Protein: GEM
GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR)

Gene: GEM
Organism: Homo sapiens
Interactions: 155
UniProt ID: P55040

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000287 - magnesium ion binding
GO:0003924 - GTPase activity
GO:0005246 - calcium channel regulator activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

874341

PDLI7
PDZ and LIM domain protein 7

4

4

High-throughput

0.799

High

874282

USH1G
pre-mRNA splicing regulator USH1G

2

6

High-throughput

0.783

High

874290

TBC3G
TBC1 domain family member 3G

2

9

High-throughput

0.783

High

874315

ASB15
Ankyrin repeat and SOCS box protein 15

2

3

High-throughput

0.783

High

874338

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

2

High-throughput

0.783

High

874352

ZRAN1
Ubiquitin thioesterase ZRANB1

2

7

High-throughput

0.783

High

734568

TRI23
E3 ubiquitin-protein ligase TRIM23

5

20

High-throughput

0.720

High

874346

GMIP
GEM-interacting protein

1

2

Small-scale

0.713

High

874304

AN36B
Ankyrin repeat domain-containing protein 36B

2

5

High-throughput

0.700

High

874337

PKHF2
Pleckstrin homology domain-containing family F member 2

2

7

High-throughput

0.700

High

874285

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

6

High-throughput

0.680

High

536765

TRI27
Zinc finger protein RFP

3

4

High-throughput

0.675

High

874271

GOGA2
Golgin subfamily A member 2

3

8

High-throughput

0.675

High

874276

TRAF1
TNF receptor-associated factor 1

3

5

High-throughput

0.675

High

874324

LZTS2
Leucine zipper putative tumor suppressor 2

3

13

High-throughput

0.675

High

874334

GO45
Golgin-45

3

1

High-throughput

0.675

High

874355

IKZF3
Zinc finger protein Aiolos

3

1

High-throughput

0.675

High

874268

Q05BL1
TP53BP2 protein

1

4

High-throughput

0.665

High

874284

RUN3A
RUN domain-containing protein 3A

1

4

High-throughput

0.662

High

874277

ASPP2
Apoptosis-stimulating of p53 protein 2

1

5

High-throughput

0.621

High

874255

KR107
Keratin-associated protein 10-7

3

5

High-throughput

0.616

High

874280

K1H1
Keratin, type I cuticular Ha1

3

9

High-throughput

0.616

High

874297

KCTD9
BTB/POZ domain-containing protein KCTD9

3

1

High-throughput

0.616

High

869910

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

2

1

High-throughput

0.615

High

683223

1433B
14-3-3 protein beta/alpha

2

18

Small-scale

0.612

High

70971

ZBT42
Zinc finger and BTB domain-containing protein 42

2

3

High-throughput

0.606

High

182411

ZSC9
Zinc finger and SCAN domain-containing protein 9

2

2

High-throughput

0.606

High

204306

MS18B
Protein Mis18-beta

2

1

High-throughput

0.606

High

235491

VINEX
Vinexin

2

5

High-throughput

0.606

High

359475

K2C6A
Keratin, type II cytoskeletal 6A

2

4

High-throughput

0.606

High

443424

VIME
Vimentin

2

7

High-throughput

0.606

High

473648

ZN688
Zinc finger protein 688

2

1

High-throughput

0.606

High

546077

MYOG
Myogenin

2

1

High-throughput

0.606

High

563395

ZNF20
Zinc finger protein 20

2

1

High-throughput

0.606

High

816235

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

2

4

High-throughput

0.606

High

874270

TLE5
TLE family member 5

2

1

High-throughput

0.606

High

874272

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

874273

TRAF2
TNF receptor-associated factor 2

2

9

High-throughput

0.606

High

874274

TRI32
E3 ubiquitin-protein ligase TRIM32

2

7

High-throughput

0.606

High

874281

INSC
Protein inscuteable homolog

2

1

High-throughput

0.606

High

874286

EFHC2
EF-hand domain-containing family member C2

2

5

High-throughput

0.606

High

874291

ZN774
Zinc finger protein 774

2

1

High-throughput

0.606

High

874293

MORN3
MORN repeat-containing protein 3

2

1

High-throughput

0.606

High

874300

TRI69
E3 ubiquitin-protein ligase TRIM69

2

5

High-throughput

0.606

High

874306

ZN655
Zinc finger protein 655

2

1

High-throughput

0.606

High

874321

SPAG5
Sperm-associated antigen 5

2

4

High-throughput

0.606

High

874330

PRD14
PR domain zinc finger protein 14

2

2

High-throughput

0.606

High

874333

CARD9
Caspase recruitment domain-containing protein 9

2

3

High-throughput

0.606

High

874336

ZN552
Zinc finger protein 552

2

1

High-throughput

0.606

High

874339

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

2

High-throughput

0.606

High

874344

PIHD1
PIH1 domain-containing protein 1

2

1

High-throughput

0.606

High

874345

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

874357

PLAL2
Zinc finger protein PLAGL2

2

1

High-throughput

0.606

High

874353

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

19

High-throughput

0.593

High

874266

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

2

1

Small-scale

0.584

High

330068

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

874279

MESD
LRP chaperone MESD

2

0

High-throughput

0.580

High

874294

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

874295

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.580

High

874310

DBF4B
Protein DBF4 homolog B

2

0

High-throughput

0.580

High

874313

MIPO1
Mirror-image polydactyly gene 1 protein

2

0

High-throughput

0.580

High

874316

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

874318

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

874323

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

2

0

High-throughput

0.580

High

874328

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.580

High

874331

KTBL1
KATNB1-like protein 1

2

0

High-throughput

0.580

High

874340

ZC4H2
Zinc finger C4H2 domain-containing protein

2

0

High-throughput

0.580

High

874354

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.580

High

874261

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.575

High

874329

TRI54
Tripartite motif-containing protein 54

1

18

High-throughput

0.573

High

874358

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.573

High

61851

CC88B
Coiled-coil domain-containing protein 88B

2

6

High-throughput

0.553

High

62282

GG6L9
Golgin subfamily A member 6-like protein 9

2

19

High-throughput

