HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: NEST (P48681)
Nestin
Gene: NES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1621
+	Mm
		432405 HS90A_MOUSE (1-732): 0: 1083: 97.82		K2C8_MOUSE (7-315): 7.66e-124: 399: 23.99
+	Hs
		431447 HS90A_HUMAN (1-732): 0: 1087: 100.00		VIME_HUMAN (8-343): 3.05e-118: 382: 28.32
+	Hs
		432221 HS90A_HUMAN (1-732): 0: 1087: 100.00		CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11
+	Hs
		438486 HS90B_HUMAN (19-732): 0: 1059: 86.13		CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11
+	Hs
		431590 HS90A_HUMAN (1-732): 0: 1087: 100.00		MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48
+	Hs
		431857 HS90A_HUMAN (1-732): 0: 1087: 100.00		NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02
+	Hs
		431480 HS90A_HUMAN (1-732): 0: 1087: 100.00		MYH7_HUMAN (1-522): 5.76e-18: 93.1: 9.19
+	Hs
		431893 HS90A_HUMAN (1-732): 0: 1087: 100.00		AINX_HUMAN (8-317): 2.29e-17: 89.4: 27.59
+	Hs
		437945 HS90B_HUMAN (19-732): 0: 1059: 86.13		MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48
+	Hs
		438176 HS90B_HUMAN (19-732): 0: 1059: 86.13		NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02