Protein: DYN1
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)

Gene: DYN1, DNM1
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q05193

Gene Ontology (top 5):
GO:0001917 - photoreceptor inner segment
GO:0003723 - RNA binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924499

GRB2
Growth factor receptor-bound protein 2

14

20

Small-scale

0.985

High

983370

DYN1
Dynamin-1

8

16

Small-scale

0.970

High

983421

SNX9
Sorting nexin-9

6

15

Small-scale

0.955

High

983418

DYN3
Dynamin-3

4

17

High-throughput

0.903

High

840672

DYN2
Dynamin-2

3

17

High-throughput

0.870

High

983373

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

3

10

Small-scale

0.854

High

983379

ITSN1
Intersectin-1

2

13

Small-scale

0.825

High

557664

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.819

High

983396

SNX33
Sorting nexin-33

2

14

Small-scale

0.802

High

522926

SRC
Proto-oncogene tyrosine-protein kinase Src

2

11

Small-scale

0.789

High

983406

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

2

20

Small-scale

0.789

High

983404

SH3G1
Endophilin-A2

2

20

Small-scale

0.778

High

883328

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

16

Small-scale

0.776

High

827736

AMPH
Amphiphysin

9

19

Small-scale

0.755

High

983387

DNMBP
Dynamin-binding protein

1

20

Small-scale

0.724

High

983403

FNBP1
Formin-binding protein 1

1

20

Small-scale

0.690

High

983383

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

Small-scale

0.683

High

131238

BIN1
Myc box-dependent-interacting protein 1

1

20

Small-scale

0.681

High

246344

SCN2B
Sodium channel subunit beta-2

3

2

High-throughput

0.667

High

983380

DGUOK
Deoxyguanosine kinase, mitochondrial

3

1

High-throughput

0.667

High

983391

LYPD6
Ly6/PLAUR domain-containing protein 6

3

2

High-throughput

0.667

High

983411

KTU
Protein kintoun

3

2

High-throughput

0.667

High

983415

NUFP1
FMR1-interacting protein NUFIP1

3

2

High-throughput

0.667

High

983392

NOSTN
Nostrin

1

20

Small-scale

0.665

High

960273

CDK5
Cyclin-dependent kinase 5

1

3

Small-scale

0.647

High

972456

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

7

Small-scale

0.647

High

983416

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

20

Small-scale

0.647

High

983417

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

20

Small-scale

0.647

High

496899

TAU
Microtubule-associated protein tau

2

11

High-throughput

0.628

High

983395

TBC15
TBC1 domain family member 15

2

3

High-throughput

0.628

High

983410

S39A9
Zinc transporter ZIP9

2

1

High-throughput

0.628

High

983405

SH3G2
Endophilin-A1

2

20

Small-scale

0.619

High

209034

NCK2
Cytoplasmic protein NCK2

1

20

Small-scale

0.618

High

337437

ABL1
Tyrosine-protein kinase ABL1

1

11

High-throughput

0.618

High

384691

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.618

High

983371

FAK1
Focal adhesion kinase 1

1

14

Small-scale

0.618

High

983372

MYO1E
Unconventional myosin-Ie

1

3

Small-scale

0.618

High

983374

FAK2
Protein-tyrosine kinase 2-beta

1

17

Small-scale

0.618

High

983382

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.618

High

983399

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.618

High

983407

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.618

High

983413

SH3B4
SH3 domain-binding protein 4

1

1

Small-scale

0.618

High

118281

HAX1
HCLS1-associated protein X-1

3

1

High-throughput

0.609

High

983377

LASP1
LIM and SH3 domain protein 1

1

20

Small-scale

0.575

High

983409

TMM9B
Transmembrane protein 9B

2

6

High-throughput

0.574

High

983402

SPTCS
Spatacsin

2

0

Small-scale

0.566

High

394579

A4
Amyloid-beta precursor protein

1

2

Small-scale

0.554

High

983401

AURKB
Aurora kinase B

1

2

High-throughput

0.553

High

928072

SUMO1
Small ubiquitin-related modifier 1

1

3

Small-scale

0.541

High

317233

PCNT
Pericentrin

1

4

High-throughput

0.541

High

821845

HSP13
Heat shock 70 kDa protein 13

1

9

High-throughput

0.541

High

217309

TYOBP
TYRO protein tyrosine kinase-binding protein

1

2

High-throughput

0.536

High

362188

GLPA
Glycophorin-A

1

5

High-throughput

0.536

High

364868

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

702214

CD70
CD70 antigen

1

1

High-throughput

0.536

High

726165

BASI
Basigin

1

2

High-throughput

0.536

High

849534

GPM6A
Neuronal membrane glycoprotein M6-a

1

2

High-throughput

0.536

High

856368

EFNA4
Ephrin-A4

1

6

High-throughput

0.536

High

983398

AQP3
Aquaporin-3

1

10

High-throughput

0.536

High

327930

FTCD
Formimidoyltransferase-cyclodeaminase

1

0

High-throughput

0.518

High

983414

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.518

High

983419

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.518

High

983376

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

High-throughput

0.515

High

827173

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.513

High

983378

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

983408

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

983397

ASB13
Ankyrin repeat and SOCS box protein 13

1

2

High-throughput

0.494

High

67754

ZBBX
Zinc finger B-box domain-containing protein 1

1

2

High-throughput

0.489

High

217086

NKG2F
NKG2-F type II integral membrane protein

1

2

High-throughput

0.489

High

224926

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

983384

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

2

High-throughput

0.489

High

983385

ANR22
Ankyrin repeat domain-containing protein 22

1

4

High-throughput

0.489

High

983386

ASCL4
Achaete-scute homolog 4

1

1

High-throughput

0.489

High

983390

AMGO1
Amphoterin-induced protein 1

1

3

High-throughput

0.489

High

983412

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

6

High-throughput

0.489

High

278060

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

Small-scale

0.481

High

930160

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.481

High

983375

EPN4
Clathrin interactor 1

1

0

Small-scale

0.480

High

443470

VIME
Vimentin

1

1

High-throughput

0.479

High

455351

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

537280

DRD2
D(2) dopamine receptor

1

3

Small-scale

0.479

High

548900

NDKA
Nucleoside diphosphate kinase A

1

5

Small-scale

0.479

High

575394

EGR1
Early growth response protein 1

1

2

Small-scale

0.479

High

807696

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.479

High

983388

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

667679

NOS3
Nitric oxide synthase 3

1

0

Small-scale

0.458

High

791500

HD
Huntingtin

1

4

High-throughput

0.457

High

983381

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.457

High

720286

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

983389

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

1

Small-scale

0.437

High

983422

CABIN
Calcineurin-binding protein cabin-1

1

1

Small-scale

0.437

High

983420

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.282

High

983394

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

983400

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.279

Low

983393

U2D2L
Putative ubiquitin-conjugating enzyme E2 D2-like protein

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024