Protein: RMP
Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)

Gene: RMP, URI1
Organism: Homo sapiens
Interactions: 151
UniProt ID: O94763

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0001558 - regulation of cell growth
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

295688

UXT
Protein UXT

7

1

Small-scale

0.967

High

295690

PFD2
Prefoldin subunit 2

9

4

Small-scale

0.967

High

171565

PFD6
Prefoldin subunit 6

5

5

Small-scale

0.915

High

295681

PDRG1
p53 and DNA damage-regulated protein 1

4

1

Small-scale

0.873

High

295573

RMP
Unconventional prefoldin RPB5 interactor 1

2

1

Small-scale

0.768

High

295602

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

10

9

Small-scale

0.756

High

295613

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

9

9

Small-scale

0.755

High

295694

RUVB1
RuvB-like 1

9

2

Small-scale

0.752

High

295671

RPAP3
RNA polymerase II-associated protein 3

9

4

Small-scale

0.751

High

295693

RUVB2
RuvB-like 2

9

2

Small-scale

0.751

High

295588

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

11

0

Small-scale

0.724

High

295685

PIHD1
PIH1 domain-containing protein 1

9

0

Small-scale

0.718

High

295661

PFD5
Prefoldin subunit 5

2

0

Small-scale

0.716

High

295592

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

2

Small-scale

0.706

High

295680

PFD4
Prefoldin subunit 4

1

3

High-throughput

0.691

High

169753

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

1

Small-scale

0.686

High

295574

RPA1
DNA-directed RNA polymerase I subunit RPA1

4

2

Small-scale

0.686

High

295683

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

2

Small-scale

0.686

High

295658

DAA10
Dynein axonemal assembly factor 10

5

0

Small-scale

0.672

High

295608

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

3

1

High-throughput

0.667

High

295614

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

3

9

Small-scale

0.667

High

295645

SKAP1
Src kinase-associated phosphoprotein 1

3

1

High-throughput

0.667

High

295682

RPC5
DNA-directed RNA polymerase III subunit RPC5

4

0

Small-scale

0.664

High

295648

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

4

0

High-throughput

0.657

High

295594

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

2

High-throughput

0.656

High

155972

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

2

Small-scale

0.640

High

295589

SCP2
Sterol carrier protein 2

3

0

High-throughput

0.638

High

295625

TEBP
Prostaglandin E synthase 3

3

0

High-throughput

0.638

High

295578

RPC4
DNA-directed RNA polymerase III subunit RPC4

3

0

Small-scale

0.628

High

295607

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

0

Small-scale

0.628

High

295640

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

1

High-throughput

0.611

High

295696

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

2

High-throughput

0.611

High

295670

ASB7
Ankyrin repeat and SOCS box protein 7

2

0

High-throughput

0.602

High

282790

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

7

High-throughput

0.586

High

295585

T2FB
General transcription factor IIF subunit 2

2

0

Small-scale

0.585

High

295609

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

0

High-throughput

0.585

High

295618

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.585

High

295587

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

1

High-throughput

0.584

High

295636

PRP8
Pre-mRNA-processing-splicing factor 8

2

1

High-throughput

0.584

High

295679

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

2

Small-scale

0.584

High

295678

DMAP1
DNA methyltransferase 1-associated protein 1

1

1

Small-scale

0.573

High

295691

GPN3
GPN-loop GTPase 3

2

1

Small-scale

0.558

High

174498

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

Small-scale

0.554

High

295586

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

0

High-throughput

0.537

High

295604

GRK6
G protein-coupled receptor kinase 6

1

1

High-throughput

0.536

High

295606

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

295637

PKN3
Serine/threonine-protein kinase N3

1

2

High-throughput

0.536

High

295639

KSR2
Kinase suppressor of Ras 2

1

1

High-throughput

0.536

High

295654

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.536

High

295669

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.536

High

132001

VMA5A
von Willebrand factor A domain-containing protein 5A

1

0

High-throughput

0.513

High

195871

TTI1
TELO2-interacting protein 1 homolog

1

0

Small-scale

0.513

High

295580

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.513

High

295583

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

295627

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

295655

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

295657

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.513

High

295684

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.513

High

295699

COPG1
Coatomer subunit gamma-1

1

0

High-throughput

0.513

High

295599

T2FA
General transcription factor IIF subunit 1

1

0

Small-scale

0.512

High

295591

KS6B1
Ribosomal protein S6 kinase beta-1

1

1

Small-scale

0.501

High

295596

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.501

High

295605

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.501

High

295656

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

High-throughput

0.501

High

295577

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

118658

AIP
AH receptor-interacting protein

1

2

High-throughput

0.479

High

125060

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.479

High

156630

PPE2
Serine/threonine-protein phosphatase with EF-hands 2

1

10

High-throughput

