin-2

1

18

High-throughput

0.621

High

991902

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

6

Small-scale

0.620

High

253421

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

8

Small-scale

0.618

High

508233

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

601605

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.618

High

608159

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

1349281

UBQL2
Ubiquilin-2

1

12

High-throughput

0.618

High

926031

AP2B1
AP-2 complex subunit beta

2

20

High-throughput

0.611

High

166056

SYNJ2
Synaptojanin-2

2

10

Small-scale

0.595

High

815714

TNFL6
Tumor necrosis factor ligand superfamily member 6

2

1

Small-scale

0.594

High

1056150

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.589

High

787985

EPS15
Epidermal growth factor receptor substrate 15

2

17

High-throughput

0.586

High

1070179

RABE1
Rab GTPase-binding effector protein 1

2

6

Small-scale

0.578

High

370586

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

1168427

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.553

High

1300028

LMTK3
Serine/threonine-protein kinase LMTK3

1

20

High-throughput

0.553

High

1217590

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

9

High-throughput

0.541

High

686759

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

864110

AP2S1
AP-2 complex subunit sigma

1

9

High-throughput

0.536

High

1014096

AP1B1
AP-1 complex subunit beta-1

1

20

High-throughput

0.536

High

1070670

RNPS1
RNA-binding protein with serine-rich domain 1

1

8

High-throughput

0.536

High

1160903

FXL19
F-box/LRR-repeat protein 19

1

1

High-throughput

0.536

High

1251932

RIN3
Ras and Rab interactor 3

1

13

High-throughput

0.536

High

1309721

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

14

High-throughput

0.536

High

1331810

RNF41
E3 ubiquitin-protein ligase NRDP1

1

8

High-throughput

0.536

High

1332845

GARE1
GRB2-associated and regulator of MAPK protein 1

1

3

High-throughput

0.536

High

597432

PTN
Pleiotrophin

1

0

High-throughput

0.518

High

1349278

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.518

High

1027627

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

High-throughput

0.515

High

1153063

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

1349288

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1329264

SEM6A
Semaphorin-6A

1

4

Small-scale

0.508

High

1336341

K1549
UPF0606 protein KIAA1549

1

3

Small-scale

0.508

High

197624

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

9

Small-scale

0.501

High

1016339

TBL3
Transducin beta-like protein 3

1

6

High-throughput

0.494

High

1080411

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.489

High

1317037

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.486

High

64498

GOG8A
Golgin subfamily A member 8A

1

11

High-throughput

0.481

High

126965

WASL
Actin nucleation-promoting factor WASL

1

16

High-throughput

0.481

High

145955

DLGP1
Disks large-associated protein 1

1

5

High-throughput

0.481

High

206699

WIPF1
WAS/WASL-interacting protein family member 1

1

10

High-throughput

0.481

High

264110

TACC1
Transforming acidic coiled-coil-containing protein 1

1

9

High-throughput

0.481

High

320434

SNP29
Synaptosomal-associated protein 29

1

5

High-throughput

0.481

High

344384

ANGT
Angiotensinogen

1

6

High-throughput

0.481

High

610517

CBL
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.481

High

745328

RBMX
RNA-binding motif protein, X chromosome

1

2

High-throughput

0.481

High

824471

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.481

High

827763

AMPH
Amphiphysin

1

8

High-throughput

0.481

High

904174

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

4

High-throughput

0.481

High

946759

TMF1
TATA element modulatory factor

1

4

High-throughput

0.481

High

974160

DYST
Dystonin

1

16

High-throughput

0.481

High

1035214

ROCK1
Rho-associated protein kinase 1

1

7

High-throughput

0.481

High

1059285

GOGB1
Golgin subfamily B member 1

1

10

High-throughput

0.481

High

1138331

MYOME
Myomegalin

1

7

High-throughput

0.481

High

1172834

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

4

High-throughput

0.481

High

1216165

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

10

High-throughput

0.481

High

1231806

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

2

High-throughput

0.481

High

1257321

WIPF2
WAS/WASL-interacting protein family member 2

1

9

High-throughput

0.481

High

1260413

PDC6I
Programmed cell death 6-interacting protein

1

9

High-throughput

0.481

High

1287890

REPS1
RalBP1-associated Eps domain-containing protein 1

1

17

High-throughput

0.481

High

1289566

HOOK2
Protein Hook homolog 2

1

14

