Protein: SEM5
Sex muscle abnormal protein 5

Gene: SEM5, sem-5
Organism: Caenorhabditis elegans
Interactions: 42
UniProt ID: P29355

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0005154 - epidermal growth factor receptor binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

711469

SOS
Son of sevenless homolog

3

20

High-throughput

0.852

High

234031

SRC2
Tyrosine protein-kinase src-2

3

20

High-throughput

0.847

High

711465

Q93203
ANK_REP_REGION domain-containing protein

3

20

High-throughput

0.757

High

711471

Q9TYS3
Ferritin

3

4

High-throughput

0.660

High

711444

MIG10
Abnormal cell migration protein 10

1

8

High-throughput

0.656

High

711448

DYN1
Dynamin

1

20

High-throughput

0.656

High

711456

SIP1
Stress-induced protein 1

3

8

High-throughput

0.656

High

116175

H2L2C8
Alpha-actinin, sarcomeric

3

17

High-throughput

0.639

High

711462

Q6ABG8
E3 ubiquitin-protein ligase CBL

3

20

High-throughput

0.639

High

711452

EGL15
Myoblast growth factor receptor egl-15

1

20

Small-scale

0.621

High

111196

G5ECW9
UDENN domain-containing protein

3

12

High-throughput

0.599

High

711449

P91482
RING-type domain-containing protein

3

20

High-throughput

0.599

High

711460

Q5FC73
Uncharacterized protein

3

1

High-throughput

0.583

High

711463

Q7JP60
CCDC22 N-terminal domain-containing protein

3

16

High-throughput

0.583

High

711473

Q9XVW8
ZM domain-containing protein

2

3

High-throughput

0.559

High

115870

H2L0C1
Fibronectin type-III domain-containing protein

1

11

High-throughput

0.555

High

711472

EVA1
Protein eva-1

1

2

High-throughput

0.541

High

111780

SOC1
Multisubstrate adapter protein soc-1

1

0

Small-scale

0.519

High

94744

E0R7K7
K Homology domain-containing protein

1

20

High-throughput

0.508

High

711447

TRA1
Sex-determining transformer protein 1

1

4

High-throughput

0.508

High

112482

G5EEG8
Moesin/ezrin/radixin homolog 1

1

20

High-throughput

0.481

High

112936

MIG13
Abnormal cell migration protein 13

1

3

Small-scale

0.479

High

711454

Q17795
CRIB domain-containing protein

1

20

Small-scale

0.479

High

711464

UNC53
Adapter protein unc-53

1

20

Small-scale

0.479

High

711445

ALXA
Apoptosis-linked gene 2-interacting protein X 1

1

20

High-throughput

0.464

High

711446

ECHM
Probable enoyl-CoA hydratase, mitochondrial

1

4

High-throughput

0.464

High

711467

Q9N4A9
NAD(+) kinase

1

1

High-throughput

0.464

High

711470

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

109727

G5EBP4
Moesin/ezrin/radixin homolog 1

1

20

High-throughput

0.457

High

711453

Q17350
Polyadenylate-binding protein

1

8

High-throughput

0.457

High

711455

Q19019
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.457

High

711459

Q23158
Alpha-actinin, sarcomeric

1

17

High-throughput

0.457

High

195628

O16649
Type VI secretion system protein TssA

1

1

High-throughput

0.439

High

711458

Q22059
WD_REPEATS_REGION domain-containing protein

1

6

Small-scale

0.437

High

67395

A7DT37
Type I restriction endonuclease subunit R

1

1

High-throughput

0.417

High

115696

H2L007
CCDC22 N-terminal domain-containing protein

1

7

High-throughput

0.417

High

711457

Q20771
Uncharacterized protein

1

1

High-throughput

0.417

High

711461

Q65ZB4
ZM domain-containing protein

1

3

High-throughput

0.417

High

711450

TTR5
Transthyretin-like protein 5

1

0

High-throughput

0.265

Low

711451

PUR6
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

0

High-throughput

0.265

Low

711468

Q9N582
RanBP2-type domain-containing protein

1

0

High-throughput

0.251

Low

711466

Q9BKP3
SHOCT domain-containing protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025