0.479

High

162277

XPO1
Exportin-1

1

1

High-throughput

0.479

High

259906

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.479

High

272460

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

294216

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

295575

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.479

High

295598

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

295601

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.479

High

295603

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.479

High

295610

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

295611

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

295615

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

295616

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

4

Small-scale

0.479

High

295619

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

Small-scale

0.479

High

295620

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.479

High

295622

TIF1B
Transcription intermediary factor 1-beta

1

1

Small-scale

0.479

High

295623

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

295630

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

295631

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.479

High

295641

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

295642

SPT6H
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

295652

TSC1
Hamartin

1

1

High-throughput

0.479

High

295660

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.479

High

295662

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

2

High-throughput

0.479

High

295663

MEP50
Methylosome protein WDR77

1

6

High-throughput

0.479

High

295673

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.479

High

295674

Q9HAV2
Heat shock transcription factor 1

1

1

High-throughput

0.479

High

295676

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.479

High

295687

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

2

High-throughput

0.479

High

295698

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

1

High-throughput

0.479

High

73108

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

0

High-throughput

0.458

High

130671

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

173546

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

179499

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

181371

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

243227

DNJA2
DnaJ homolog subfamily A member 2

1

0

Small-scale

0.458

High

270168

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

295576

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.458

High

295579

K1C18
Keratin, type I cytoskeletal 18

1

0

Small-scale

0.458

High

295593

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

Small-scale

0.458

High

295595

METK2
S-adenosylmethionine synthase isoform type-2

1

0

Small-scale

0.458

High

295597

1433B
14-3-3 protein beta/alpha

1

0

Small-scale

0.458

High

295612

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

295621

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

295624

KEAP1
Kelch-like ECH-associated protein 1

1

0

Small-scale

0.458

High

295626

PCBP2
Poly(rC)-binding protein 2

1

0

Small-scale

0.458

High

295628

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

295643

DET1
DET1 homolog

1

0

High-throughput

0.458

High

295644

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

Small-scale

0.458

High

295646

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

295653

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

295664

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.458

High

295666

NOC4L
Nucleolar complex protein 4 homolog

1

0

Small-scale

0.458

High

295668

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

295672

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

295675

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

295686

TBCD7
TBC1 domain family member 7

1

0

High-throughput

0.458

High

295695

NOP58
Nucleolar protein 58

1

0

Small-scale

0.458

High

295697

PKP3
Plakophilin-3

1

0

Small-scale

0.458

High

295617

ACTA
Actin, aortic smooth muscle

1

2

Small-scale

0.445

High

295635

CDC73
Parafibromin

1

1

Small-scale

0.445

High

295638

CTR9
RNA polymerase-associated protein CTR9 homolog

1

2

Small-scale

0.445

High

295584

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

295590

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.437

High

295581

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

295600

MYH9
Myosin-9

1

0

Small-scale

0.426

High

295649

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.426

High

295650

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.426

High

295677

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.426

High

295692

STAP1
Signal-transducing adaptor protein 1

1

0

Small-scale

0.426

High

295582

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.407

High

67750

ZBBX
Zinc finger B-box domain-containing protein 1

2

0

High-throughput

0.328

High

295632

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

295651

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

295665

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

295689

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.269

Low

159306

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

295629

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.249

Low

295633

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.249

Low

295634

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

295647

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

295659

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

295667

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024