Protein: LHX2
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)

Gene: LHX2
Organism: Homo sapiens
Interactions: 177
UniProt ID: P50458

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

839771

LDB1
LIM domain-binding protein 1

4

20

High-throughput

0.904

High

678891

HXC8
Homeobox protein Hox-C8

2

14

High-throughput

0.783

High

839736

PO4F2
POU domain, class 4, transcription factor 2

2

15

High-throughput

0.783

High

839831

HOME3
Homer protein homolog 3

2

3

High-throughput

0.700

High

839819

SSBP3
Single-stranded DNA-binding protein 3

3

20

High-throughput

0.667

High

641346

PAX6
Paired box protein Pax-6

1

9

Small-scale

0.647

High

658623

MSX1
Homeobox protein MSX-1

1

19

Small-scale

0.647

High

764609

CUX1
Homeobox protein cut-like 1

1

17

High-throughput

0.618

High

839731

SATB1
DNA-binding protein SATB1

1

7

High-throughput

0.618

High

839743

MEF2D
Myocyte-specific enhancer factor 2D

1

3

High-throughput

0.618

High

839748

ZFHX3
Zinc finger homeobox protein 3

1

11

High-throughput

0.618

High

839758

BCORL
BCL-6 corepressor-like protein 1

1

6

High-throughput

0.618

High

839767

BCOR
BCL-6 corepressor

1

14

High-throughput

0.618

High

839773

ZFHX4
Zinc finger homeobox protein 4

1

13

High-throughput

0.618

High

839777

MGAP
MAX gene-associated protein

1

7

High-throughput

0.618

High

839800

ISL2
Insulin gene enhancer protein ISL-2

1

18

High-throughput

0.618

High

839806

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

16

High-throughput

0.618

High

839827

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

14

High-throughput

0.618

High

839839

TRPS1
Zinc finger transcription factor Trps1

1

18

High-throughput

0.618

High

839846

SATB2
DNA-binding protein SATB2

1

7

High-throughput

0.618

High

839856

ZHX2
Zinc fingers and homeoboxes protein 2

1

19

High-throughput

0.618

High

839818

SSBP4
Single-stranded DNA-binding protein 4

2

20

High-throughput

0.611

High

474047

UBFL1
Upstream-binding factor 1-like protein 1

2

16

High-throughput

0.606

High

839750

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

5

High-throughput

0.606

High

839781

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

2

High-throughput

0.606

High

839783

ZN511
Zinc finger protein 511

2

2

High-throughput

0.606

High

839789

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.606

High

839809

ZFP42
Zinc finger protein 42 homolog

2

15

High-throughput

0.606

High

839843

TLK1
Serine/threonine-protein kinase tousled-like 1

2

3

High-throughput

0.606

High

839844

TPC2L
Trafficking protein particle complex subunit 2-like protein

2

1

High-throughput

0.606

High

839852

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

2

1

High-throughput

0.606

High

839756

FWCH1
FLYWCH-type zinc finger-containing protein 1

2

0

High-throughput

0.580

High

839766

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.580

High

839838

MO4L1
Mortality factor 4-like protein 1

2

0

High-throughput

0.580

High

135095

NFIB
Nuclear factor 1 B-type

1

10

High-throughput

0.578

High

839737

NFIA
Nuclear factor 1 A-type

1

14

High-throughput

0.578

High

839814

CITE2
Cbp/p300-interacting transactivator 2

1

1

Small-scale

0.573

High

443154

NFIC
Nuclear factor 1 C-type

1

14

High-throughput

0.561

High

839792

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

7

High-throughput

0.555

High

64673

RHG32
Rho GTPase-activating protein 32

2

3

High-throughput

0.553

High

837147

KHK
Ketohexokinase

2

1

High-throughput

0.553

High

839811

OSMR
Oncostatin-M-specific receptor subunit beta

2

5

High-throughput

0.553

High

839854

PYGO1
Pygopus homolog 1

1

20

High-throughput

0.536

High

839841

DNM3L
DNA

1

0

Small-scale

0.480

High

839733

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.479

High

146182

ARI1A
AT-rich interactive domain-containing protein 1A

1

19

High-throughput

0.479

High

152615

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164203

ZN609
Zinc finger protein 609

1

9

High-throughput

0.479

High

167146

ZN536
Zinc finger protein 536

1

6

High-throughput

0.479

High

170302

TIF1A
Transcription intermediary factor 1-alpha

1

10

High-throughput

0.479

High

175759

HMGB3
High mobility group protein B3

1

13

High-throughput

0.479

High

183085

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

224361

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

231216

ZEB2
Zinc finger E-box-binding homeobox 2

1

7

High-throughput

0.479

High

256392

PHF2
Lysine-specific demethylase PHF2

1

5

High-throughput

0.479

High

261442

NCOR1
Nuclear receptor corepressor 1

1

18