High-throughput

0.481

High

1302776

RUFY1
RUN and FYVE domain-containing protein 1

1

11

High-throughput

0.481

High

1310577

LARP6
La-related protein 6

1

2

High-throughput

0.481

High

1330034

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

High-throughput

0.481

High

1349277

DAPLE
Protein Daple

1

15

High-throughput

0.481

High

1349289

WASF2
Actin-binding protein WASF2

1

6

High-throughput

0.481

High

62648

WIPF3
WAS/WASL-interacting protein family member 3

1

12

Small-scale

0.479

High

206084

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

377746

GCR
Glucocorticoid receptor

1

19

High-throughput

0.479

High

451583

CLCA
Clathrin light chain A

1

10

High-throughput

0.479

High

451745

CLCB
Clathrin light chain B

1

10

High-throughput

0.479

High

507279

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

547250

EZRI
Ezrin

1

10

High-throughput

0.479

High

591123

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

738090

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

781034

OPRD
Delta-type opioid receptor

1

1

Small-scale

0.479

High

849278

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

4

High-throughput

0.479

High

1077970

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

2

High-throughput

0.479

High

1146905

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.479

High

1199052

PABP2
Polyadenylate-binding protein 2

1

4

High-throughput

0.479

High

1242673

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

5

High-throughput

0.479

High

1256771

FBF1
Fas-binding factor 1

1

19

High-throughput

0.479

High

1259877

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

10

High-throughput

0.479

High

1288351

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

13

High-throughput

0.479

High

1291722

BICD1
Protein bicaudal D homolog 1

1

6

High-throughput

0.479

High

1336202

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

8

High-throughput

0.479

High

1347087

RBM22
Pre-mRNA-splicing factor RBM22

1

3

High-throughput

0.479

High

1349280

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1349284

MYO6
Unconventional myosin-VI

1

10

High-throughput

0.479

High

1349286

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

5

High-throughput

0.479

High

1349287

NINL
Ninein-like protein

1

9

High-throughput

0.479

High

321433

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.464

High

619834

IP3KA
Inositol-trisphosphate 3-kinase A

1

0

High-throughput

0.460

High

834361

PSN1
Presenilin-1

1

0

High-throughput

0.460

High

1060434

GPNMB
Transmembrane glycoprotein NMB

1

0

High-throughput

0.460

High

1084649

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.460

High

1136923

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.460

High

1344301

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.460

High

1349282

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

1

0

High-throughput

0.460

High

1290768

MCRS1
Microspherule protein 1

1

0

High-throughput

0.458

High

1344096

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1155937

Q6NSK7
RIN3 protein

1

11

High-throughput

0.457

High

1296147

MEG10
Multiple epidermal growth factor-like domains protein 10

1

1

Small-scale

0.457

High

581877

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.445

High

1044207

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.445

High

232554

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.439

High

308269

LC7L3
Luc7-like protein 3

1

3

High-throughput

0.439

High

568524

SYN1
Synapsin-1

1

11

High-throughput

0.439

High

833048

YLPM1
YLP motif-containing protein 1

1

4

High-throughput

0.439

High

995264

GOGA2
Golgin subfamily A member 2

1

7

High-throughput

0.439

High

1138230

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

8

High-throughput

0.439

High

1176016

GARE2
GRB2-associated and regulator of MAPK protein 2

1

19

High-throughput

0.439

High

1232662

FNBP4
Formin-binding protein 4

1

1

High-throughput

0.439

High

441383

RU2B
U2 small nuclear ribonucleoprotein B''

1

2

High-throughput

0.437

High

1188419

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.437

High

1188961

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1243166

SRFB1
Serum response factor-binding protein 1

1

1

High-throughput

0.437

High

1269784

ESR2
Estrogen receptor beta

1

19

High-throughput

0.437

High

1349285

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

1

High-throughput

0.437

High

1266810

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1316524

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.279

Low

1309445

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.251

Low

1349283

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024