0.553

High

67022

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

237881

AP180
Clathrin coat assembly protein AP180

2

1

High-throughput

0.553

High

280552

KRT34
Keratin, type I cuticular Ha4

2

8

High-throughput

0.553

High

280784

KRT36
Keratin, type I cuticular Ha6

2

6

High-throughput

0.553

High

874256

KR108
Keratin-associated protein 10-8

2

3

High-throughput

0.553

High

874263

KRT83
Keratin, type II cuticular Hb3

2

3

High-throughput

0.553

High

874303

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

2

High-throughput

0.553

High

874305

USBP1
Harmonin-binding protein USHBP1

2

4

High-throughput

0.553

High

874317

HOOK2
Protein Hook homolog 2

2

7

High-throughput

0.553

High

874327

KIFC3
Kinesin-like protein KIFC3

2

3

High-throughput

0.553

High

874351

TRI10
Tripartite motif-containing protein 10

2

5

High-throughput

0.553

High

874359

COG6
Conserved oligomeric Golgi complex subunit 6

2

1

High-throughput

0.553

High

874356

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.553

High

551099

ITF2
Transcription factor 4

1

0

High-throughput

0.549

High

545788

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

627222

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.536

High

646749

1433T
14-3-3 protein theta

1

18

High-throughput

0.536

High

874258

1433G
14-3-3 protein gamma

1

18

High-throughput

0.536

High

874259

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.536

High

874260

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

874262

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.536

High

874335

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.536

High

874269

DEUP1
Deuterosome assembly protein 1

1

6

High-throughput

0.523

High

874288

C102B
Coiled-coil domain-containing protein 102B

1

1

High-throughput

0.523

High

874289

K1C40
Keratin, type I cytoskeletal 40

1

8

High-throughput

0.523

High

874298

NT2NA
Notch homolog 2 N-terminal-like protein A

1

2

High-throughput

0.523

High

874308

PNMA1
Paraneoplastic antigen Ma1

1

2

High-throughput

0.523

High

874319

COG8
Conserved oligomeric Golgi complex subunit 8

1

1

High-throughput

0.523

High

874252

CLD15
Claudin-15

1

0

High-throughput

0.518

High

614284

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

373005

VTNC
Vitronectin

1

1

High-throughput

0.508

High

429859

CATL1
Procathepsin L

1

1

High-throughput

0.508

High

874349

RBX2
RING-box protein 2

1

9

High-throughput

0.508

High

177245

HDAC3
Histone deacetylase 3

1

7

Small-scale

0.500

High

451224

TPM1
Tropomyosin alpha-1 chain

1

6

High-throughput

0.489

High

865135

SMTN
Smoothelin

1

4

High-throughput

0.489

High

362630

APOH
Beta-2-glycoprotein 1

1

0

High-throughput

0.486

High

602083

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.486

High

874253

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.486

High

874325

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

High-throughput

0.486

High

874296

CLC4G
C-type lectin domain family 4 member G

1

8

High-throughput

0.481

High

874322

MGLL
Monoglyceride lipase

1

1

High-throughput

0.481

High

874278

SCRB2
Lysosome membrane protein 2

1

2

High-throughput

0.479

High

874360

NCOR2
Nuclear receptor corepressor 2

1

1

Small-scale

0.479

High

2694

A0A0C4DFN3
Monoglyceride lipase

1

1

High-throughput

0.470

High

344462

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.464

High

528086

BMP1
Bone morphogenetic protein 1

1

4

High-throughput

0.464

High

874264

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

874267

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.457

High

874361

NEMO
NF-kappa-B essential modulator

1

17

High-throughput

0.457

High

874254

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.439

High

874257

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.439

High

874292

KLC3
Kinesin light chain 3

1

4

High-throughput

0.439

High

320669

LDOC1
Protein LDOC1

1

0

High-throughput

0.438

High

430456

APT
Adenine phosphoribosyltransferase

1

1

High-throughput

0.437

High

434363

TPM2
Tropomyosin beta chain

1

5

High-throughput

0.437

High

110650

H3BQF1
adenine phosphoribosyltransferase

1

1

High-throughput

0.407

High

874287

Q5TCU3
Tropomyosin beta chain

1

6

High-throughput

0.407

High

874348

TFP11
Tuftelin-interacting protein 11

4

0

High-throughput

0.364

High

216477

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

0

High-throughput

0.352

High

874307

IN80E
INO80 complex subunit E

3

0

High-throughput

0.352

High

252974

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

568444

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

874265

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.316

High

874275

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

874283

MSS51
Putative protein MSS51 homolog, mitochondrial

2

0

High-throughput

0.316

High

874299

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

2

0

High-throughput

0.316

High

874301

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.316

High

874302

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.316

High

874309

CA131
Uncharacterized protein C1orf131

2

0

High-throughput

0.316

High

874311

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

874312

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.316

High

874314

POF1B
Protein POF1B

2

0

High-throughput

0.316

High

874320

TGM7
Protein-glutamine gamma-glutamyltransferase Z

2

0

High-throughput

0.316

High

874326

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.316

High

874342

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.316

High

874343

SPAT6
Spermatogenesis-associated protein 6

2

0

High-throughput

0.316

High

874347

LR2BP
LRP2-binding protein

2

0

High-throughput

0.316

High

874350

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.316

High

847180

GALK1
Galactokinase

1

0

High-throughput

0.279

Low

874332

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

121284

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024