High-throughput

0.479

High

265619

E2F6
Transcription factor E2F6

1

3

High-throughput

0.479

High

321734

WIZ
Protein Wiz

1

9

High-throughput

0.479

High

449608

HMGB1
High mobility group protein B1

1

20

High-throughput

0.479

High

508400

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.479

High

525296

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

16

High-throughput

0.479

High

550345

ZEP1
Zinc finger protein 40

1

18

High-throughput

0.479

High

632652

TYY1
Transcriptional repressor protein YY1

1

14

High-throughput

0.479

High

658642

SMCA1
Probable global transcription activator SNF2L1

1

11

High-throughput

0.479

High

722197

RFC1
Replication factor C subunit 1

1

5

High-throughput

0.479

High

823708

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

19

High-throughput

0.479

High

830844

CTCF
Transcriptional repressor CTCF

1

4

High-throughput

0.479

High

839720

SMCA2
Probable global transcription activator SNF2L2

1

11

High-throughput

0.479

High

839721

SMCA4
Transcription activator BRG1

1

12

High-throughput

0.479

High

839722

BLM
RecQ-like DNA helicase BLM

1

2

High-throughput

0.479

High

839723

ATX1
Ataxin-1

1

5

High-throughput

0.479

High

839725

SSBP2
Single-stranded DNA-binding protein 2

1

20

High-throughput

0.479

High

839729

FOXK1
Forkhead box protein K1

1

11

High-throughput

0.479

High

839730

TFAM
Transcription factor A, mitochondrial

1

15

High-throughput

0.479

High

839732

TLE1
Transducin-like enhancer protein 1

1

12

High-throughput

0.479

High

839734

RING1
E3 ubiquitin-protein ligase RING1

1

5

High-throughput

0.479

High

839735

TLE5
TLE family member 5

1

10

High-throughput

0.479

High

839738

PWP1
Periodic tryptophan protein 1 homolog

1

3

High-throughput

0.479

High

839740

SMC1A
Structural maintenance of chromosomes protein 1A

1

5

High-throughput

0.479

High

839741

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.479

High

839742

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.479

High

839744

RBBP5
Retinoblastoma-binding protein 5

1

1

High-throughput

0.479

High

839745

SSXT
Protein SSXT

1

13

High-throughput

0.479

High

839746

ELF2
ETS-related transcription factor Elf-2

1

6

High-throughput

0.479

High

839747

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

High-throughput

0.479

High

839749

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

839754

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

839755

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

8

High-throughput

0.479

High

839762

TSH3
Teashirt homolog 3

1

11

High-throughput

0.479

High

839763

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

839768

PAXI1
PAX-interacting protein 1

1

12

High-throughput

0.479

High

839769

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.479

High

839770

POGZ
Pogo transposable element with ZNF domain

1

8

High-throughput

0.479

High

839772

PB1
Protein polybromo-1

1

16

High-throughput

0.479

High

839774

BCL9L
B-cell CLL/lymphoma 9-like protein

1

20

High-throughput

0.479

High

839775

FOXP4
Forkhead box protein P4

1

15

High-throughput

0.479

High

839776

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

839778

HOMEZ
Homeobox and leucine zipper protein Homez

1

19

High-throughput

0.479

High

839780

ZN687
Zinc finger protein 687

1

5

High-throughput

0.479

High

839785

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

839786

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

839787

KDM2B
Lysine-specific demethylase 2B

1

5

High-throughput

0.479

High

839788

SMRC2
SWI/SNF complex subunit SMARCC2

1

18

High-throughput

0.479

High

839791

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

839793

RREB1
Ras-responsive element-binding protein 1

1

4

High-throughput

0.479

High

839794

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

839795

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

839796

SMRC1
SWI/SNF complex subunit SMARCC1

1

18

High-throughput

0.479

High

839797

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

18

High-throughput

0.479

High

839798

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

High-throughput

0.479

High

839799

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

5

High-throughput

0.479

High

839802

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

12

High-throughput

0.479

High

839804

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

7

High-throughput

0.479

High

839805

Z512B
Zinc finger protein 512B

1

12

High-throughput

0.479

High

839807

EP400
E1A-binding protein p400

1

13

High-throughput

0.479

High

839808

