Protein: EFNB2
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)

Gene: EFNB2
Organism: Homo sapiens
Interactions: 123
UniProt ID: P52799

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001945 - lymph vessel development
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0005886 - plasma membrane
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

856509

EPHB4
Ephrin type-B receptor 4

5

20

Small-scale

0.932

High

665565

EPHB2
Ephrin type-B receptor 2

5

20

Small-scale

0.926

High

856507

EPHB3
Ephrin type-B receptor 3

3

20

High-throughput

0.861

High

856508

EPHA5
Ephrin type-A receptor 5

3

20

High-throughput

0.861

High

856526

EFNB1
Ephrin-B1

3

5

High-throughput

0.861

High

665381

EPHA3
Ephrin type-A receptor 3

2

20

Small-scale

0.778

High

856510

EPHA4
Ephrin type-A receptor 4

1

20

Small-scale

0.761

High

129251

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

3

9

High-throughput

0.667

High

232819

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

3

1

High-throughput

0.667

High

669150

TYK2
Non-receptor tyrosine-protein kinase TYK2

3

7

High-throughput

0.667

High

787361

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

3

4

High-throughput

0.667

High

856531

MTMR1
Myotubularin-related protein 1

3

5

High-throughput

0.667

High

856532

DIP2A
Disco-interacting protein 2 homolog A

3

2

High-throughput

0.667

High

856533

KIF14
Kinesin-like protein KIF14

3

2

High-throughput

0.667

High

856540

PKHG4
Puratrophin-1

3

1

High-throughput

0.667

High

856556

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

3

1

High-throughput

0.667

High

856584

DYN3
Dynamin-3

3

6

High-throughput

0.667

High

856527

AT2B2
Plasma membrane calcium-transporting ATPase 2

3

0

High-throughput

0.638

High

834894

RGS3
Regulator of G-protein signaling 3

2

4

High-throughput

0.628

High

713069

SDC2
Syndecan-2

2

1

High-throughput

0.611

High

787192

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2

4

High-throughput

0.611

High

856568

PKP2
Plakophilin-2

2

3

High-throughput

0.611

High

856574

PICK1
PRKCA-binding protein

2

2

High-throughput

0.611

High

68150

F1712
Protein FAM171A2

3

1

High-throughput

0.609

High

240714

USO1
General vesicular transport factor p115

3

4

High-throughput

0.609

High

256740

CAND2
Cullin-associated NEDD8-dissociated protein 2

3

5

High-throughput

0.609

High

309455

MTMR5
Myotubularin-related protein 5

3

5

High-throughput

0.609

High

834400

EI2BB
Translation initiation factor eIF2B subunit beta

3

4

High-throughput

0.609

High

856539

TIGD5
Tigger transposable element-derived protein 5

3

1

High-throughput

0.609

High

856543

PKN3
Serine/threonine-protein kinase N3

3

2

High-throughput

0.609

High

856545

PKHH3
Pleckstrin homology domain-containing family H member 3

3

1

High-throughput

0.609

High

856550

DEN6A
Protein DENND6A

3

2

High-throughput

0.609

High

856567

MA7D2
MAP7 domain-containing protein 2

3

4

High-throughput

0.609

High

856580

DIP2B
Disco-interacting protein 2 homolog B

3

2

High-throughput

0.609

High

349998

RASK
GTPase KRas

2

14

High-throughput

0.584

High

856520

ARF6
ADP-ribosylation factor 6

2

1

High-throughput

0.584

High

237796

TSN3
Tetraspanin-3

2

3

High-throughput

0.574

High

209015

NCK2
Cytoplasmic protein NCK2

2

10

Small-scale

0.570

High

856566

RADIL
Ras-associating and dilute domain-containing protein

2

6

High-throughput

0.558

High

856582

EI2BD
Translation initiation factor eIF2B subunit delta

2

4

High-throughput

0.558

High

856546

ANR46
Ankyrin repeat domain-containing protein 46

2

2

High-throughput

0.553

High

253699

SDC3
Syndecan-3

1

2

High-throughput

0.536

High

499348

CD28
T-cell-specific surface glycoprotein CD28

1

1

High-throughput

0.536

High

856553

S39AB
Zinc transporter ZIP11

1

2

High-throughput

0.536

High

856525

RELN
Reelin

1

4

Small-scale

0.501

High

178449

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

318089

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

348589

RASN
GTPase NRas

1

14

High-throughput

0.479

High

349211

RASH
GTPase HRas

1

10

High-throughput

0.479

High

411651

LCK
Tyrosine-protein kinase Lck

1

5

High-throughput

0.479

High

433658

LYN
Tyrosine-protein kinase Lyn

1

5

High-throughput

0.479

High

506938

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

527363

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

546985

EZRI
Ezrin

1

3

High-throughput

0.479

High

564458

RHOQ
Rho-related GTP-binding protein RhoQ

1

17

High-throughput

0.479

High

566982

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

592174

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.479

High

598446

NF1
Neurofibromin

1

4

High-throughput

