Protein: SHKB1
SH3KBP1-binding protein 1 (SETA-binding protein 1)

Gene: SHKB1, SHKBP1
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q8TBC3

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0042802 - identical protein binding
GO:0045742 - positive regulation of epidermal growth factor receptor signaling pathway
GO:0051260 - protein homooligomerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1252650

KCTD3
BTB/POZ domain-containing protein KCTD3

2

18

High-throughput

0.811

High

1252618

SHKB1
SH3KBP1-binding protein 1

2

16

High-throughput

0.783

High

1121246

KLH22
Kelch-like protein 22

1

4

High-throughput

0.691

High

1252629

KCTD7
BTB/POZ domain-containing protein KCTD7

1

16

High-throughput

0.691

High

1042096

CUL3
Cullin-3

7

20

Small-scale

0.678

High

904894

1433G
14-3-3 protein gamma

4

13

High-throughput

0.638

High

640261

PTN3
Tyrosine-protein phosphatase non-receptor type 3

4

9

High-throughput

0.636

High

599695

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

7

High-throughput

0.628

High

603209

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

3

1

High-throughput

0.609

High

1044662

FHL3
Four and a half LIM domains protein 3

3

2

High-throughput

0.609

High

1252633

WDR83
WD repeat domain-containing protein 83

3

6

High-throughput

0.609

High

1252638

EPN3
Epsin-3

3

6

High-throughput

0.609

High

1252649

ARI1
E3 ubiquitin-protein ligase ARIH1

3

7

High-throughput

0.609

High

982306

1433F
14-3-3 protein eta

3

13

High-throughput

0.604

High

1252625

SH3K1
SH3 domain-containing kinase-binding protein 1

3

9

Small-scale

0.604

High

683559

1433B
14-3-3 protein beta/alpha

2

13

High-throughput

0.574

High

896153

UBC12
NEDD8-conjugating enzyme Ubc12

2

8

High-throughput

0.574

High

1252637

ASPC1
Tether containing UBX domain for GLUT4

2

2

High-throughput

0.574

High

1252646

FEM1B
Protein fem-1 homolog B

2

7

High-throughput

0.574

High

979330

UBXN1
UBX domain-containing protein 1

2

10

High-throughput

0.558

High

1132910

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

20

High-throughput

0.558

High

1252628

SNX27
Sorting nexin-27

2

20

High-throughput

0.558

High

507139

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.536

High

370059

ESR1
Estrogen receptor

2

9

High-throughput

0.521

High

1252630

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

153935

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

High-throughput

0.489

High

243514

DNJA2
DnaJ homolog subfamily A member 2

1

5

High-throughput

0.489

High

276262

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.489

High

311734

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

2

High-throughput

0.489

High

323913

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

335287

DYR
Dihydrofolate reductase

1

1

High-throughput

0.489

High

663984

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

8

High-throughput

0.489

High

718037

BMI1
Polycomb complex protein BMI-1

1

6

High-throughput

0.489

High

734981

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

1

High-throughput

0.489

High

921353

RBX1
E3 ubiquitin-protein ligase RBX1

1

6

High-throughput

0.489

High

1050010

SCRIB
Protein scribble homolog

1

20

High-throughput

0.489

High

1075432

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.489

High

1079546

NEDD8
NEDD8

1

2

High-throughput

0.489

High

1100095

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1232304

MTURN
Maturin

1

4

High-throughput

0.489

High

1232935

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1233114

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.489

High

1252620

FBLI1
Filamin-binding LIM protein 1

1

6

High-throughput

0.489

High

1252623

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.489

High

1252626

DCNL1
DCN1-like protein 1

1

4

High-throughput

0.489

High

1252647

AT7L1
Ataxin-7-like protein 1

1

4

High-throughput

0.489

High

1184915

CSN6
COP9 signalosome complex subunit 6

1

4

High-throughput

0.470

High

476086

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.457

High

924719

GRB2
Growth factor receptor-bound protein 2

1

12

Small-scale

0.457

High

377517

GCR
Glucocorticoid receptor

1

8

Small-scale

0.439

High

1038003

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.439

High

163031

XPO1
Exportin-1

1

10

High-throughput

0.437

High

166979

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

4

High-throughput

0.437

High

545512

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.437

High

608054

FGFR4
Fibroblast growth factor receptor 4

1

7

High-throughput

0.437

High

684222

1433S
14-3-3 protein sigma

1

13

High-throughput

0.437

High

894236

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.437

High

906033

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.437

High

909838

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.437

High

925453

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.437

High

1168593

SYNE3
Nesprin-3

1

5

High-throughput

0.437

High

1192485

CNTRL
Centriolin

1

8

High-throughput

0.437

High

1218155

CEP97
Centrosomal protein of 97 kDa

1

11

Small-scale

0.437

High

1252621

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

2

High-throughput

0.437

High

1252622

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1252631

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.437

High

1252632

LZTS2
Leucine zipper putative tumor suppressor 2

1

11

High-throughput

0.437

High

1252635

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.437

High

1252636

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.437

High

1252639

RHOJ
Rho-related GTP-binding protein RhoJ

1

11

High-throughput

0.437

High

1252640

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

1252641

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.437

High

1252642

PKHA5
Pleckstrin homology domain-containing family A member 5

1

9

Small-scale

0.437

High

1252648

NINL
Ninein-like protein

1

3

High-throughput

0.437

High

970676

CO7A1
Collagen alpha-1(VII) chain

1

3

High-throughput

0.417

High

67916

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

20

High-throughput

0.407

High

1131777

CE170
Centrosomal protein of 170 kDa

1

3

High-throughput

0.407

High

1169878

PKHG7
Pleckstrin homology domain-containing family G member 7

1

4

High-throughput

0.407

High

1252645

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

1

High-throughput

0.407

High

1252627

TET5A
Terminal nucleotidyltransferase 5A

2

0

High-throughput

0.328

High

1252643

GLTP
Glycolipid transfer protein

2

0

High-throughput

0.328

High

202491

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.316

High

1252634

LXN
Latexin

2

0

High-throughput

0.316

High

180067

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.279

Low

225002

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

245718

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

277334

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

327295

NOE2
Noelin-2

1

0

High-throughput

0.279

Low

341451

FA12
Coagulation factor XII

1

0

High-throughput

0.279

Low

535889

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.279

Low

945812

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.279

Low

996116

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.279

Low

1128345

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.279

Low

1219943

BBS7
Bardet-Biedl syndrome 7 protein

1

0

High-throughput

0.279

Low

1252619

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.279

Low

1252624

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.279

Low

1252651

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.279

Low

851787

CCNG1
Cyclin-G1

1

0

High-throughput

0.251

Low

591027

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

1089535

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

0

High-throughput

0.249

Low

1168794

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.249

Low

1252644

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.249

Low

200633

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

484531

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024