Protein: PFD2
Prefoldin subunit 2

Gene: PFD2, PFDN2
Organism: Homo sapiens
Interactions: 219
UniProt ID: Q9UHV9

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

901756

PFD3
Prefoldin subunit 3

10

4

Small-scale

0.973

High

295690

RMP
Unconventional prefoldin RPB5 interactor 1

9

4

Small-scale

0.967

High

1304034

PFD5
Prefoldin subunit 5

7

3

Small-scale

0.962

High

1354072

UXT
Protein UXT

6

1

Small-scale

0.943

High

246057

PFD1
Prefoldin subunit 1

5

1

Small-scale

0.920

High

171695

PFD6
Prefoldin subunit 6

3

2

High-throughput

0.861

High

1343511

PFD4
Prefoldin subunit 4

3

2

High-throughput

0.861

High

1345931

PDRG1
p53 and DNA damage-regulated protein 1

4

0

High-throughput

0.849

High

1332515

RPAP3
RNA polymerase II-associated protein 3

7

0

Small-scale

0.713

High

738108

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

2

High-throughput

0.694

High

614160

TBG1
Tubulin gamma-1 chain

4

4

High-throughput

0.683

High

906189

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

2

Small-scale

0.671

High

1313656

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

3

3

High-throughput

0.667

High

1326489

SKI8
Superkiller complex protein 8

3

4

High-throughput

0.667

High

1347026

RPC2
DNA-directed RNA polymerase III subunit RPC2

3

2

High-throughput

0.667

High

1355598

RUVB2
RuvB-like 2

3

2

High-throughput

0.667

High

1175232

TBA1A
Tubulin alpha-1A chain

4

6

High-throughput

0.666

High

1026888

MK07
Mitogen-activated protein kinase 7

4

0

High-throughput

0.661

High

156079

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

3

High-throughput

0.656

High

903048

DCAF7
DDB1- and CUL4-associated factor 7

3

4

High-throughput

0.656

High

583836

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

0

High-throughput

0.646

High

1038788

HDAC1
Histone deacetylase 1

2

2

High-throughput

0.628

High

1134086

DCA12
DDB1- and CUL4-associated factor 12

2

1

High-throughput

0.628

High

1265913

DDB2
DNA damage-binding protein 2

2

6

High-throughput

0.628

High

1349193

DTL
Denticleless protein homolog

2

4

High-throughput

0.628

High

1298316

DAA10
Dynein axonemal assembly factor 10

3

0

High-throughput

0.628

High

1347308

PIHD1
PIH1 domain-containing protein 1

3

0

Small-scale

0.628

High

1350559

WRP73
WD repeat-containing protein WRAP73

2

4

High-throughput

0.621

High

771088

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.618

High

826934

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.618

High

843087

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.618

High

843427

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.618

High

1151022

Q6FH24
Prefoldin subunit 3

1

4

High-throughput

0.618

High

1306731

TCPH
T-complex protein 1 subunit eta

1

2

High-throughput

0.618

High

169984

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.611

High

318747

EYA4
Eyes absent homolog 4

2

3

High-throughput

0.611

High

921768

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

2

6

High-throughput

0.611

High

1246052

NEDD1
Protein NEDD1

2

4

High-throughput

0.611

High

1253306

POC1B
POC1 centriolar protein homolog B

2

5

High-throughput

0.611

High

1348663

WSB2
WD repeat and SOCS box-containing protein 2

2

4

High-throughput

0.611

High

960455

CDK17
Cyclin-dependent kinase 17

2

0

High-throughput

0.602

High

1191091

WAPL
Wings apart-like protein homolog

2

0

High-throughput

0.602

High

1221389

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.602

High

1306329

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

0

High-throughput

0.602

High

1355601

KLDC2
Kelch domain-containing protein 2

2

0

High-throughput

0.602

High

1288366

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

3

High-throughput

0.601

High

1355594

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.586

High

854393

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

0

High-throughput

0.585

High

1346863

RPC5
DNA-directed RNA polymerase III subunit RPC5

2

0

High-throughput

0.585

High

1028036

ERCC8
DNA excision repair protein ERCC-8

2

4

Small-scale

0.584

High

1033351

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

3

High-throughput

0.584

High

1244548

NUP43
Nucleoporin Nup43

2

4

High-throughput

0.584

High

64165

ZN726
Zinc finger protein 726

2

0

High-throughput

0.580

High

421415

ACBP
Acyl-CoA-binding protein

2

0

High-throughput

0.580

High

236260

PRP17
Pre-mRNA-processing factor 17

2

4

High-throughput

0.574

High

348167

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.571

High

772198

VHL
von Hippel-Lindau disease tumor suppressor

2

0

Small-scale

0.559

High

317181

RPA1
DNA-directed RNA polymerase I subunit RPA1

2

3

High-throughput

0.558

High

1335223

RC3H2
Roquin-2

2

1

High-throughput

0.558

High

134796

PEX7
Peroxisomal targeting signal 2 receptor

1

3

High-throughput

0.536

High

265441

KTNA1
Katanin p60 ATPase-containing subunit A1

1

1

High-throughput

0.536

High

677048

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.536

High

885064

FBXW4
F-box/WD repeat-containing protein 4

1

5

High-throughput

0.536

High

915299

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

2

High-throughput

0.536

High

933385

TBA1B
Tubulin alpha-1B chain

1

6

High-throughput

0.536

High

934016

TBB4B
Tubulin beta-4B chain

1

2

High-throughput

0.536

High

