Protein: PFD4
Prefoldin subunit 4 (Protein C-1)

Gene: PFD4, PFDN4
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q9NQP4

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

901746

PFD3
Prefoldin subunit 3

6

2

High-throughput

0.954

High

171681

PFD6
Prefoldin subunit 6

5

2

High-throughput

0.927

High

246047

PFD1
Prefoldin subunit 1

3

1

High-throughput

0.861

High

1304019

PFD5
Prefoldin subunit 5

3

2

High-throughput

0.861

High

1343511

PFD2
Prefoldin subunit 2

3

2

High-throughput

0.861

High

1343506

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.770

High

295680

RMP
Unconventional prefoldin RPB5 interactor 1

1

3

High-throughput

0.691

High

1026883

MK07
Mitogen-activated protein kinase 7

4

1

High-throughput

0.691

High

903032

DCAF7
DDB1- and CUL4-associated factor 7

3

3

High-throughput

0.667

High

921739

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

3

4

High-throughput

0.667

High

1028029

ERCC8
DNA excision repair protein ERCC-8

3

4

Small-scale

0.667

High

1265901

DDB2
DNA damage-binding protein 2

3

6

High-throughput

0.667

High

1295350

DCAF5
DDB1- and CUL4-associated factor 5

3

5

High-throughput

0.667

High

1313652

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

3

4

High-throughput

0.667

High

1103451

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

2

1

High-throughput

0.628

High

1128415

SPIN3
Spindlin-3

2

1

High-throughput

0.628

High

1246041

NEDD1
Protein NEDD1

2

6

High-throughput

0.628

High

1308687

SPI2B
Spindlin-2B

2

1

High-throughput

0.628

High

1326482

SKI8
Superkiller complex protein 8

2

5

High-throughput

0.628

High

826903

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.618

High

843067

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.618

High

843404

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.618

High

1306697

TCPH
T-complex protein 1 subunit eta

1

2

High-throughput

0.618

High

265434

KTNA1
Katanin p60 ATPase-containing subunit A1

2

0

High-throughput

0.602

High

475201

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.602

High

1327079

MFR1L
Mitochondrial fission regulator 1-like

2

0

High-throughput

0.602

High

1343508

MIOS
GATOR2 complex protein MIOS

2

0

High-throughput

0.602

High

1343509

UXT
Protein UXT

1

0

Small-scale

0.586

High

1307346

DUS9
Dual specificity protein phosphatase 9

2

1

High-throughput

0.584

High

1343512

FBW1B
F-box/WD repeat-containing protein 11

2

7

High-throughput

0.584

High

272949

RFPL3
Ret finger protein-like 3

2

0

High-throughput

0.580

High

1163040

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

6

High-throughput

0.574

High

1224090

RUSD2
Pseudouridylate synthase RPUSD2

2

1

High-throughput

0.574

High

1038739

HDAC1
Histone deacetylase 1

2

0

High-throughput

0.547

High

547855

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

933364

TBA1B
Tubulin alpha-1B chain

1

3

High-throughput

0.536

High

1024599

CAF1B
Chromatin assembly factor 1 subunit B

1

4

High-throughput

0.536

High

1251672

UHMK1
Serine/threonine-protein kinase Kist

1

1

High-throughput

0.536

High

1343510

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

1

High-throughput

0.536

High

197091

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

4

High-throughput

0.515

High

1161217

TBA3E
Tubulin alpha-3E chain

1

2

High-throughput

0.515

High

64745

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.513

High

556984

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

933990

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

1087938

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

0

High-throughput

0.513

High

1108547

PCGF3
Polycomb group RING finger protein 3

1

0

High-throughput

0.513

High

1110279

KR133
Keratin-associated protein 13-3

1

0

High-throughput

0.513

High

1198070

KAISO
Transcriptional regulator Kaiso

1

0

High-throughput

0.513

High

1271764

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1304604

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

0

High-throughput

0.513

High

147562

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.493

High

1343515

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.493

High

1198556

WDR86
WD repeat-containing protein 86

1

8

High-throughput

0.489

High

148112

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

4

High-throughput

0.479

High

570093

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

903538

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

1033342

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

4

High-throughput

0.479

High

1074500

SKI2
Superkiller complex protein 2

1

2

High-throughput

0.479

High

1123675

DCAF6
DDB1- and CUL4-associated factor 6

1

6

High-throughput

0.479

High

1175204

TBA1A
Tubulin alpha-1A chain

1

3

High-throughput

0.479

High

1234387

WDTC1
WD and tetratricopeptide repeats protein 1

1

5

High-throughput

0.479

High

1240467

POC1A
POC1 centriolar protein homolog A

1

5

High-throughput

0.479

High

1253302

POC1B
POC1 centriolar protein homolog B

1

5

High-throughput

0.479

High

1259413

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.479

High

1284818

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.479

High

1343513

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

1343517

FBW1A
F-box/WD repeat-containing protein 1A

1

7

High-throughput

0.479

High

271796

PRDM1
PR domain zinc finger protein 1

1

0

High-throughput

0.458

High

347977

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

485145

GLI3
Transcriptional activator GLI3

1

0

High-throughput

0.458

High

772173

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

785416

ELK3
ETS domain-containing protein Elk-3

1

0

High-throughput

0.458

High

932393

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1021260

FOXI1
Forkhead box protein I1

1

0

High-throughput

0.458

High

1030499

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1074420

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1134082

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1158328

CDC73
Parafibromin

1

0

High-throughput

0.458

High

1161416

SKI3
Superkiller complex protein 3

1

0

High-throughput

0.458

High

1171848

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1186269

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.458

High

1285708

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1298762

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.458

High

1304992

KLF6
Krueppel-like factor 6

1

0

High-throughput

0.458

High

1306383

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.458

High

1335842

CENPJ
Centromere protein J

1

0

High-throughput

0.458

High

1343516

B9D1
B9 domain-containing protein 1

1

0

High-throughput

0.458

High

1343518

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.458

High

1161728

TTC33
Tetratricopeptide repeat protein 33

1

1

High-throughput

0.437

High

320024

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.426

High

790887

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

High-throughput

0.426

High

1335186

RC3H2
Roquin-2

3

0

High-throughput

0.347

High

1223194

ZZZ3
ZZ-type zinc finger-containing protein 3

2

0

High-throughput

0.328

High

1343507

FBX28
F-box only protein 28

2

0

High-throughput

0.328

High

602009

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

0

High-throughput

0.300

High

1173334

NEK10
Serine/threonine-protein kinase Nek10

1

0

High-throughput

0.279

Low

1182959

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.279

Low

1235848

DB123
Beta-defensin 123

1

0

High-throughput

0.279

Low

1238530

BANP
Protein BANP

1

0

High-throughput

0.279

Low

239618

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

1343514

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024