Protein: STYK1
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)

Gene: STYK1
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q6J9G0

Gene Ontology (top 5):
GO:0004713 - protein tyrosine kinase activity
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1153697

STYK1
Tyrosine-protein kinase STYK1

1

18

Small-scale

0.724

High

117902

MYO1F
Unconventional myosin-If

1

16

High-throughput

0.691

High

854236

DGKE
Diacylglycerol kinase epsilon

1

4

High-throughput

0.691

High

431956

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.660

High

438265

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.656

High

835829

GSK3B
Glycogen synthase kinase-3 beta

1

11

Small-scale

0.646

High

1153719

ASTRA
Protein Aster-A

2

3

High-throughput

0.628

High

383855

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

1084974

DREB
Drebrin

1

7

High-throughput

0.618

High

324824

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

High-throughput

0.618

High

647912

MARK3
MAP/microtubule affinity-regulating kinase 3

1

5

High-throughput

0.618

High

655397

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

665266

EPHA2
Ephrin type-A receptor 2

1

18

High-throughput

0.618

High

924641

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

1020180

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

1049979

SCRIB
Protein scribble homolog

1

20

High-throughput

0.618

High

1153701

MARK2
Serine/threonine-protein kinase MARK2

1

6

High-throughput

0.618

High

1153704

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

11

High-throughput

0.618

High

1153708

EHBP1
EH domain-binding protein 1

1

14

High-throughput

0.618

High

1153725

ERBIN
Erbin

1

20

High-throughput

0.618

High

1153727

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

6

Small-scale

0.618

High

1153743

PKHA1
Pleckstrin homology domain-containing family A member 1

1

20

High-throughput

0.618

High

1153757

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.618

High

1048604

DSG2
Desmoglein-2

2

20

High-throughput

0.611

High

1082823

CDC37
Hsp90 co-chaperone Cdc37

2

20

High-throughput

0.565

High

1153709

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

8

Small-scale

0.561

High

848869

AL3A2
Aldehyde dehydrogenase family 3 member A2

2

5

High-throughput

0.558

High

129306

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.553

High

573744

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.553

High

974094

DYST
Dystonin

1

11

High-throughput

0.553

High

985974

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.553

High

1035383

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.553

High

1153703

LRC49
Leucine-rich repeat-containing protein 49

1

20

High-throughput

0.553

High

1153742

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.553

High

393239

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.536

High

632305

TNR6
Tumor necrosis factor receptor superfamily member 6

1

14

High-throughput

0.536

High

726252

BASI
Basigin

1

19

High-throughput

0.536

High

944286

PRKDC
DNA-dependent protein kinase catalytic subunit

1

9

High-throughput

0.536

High

1153710

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

3

High-throughput

0.536

High

1153754

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

6

High-throughput

0.536

High

1135404

WLS
Protein wntless homolog

1

0

High-throughput

0.513

High

1054149

BECN1
Beclin-1

1

4

Small-scale

0.512

High

117731

MYO1C
Unconventional myosin-Ic

1

16

High-throughput

0.500

High

214604

MYO1B
Unconventional myosin-Ib

1

15

High-throughput

0.500

High

297364

MYO1D
Unconventional myosin-Id

1

16

High-throughput

0.500

High

299919

ERLN2
Erlin-2

1

6

High-throughput

0.500

High

966715

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

5

High-throughput

0.500

High

1153749

T106B
Transmembrane protein 106B

1

1

High-throughput

0.500

High

162872

XPO1
Exportin-1

1

5

High-throughput

0.489

High

229688

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

12

High-throughput

0.489

High

654432

CALX
Calnexin

1

7

High-throughput

0.489

High

838901

EMD
Emerin

1

7

High-throughput

0.489

High

901487

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.489

High

1130880

TM201
Transmembrane protein 201

1

1

High-throughput

0.489

High

1153717

NU205
Nuclear pore complex protein Nup205

1

3

High-throughput

0.489

High

1153721

RN185
E3 ubiquitin-protein ligase RNF185

1

6

High-throughput

0.489

High

1153731

T106C
Transmembrane protein 106C

1

1

High-throughput

0.489

High

1153733

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.489

High

1153750

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.489

High

1153751

NSMA3
Sphingomyelin phosphodiesterase 4

1

1

High-throughput

0.489

High

1153762

SGT1
Protein SGT1 homolog

1

7

High-throughput

0.489

High

168411

SCAM1
Secretory carrier-associated membrane protein 1

1

2

High-throughput

0.479

High

254906

CPNE3
Copine-3

1

6

High-throughput

0.479

High

280263

CBPD
Carboxypeptidase D

1

8

High-throughput

0.479

High

310678

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

11

High-throughput

0.479

High

437389

4F2
Amino acid transporter heavy chain SLC3A2

1

2

High-throughput

0.479

High

542362

PLAK
Junction plakoglobin

1

20

High-throughput

0.479

High

574699

ARF4
ADP-ribosylation factor 4

1

12

High-throughput

0.479

High

619247

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

6

High-throughput

0.479

High

841989

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

15

High-throughput

0.479

High

863249

COPB
Coatomer subunit beta

1

6

High-throughput

0.479

High

971024

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

980407

NOTC2
Neurogenic locus notch homolog protein 2

1

17

High-throughput

0.479

High

990495

CKAP4
Cytoskeleton-associated protein 4

1

11

High-throughput

0.479

High

1036421

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.479

High

1040133

STIM1
Stromal interaction molecule 1

1

7

High-throughput

0.479

High

1065474

S39AE
Metal cation symporter ZIP14

1

6

High-throughput

0.479

High

1078090

AAAT
Neutral amino acid transporter B(0)

