Protein: TF3C2
General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta)

Gene: TF3C2, GTF3C2
Organism: Homo sapiens
Interactions: 162
UniProt ID: Q8WUA4

Gene Ontology (top 5):
GO:0000127 - transcription factor TFIIIC complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0005654 - nucleoplasm
GO:0006383 - transcription by RNA polymerase III
GO:0042791 - 5S class rRNA transcription by RNA polymerase III

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1259893

FBXW7
F-box/WD repeat-containing protein 7

2

0

Small-scale

0.716

High

603615

FBRL
rRNA 2'-O-methyltransferase fibrillarin

5

0

High-throughput

0.682

High

1016393

TF3C1
General transcription factor 3C polypeptide 1

5

0

Small-scale

0.676

High

1259933

TF3C3
General transcription factor 3C polypeptide 3

4

0

Small-scale

0.664

High

1230000

RPTOR
Regulatory-associated protein of mTOR

1

1

Small-scale

0.646

High

1259926

TF3C4
General transcription factor 3C polypeptide 4

3

0

Small-scale

0.645

High

935024

H31
Histone H3.1

3

2

High-throughput

0.640

High

212951

STX6
Syntaxin-6

3

0

High-throughput

0.638

High

550876

RS2
Small ribosomal subunit protein uS5

3

0

High-throughput

0.638

High

1259923

RBM27
RNA-binding protein 27

1

1

High-throughput

0.618

High

1259932

TF3C5
General transcription factor 3C polypeptide 5

3

0

Small-scale

0.613

High

787533

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.613

High

347424

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.611

High

1259896

ZN764
Zinc finger protein 764

3

1

High-throughput

0.604

High

1060579

ZN638
Zinc finger protein 638

2

0

High-throughput

0.602

High

1259907

BAG1
BAG family molecular chaperone regulator 1

2

0

High-throughput

0.602

High

182842

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.586

High

1080154

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.586

High

1259905

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.586

High

1259922

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.586

High

1259930

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.586

High

66684

ZN785
Zinc finger protein 785

2

1

High-throughput

0.574

High

713125

SDC2
Syndecan-2

2

1

High-throughput

0.574

High

1259899

PNMA5
Paraneoplastic antigen-like protein 5

2

1

High-throughput

0.574

High

370082

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1259890

ESR2
Estrogen receptor beta

2

2

High-throughput

0.571

High

455689

PARP1
Poly [ADP-ribose] polymerase 1

2

0

High-throughput

0.559

High

553274

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

651778

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

721001

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

918546

H2B1C
Histone H2B type 1-C/E/F/G/I

2

0

High-throughput

0.559

High

1039716

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.546

High

414339

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.537

High

861863

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.536

High

953105

PR20A
Proline-rich protein 20A

2

1

High-throughput

0.533

High

149098

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.517

High

908873

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.517

High

1170973

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.517

High

160681

AURKA
Aurora kinase A

1

0

High-throughput

0.513

High

238277

RAD1
Cell cycle checkpoint protein RAD1

1

0

High-throughput

0.513

High

245722

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

782367

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

805740

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

1070569

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.513

High

1259895

TRM61
tRNA

1

0

High-throughput

0.513

High

1259915

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.513

High

952977

PR20E
Proline-rich protein 20E

2

1

High-throughput

0.504

High

208923

FOXS1
Forkhead box protein S1

1

1

High-throughput

0.489

High

243521

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.489

High

680375

SDC4
Syndecan-4

1

1

High-throughput

0.489

High

971836

HEN2
Helix-loop-helix protein 2

1

1

High-throughput

0.489

High

1135206

RBM26
RNA-binding protein 26

1

1

High-throughput

0.489

High

1259906

FOXB1
Forkhead box protein B1

1

2

High-throughput

0.489

High

1259912

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.489

High

1259927

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

974618

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.481

High

589897

TBP
TATA-box-binding protein

1

0

Small-scale

0.480

High

890768

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

902683

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

244692

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

379650

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

632828

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

636380

DNJB1
DnaJ homolog subfamily B member 1

1

1

High-throughput

0.479

High

708487

MCM4
DNA replication licensing factor MCM4

1

2

High-throughput

0.479

High

782599

HNF4A
Hepatocyte nuclear factor 4-alpha

1

2

High-throughput

0.479

High

808796

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

828316

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

832594

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

952492

H33
Histone H3.3

1

2

High-throughput

0.479

High

998911

EP300
Histone acetyltransferase p300

1

1

Small-scale

0.479

High

1078597

SMAD2
Mothers against decapentaplegic homolog 2

1

1

Small-scale

0.479

High

1078733

SMAD1
Mothers against decapentaplegic homolog 1

1

1

Small-scale

0.479

High

1259914

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

772079

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

122897

MEN1
Menin

1

0

High-throughput

0.458

High

262519