0.479

High

655281

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

5

High-throughput

0.479

High

669943

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

719686

RADI
Radixin

1

2

High-throughput

0.479

High

844450

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.479

High

856511

AFAD
Afadin

1

10

High-throughput

0.479

High

856512

ARL4C
ADP-ribosylation factor-like protein 4C

1

7

High-throughput

0.479

High

856514

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.479

High

856515

CDC42
Cell division control protein 42 homolog

1

16

High-throughput

0.479

High

856517

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

856518

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

856521

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

856522

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.479

High

856523

RAC1
Ras-related C3 botulinum toxin substrate 1

1

15

High-throughput

0.479

High

856524

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.479

High

856528

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

856529

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

856534

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

856536

RHOH
Rho-related GTP-binding protein RhoH

1

17

High-throughput

0.479

High

856537

OCLN
Occludin

1

1

High-throughput

0.479

High

856541

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

856544

RHDF2
Inactive rhomboid protein 2

1

2

High-throughput

0.479

High

856552

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

856554

ARL14
ADP-ribosylation factor-like protein 14

1

3

High-throughput

0.479

High

856557

PARD3
Partitioning defective 3 homolog

1

4

High-throughput

0.479

High

856559

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

9

High-throughput

0.479

High

856570

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

856571

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.479

High

856572

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.479

High

856578

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

1

High-throughput

0.479

High

856585

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

212776

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

856576

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

Small-scale

0.458

High

856583

UBQL1
Ubiquilin-1

1

0

High-throughput

0.458

High

167214

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

1

High-throughput

0.437

High

305394

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

856516

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.437

High

856530

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

5

High-throughput

0.437

High

856535

UBE3C
Ubiquitin-protein ligase E3C

1

2

High-throughput

0.437

High

856538

AR13B
ADP-ribosylation factor-like protein 13B

1

4

High-throughput

0.437

High

856547

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

856549

MA7D3
MAP7 domain-containing protein 3

1

3

High-throughput

0.437

High

856555

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

1

High-throughput

0.437

High

856561

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

856564

SAAL1
Protein SAAL1

1

1

High-throughput

0.437

High

856577

ARL15
ADP-ribosylation factor-like protein 15

1

4

High-throughput

0.437

High

856579

TM216
Transmembrane protein 216

1

1

High-throughput

0.437

High

856581

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

856587

ARL5A
ADP-ribosylation factor-like protein 5A

1

3

High-throughput

0.437

High

856558

LMBR1
Limb region 1 protein homolog

3

0

High-throughput

0.347

High

856569

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

3

0

High-throughput

0.347

High

856563

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

2

0

High-throughput

0.328

High

816501

MAOX
NADP-dependent malic enzyme

2

0

High-throughput

0.318

High

390139

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.279

Low

856548

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.279

Low

856551

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.279

Low

856573

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.279

Low

856562

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.269

Low

132437

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

856513

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

856519

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.249

Low

856542

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.249

Low

856560

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.249

Low

856565

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.249

Low

856575

AAAS
Aladin

1

0

High-throughput

0.249

Low

856586

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024