ZN512
Zinc finger protein 512

1

9

High-throughput

0.479

High

839810

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

839813

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

839816

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

8

High-throughput

0.479

High

839820

GTPB4
GTP-binding protein 4

1

3

High-throughput

0.479

High

839821

REXO4
RNA exonuclease 4

1

1

High-throughput

0.479

High

839823

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

1

High-throughput

0.479

High

839824

FOXP1
Forkhead box protein P1

1

15

High-throughput

0.479

High

839825

ZN644
Zinc finger protein 644

1

8

High-throughput

0.479

High

839826

DDX31
ATP-dependent DNA helicase DDX31

1

1

High-throughput

0.479

High

839829

BRD7
Bromodomain-containing protein 7

1

8

High-throughput

0.479

High

839830

HELLS
Lymphoid-specific helicase

1

12

High-throughput

0.479

High

839834

DDX56
Probable ATP-dependent RNA helicase DDX56

1

5

High-throughput

0.479

High

839836

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

6

High-throughput

0.479

High

839837

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

High-throughput

0.479

High

839840

BAZ1B
Tyrosine-protein kinase BAZ1B

1

17

High-throughput

0.479

High

839847

SMC3
Structural maintenance of chromosomes protein 3

1

4

High-throughput

0.479

High

839855

NCOR2
Nuclear receptor corepressor 2

1

19

High-throughput

0.479

High

839753

Q49AR9
ANKS1A protein

1

2

High-throughput

0.470

High

773278

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.458

High

839724

PSME3
Proteasome activator complex subunit 3

1

0

Small-scale

0.458

High

839739

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.458

High

839752

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.458

High

839760

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

839765

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.458

High

839790

NOC3L
Nucleolar complex protein 3 homolog

1

0

High-throughput

0.458

High

839828

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

787709

HUTH
Histidine ammonia-lyase

1

2

High-throughput

0.457

High

131704

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.437

High

322347

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.437

High

789390

RBM34
RNA-binding protein 34

1

2

High-throughput

0.437

High

839727

RT15
Small ribosomal subunit protein uS15m

1

1

High-throughput

0.437

High

839757

IF44L
Interferon-induced protein 44-like

1

1

High-throughput

0.437

High

839761

ZMYM4
Zinc finger MYM-type protein 4

1

11

High-throughput

0.437

High

839779

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

2

High-throughput

0.437

High

839803

DDX27
Probable ATP-dependent RNA helicase DDX27

1

2

High-throughput

0.437

High

839817

CG050
Uncharacterized protein C7orf50

1

3

High-throughput

0.437

High

839822

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

839833

RBM28
RNA-binding protein 28

1

4

High-throughput

0.437

High

839845

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

839849

DDX52
Probable ATP-dependent RNA helicase DDX52

1

1

High-throughput

0.437

High

839850

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.437

High

839851

NOP16
Nucleolar protein 16

1

1

High-throughput

0.437

High

839751

LEGL
Galectin-related protein

2

0

High-throughput

0.316

High

839784

BEND2
BEN domain-containing protein 2

2

0

High-throughput

0.316

High

839832

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

62905

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.249

Low

273038

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.249

Low

802018

NOP2
Probable 28S rRNA

1

0

High-throughput

0.249

Low

839719

RT29
Small ribosomal subunit protein mS29

1

0

High-throughput

0.249

Low

839726

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.249

Low

839728

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.249

Low

839759

RRP12
RRP12-like protein

1

0

High-throughput

0.249

Low

839764

RL7L
Ribosomal protein uL30-like

1

0

High-throughput

0.249

Low

839782

KRI1
Protein KRI1 homolog

1

0

High-throughput

0.249

Low

839801

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.249

Low

839812

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.249

Low

839815

DDX50
ATP-dependent RNA helicase DDX50

1

0

High-throughput

0.249

Low

839835

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.249

Low

839842

MRT4
mRNA turnover protein 4 homolog

1

0

High-throughput

0.249

Low

839848

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.249

Low

839853

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024