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

295051

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

319942

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

387182

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

442337

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

641494

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.458

High

917646

H4
Histone H4

1

0

High-throughput

0.458

High

961209

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

967927

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1035922

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1085850

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1236395

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1239137

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.458

High

1256295

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1259891

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

1259901

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1259909

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

Small-scale

0.458

High

1259913

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1259916

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

0

High-throughput

0.458

High

1259917

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1259921

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1259925

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

708992

MCM7
DNA replication licensing factor MCM7

1

2

Small-scale

0.445

High

229709

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.437

High

1067066

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.437

High

1259892

TF3C6
General transcription factor 3C polypeptide 6

1

0

Small-scale

0.426

High

1259903

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

990200

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

4

0

Small-scale

0.360

High

159727

CASQ2
Calsequestrin-2

3

0

High-throughput

0.347

High

270881

CLC3A
C-type lectin domain family 3 member A

2

0

High-throughput

0.328

High

555171

CD44
CD44 antigen

2

0

High-throughput

0.328

High

1237567

DDX51
ATP-dependent RNA helicase DDX51

2

0

High-throughput

0.328

High

1239086

ZN579
Zinc finger protein 579

2

0

High-throughput

0.328

High

1255288

MIPT3
TRAF3-interacting protein 1

2

0

High-throughput

0.328

High

1259894

CPNE4
Copine-4

2

0

High-throughput

0.328

High

1259898

ZN496
Zinc finger protein 496

2

0

High-throughput

0.328

High

1259931

NGN3
Neurogenin-3

2

0

High-throughput

0.328

High

642482

RL13
Large ribosomal subunit protein eL13

2

0

High-throughput

0.318

High

649626

RL10
Large ribosomal subunit protein uL16

2

0

High-throughput

0.318

High

997425

VAC14
Protein VAC14 homolog

2

0

High-throughput

0.316

High

786740

GRIA2
Glutamate receptor 2

1

0

High-throughput

0.282

High

71192

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

180388

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

323923

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

401010

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

450664

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

515293

KPSH1
Serine/threonine-protein kinase H1

1

0

High-throughput

0.279

Low

515911

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

568514

SYN1
Synapsin-1

1

0

High-throughput

0.279

Low

672704

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

736612

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.279

Low

806609

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

899278

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

946373

GPSM2
G-protein-signaling modulator 2

1

0

High-throughput

0.279

Low

996117

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.279

Low

1054866

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1055957

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1114164

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1125207

NOM1
Nucleolar MIF4G domain-containing protein 1

1

0

High-throughput

0.279

Low

1129339

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1176042

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1238277

RGF1A
Ras-GEF domain-containing family member 1A

1

0

High-throughput

0.279

Low

1252838

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1259902

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1259908

DDX50
ATP-dependent RNA helicase DDX50

1

0

High-throughput

0.279

Low

1259910

LS14B
Protein LSM14 homolog B

1

0

High-throughput

0.279

Low

1259911

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1259919

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.279

Low

1259929

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

1259934

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.279

Low

228167

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

314363

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

385228

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

760195

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

779797

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

842135

R144A
E3 ubiquitin-protein ligase RNF144A

1

0

Small-scale

0.249

Low

1060335

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.249

Low

1066445

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1259897

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1259900

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

1259904

FEV
Protein FEV

1

0

High-throughput

0.249

Low

1259924

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.249

Low

1259928

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1259920

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

1108473

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low

1146088

Z385C
Zinc finger protein 385C

1

0

High-throughput

0.232

Low

1259918

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024