1024606

CAF1B
Chromatin assembly factor 1 subunit B

1

3

High-throughput

0.536

High

1268702

FAN
Protein FAN

1

2

High-throughput

0.536

High

1295356

DCAF5
DDB1- and CUL4-associated factor 5

1

5

High-throughput

0.536

High

1304609

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

1

High-throughput

0.536

High

1313381

TRAF4
TNF receptor-associated factor 4

1

1

High-throughput

0.536

High

1336405

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.536

High

1355151

LIMD1
LIM domain-containing protein 1

1

1

High-throughput

0.536

High

1355599

RUVB1
RuvB-like 1

1

2

High-throughput

0.536

High

1137971

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

2

2

High-throughput

0.533

High

878152

PKNX1
Homeobox protein PKNOX1

1

0

High-throughput

0.518

High

883399

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

0

High-throughput

0.518

High

1119506

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.515

High

1161218

TBA3E
Tubulin alpha-3E chain

1

5

High-throughput

0.515

High

64750

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.513

High

128663

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

165097

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.513

High

259982

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

0

High-throughput

0.513

High

336614

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

389603

TYSY
Thymidylate synthase

1

0

High-throughput

0.513

High

621286

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.513

High

865012

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

878111

ANM2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.513

High

1066013

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1069555

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1108549

PCGF3
Polycomb group RING finger protein 3

1

0

High-throughput

0.513

High

1110285

KR133
Keratin-associated protein 13-3

1

0

High-throughput

0.513

High

1125694

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

1160853

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

0

High-throughput

0.513

High

1174869

LARP4
La-related protein 4

1

0

High-throughput

0.513

High

1190622

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.513

High

1243438

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1264766

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.513

High

1282174

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.513

High

1327089

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.513

High

1347569

UCKL1
Uridine-cytidine kinase-like 1

1

0

High-throughput

0.513

High

1355091

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.513

High

1306394

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.493

High

682404

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.493

High

925710

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.493

High

1138937

DC122
DDB1- and CUL4-associated factor 12-like protein 2

1

1

High-throughput

0.489

High

1163047

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

3

High-throughput

0.489

High

1313449

WDR18
WD repeat-containing protein 18

1

5

High-throughput

0.489

High

1355595

GPN3
GPN-loop GTPase 3

1

1

High-throughput

0.489

High

148117

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.479

High

154699

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

7

High-throughput

0.479

High

257232

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

1

High-throughput

0.479

High

379993

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

428486

TBB5
Tubulin beta chain

1

2

High-throughput

0.479

High

554000

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

570156

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

583621

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

625087

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

High-throughput

0.479

High

738909

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

3

High-throughput

0.479

High

854493

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

1

High-throughput

0.479

High

897147

ACTZ
Alpha-centractin

1

1

High-throughput

0.479

High

913978

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

921189

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.479

High

933657

TBA4A
Tubulin alpha-4A chain

1

6

High-throughput

0.479

High

967499

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

1026576

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1074506

SKI2
Superkiller complex protein 2

1

2

High-throughput

0.479

High

1116782

DUS28
Dual specificity phosphatase 28

1

1

High-throughput

0.479

High

1123684

DCAF6
DDB1- and CUL4-associated factor 6

1

6

High-throughput

0.479

High

1123957

Q59G26
Guanine nucleotide-binding protein, beta-3 subunit variant

1

6

High-throughput

0.479

High

1161422

SKI3
Superkiller complex protein 3

1

1

High-throughput

0.479

High

1234398

WDTC1
WD and tetratricopeptide repeats protein 1

1

5

High-throughput

0.479

High

1240476

POC1A
POC1 centriolar protein homolog A

1

5

High-throughput

0.479

High

1270508

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.479

High

1299014

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.479

High

1334524

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.479

High

1343465

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

2

High-throughput

0.479

High

1355596

