Protein: PUR6
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]

Gene: PUR6, paic-1
Organism: Caenorhabditis elegans
Interactions: 25
UniProt ID: Q10457

Gene Ontology (top 5):
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 - ATP binding
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1083051

PUR6
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

6

High-throughput

0.733

High

112325

SRC1
Tyrosine protein-kinase src-1

1

0

High-throughput

0.486

High

144845

O01661
Guanylate kinase/L-type calcium channel beta subunit domain-containing protein

1

1

High-throughput

0.464

High

758537

YKA7
Uncharacterized protein B0303.7

1

2

High-throughput

0.464

High

1083052

Q18204
SH3 domain-containing protein

1

4

High-throughput

0.464

High

1083058

Q95XW5
MAGUK family

1

1

High-throughput

0.464

High

1083059

Q9N415
Variant SH3 domain protein

1

1

High-throughput

0.464

High

1083060

CED2
Cell death abnormality protein 2

1

2

High-throughput

0.464

High

1083061

Q9U2T9
Intersectin-1

1

1

High-throughput

0.464

High

110299

ARK1
Ack-related non-receptor tyrosine kinase

1

2

High-throughput

0.457

High

112774

G5EEQ7
SH3 domain-containing protein

1

1

High-throughput

0.439

High

1083056

Q86DC0
SAM domain-containing protein

1

1

High-throughput

0.439

High

3187

MLK1
Mitogen-activated protein kinase kinase kinase mlk-1

1

0

High-throughput

0.438

High

110891

G5ECK4
SH3 domain-containing GRB2-like protein

1

2

High-throughput

0.417

High

1083053

Q18662
Caskin-2

1

3

High-throughput

0.417

High

109070

G4RZC8
PID domain-containing protein

1

0

High-throughput

0.265

Low

113142

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.265

Low

196649

NPHP1
Nephrocystin-1-like protein

1

0

High-throughput

0.265

Low

711451

SEM5
Sex muscle abnormal protein 5

1

0

High-throughput

0.265

Low

1083054

Q21004
Amphiphysin

1

0

High-throughput

0.265

Low

1083055

PLCG
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3

1

0

High-throughput

0.265

Low

1083057

Q8MQ71
SH3 domain-containing protein

1

0

High-throughput

0.265

Low

1018550

LIN53
Probable histone-binding protein lin-53

1

0

High-throughput

0.249

Low

111224

DLG1
Disks large homolog 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025