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

1355597

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

1

High-throughput

0.479

High

1355600

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

1355602

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

3

High-throughput

0.479

High

1355604

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

1

High-throughput

0.479

High

125779

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

179874

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

181480

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

270235

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

295364

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

298865

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

323267

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

375056

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

402762

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

534151

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.458

High

617699

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

652541

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

673111

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

780275

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

807871

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

813821

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

832764

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

870924

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

881056

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

896252

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

896842

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

896992

ARP2
Actin-related protein 2

1

0

High-throughput

0.458

High

897657

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

897851

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

909289

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

913166

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1016260

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1050291

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1064813

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1076301

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1159326

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1172160

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1174322

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1184371

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1204360

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1239614

AFG2A
ATPase family gene 2 protein homolog A

1

0

High-throughput

0.458

High

1240826

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

1245221

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1259804

SMAP2
Stromal membrane-associated protein 2

1

0

High-throughput

0.458

High

1267226

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1272677

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1284838

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.458

High

1285588

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

1294112

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1307351

DUS9
Dual specificity protein phosphatase 9

1

0

High-throughput

0.458

High

1326200

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

1331562

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1332733

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1354757

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1355603

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

92589

E9PLN6
Eyes absent homolog

1

2

High-throughput

0.445

High

1151057

Q6FHM2
Epididymis secretory sperm binding protein

1

6

High-throughput

0.437

High

1176279

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.437

High

1319312

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

1349932

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

3

High-throughput

0.437

High

207667

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.426

High

497751

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

529868

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

831770

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

742587

SYUA
Alpha-synuclein

1

0

Small-scale

0.391

High

1182974

SPT6H
Transcription elongation factor SPT6

2

0

High-throughput

0.328

High

1260949

DCAF4
DDB1- and CUL4-associated factor 4

2

0

High-throughput

0.328

High

1173339

NEK10
Serine/threonine-protein kinase Nek10

2

0

High-throughput

0.313

High

602019

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

0

High-throughput

0.300

High

1235851

DB123
Beta-defensin 123

1

0

High-throughput

0.279

Low

206132

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

239627

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

721717

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1012555

K2012
Uncharacterized protein KIAA2012

1

0

High-throughput

0.249

Low

1087849

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.249

Low

1150719

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

1252234

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1273180

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

1326452

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1355572

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.249

Low

581883

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024