1

8

High-throughput

0.479

High

1079348

VAMP3
Vesicle-associated membrane protein 3

1

6

High-throughput

0.479

High

1084048

OCLN
Occludin

1

7

High-throughput

0.479

High

1088373

VATF
V-type proton ATPase subunit F

1

2

High-throughput

0.479

High

1108971

ASTRB
Protein Aster-B

1

3

High-throughput

0.479

High

1138527

F1711
Protein FAM171A1

1

15

High-throughput

0.479

High

1153705

UNC5B
Netrin receptor UNC5B

1

13

High-throughput

0.479

High

1153711

NBEA
Neurobeachin

1

14

High-throughput

0.479

High

1153712

VANG1
Vang-like protein 1

1

9

High-throughput

0.479

High

1153713

DLG5
Disks large homolog 5

1

18

High-throughput

0.479

High

1153718

US6NL
USP6 N-terminal-like protein

1

13

High-throughput

0.479

High

1153735

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.479

High

1153737

S38A1
Sodium-coupled neutral amino acid symporter 1

1

2

High-throughput

0.479

High

1153738

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

6

High-throughput

0.479

High

1153745

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

1153746

JPH1
Junctophilin-1

1

8

High-throughput

0.479

High

1153747

WDR6
tRNA

1

13

High-throughput

0.479

High

1153755

DNJB4
DnaJ homolog subfamily B member 4

1

9

High-throughput

0.479

High

1153760

NISCH
Nischarin

1

19

High-throughput

0.479

High

1153764

S4A7
Sodium bicarbonate cotransporter 3

1

2

High-throughput

0.479

High

1153706

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

0

High-throughput

0.458

High

1153763

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

High-throughput

0.458

High

130524

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

3

High-throughput

0.457

High

363520

FETUA
Alpha-2-HS-glycoprotein

1

5

High-throughput

0.457

High

1126545

MDH1B
Putative malate dehydrogenase 1B

1

2

High-throughput

0.457

High

1153707

ZN561
Zinc finger protein 561

1

4

High-throughput

0.457

High

1153715

S39A7
Zinc transporter SLC39A7

1

6

High-throughput

0.457

High

1123411

H90B4
Putative heat shock protein HSP 90-beta 4

1

20

High-throughput

0.445

High

1123480

HS905
Putative heat shock protein HSP 90-alpha A5

1

20

High-throughput

0.445

High

68184

F1712
Protein FAM171A2

1

15

High-throughput

0.437

High

119980

AP3B1
AP-3 complex subunit beta-1

1

9

High-throughput

0.437

High

149659

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.437

High

160045

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.437

High

164133

ARHGA
Rho guanine nucleotide exchange factor 10

1

20

High-throughput

0.437

High

170863

PGRC2
Membrane-associated progesterone receptor component 2

1

5

High-throughput

0.437

High

216522

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

8

High-throughput

0.437

High

273844

NU155
Nuclear pore complex protein Nup155

1

5

High-throughput

0.437

High

313550

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.437

High

315568

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.437

High

315720

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.437

High

315839

AGRL2
Adhesion G protein-coupled receptor L2

1

10

High-throughput

0.437

High

438782

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.437

High

725473

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.437

High

818958

COPD
Coatomer subunit delta

1

5

High-throughput

0.437

High

863460

COPA
Coatomer subunit alpha

1

7

High-throughput

0.437

High

929507

RACK1
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.437

High

1073964

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.437

High

1074046

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.437

High

1151763

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

2

High-throughput

0.437

High

1153698

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

10

High-throughput

0.437

High

1153702

VP13B
Intermembrane lipid transfer protein VPS13B

1

3

High-throughput

0.437

High

1153714

DEP1B
DEP domain-containing protein 1B

1

16

High-throughput

0.437

High

1153716

TBCD5
TBC1 domain family member 5

1

15

High-throughput

0.437

High

1153722

GRM2B
GRAM domain-containing protein 2B

1

3

High-throughput

0.437

High

1153723

SAHH3
Adenosylhomocysteinase 3

1

8

High-throughput

0.437

High

1153724

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.437

High

1153726

CLCC1
Chloride channel CLIC-like protein 1

1

4

High-throughput

0.437

High

1153728

CDCA3
Cell division cycle-associated protein 3

1

8

High-throughput

0.437

High

1153730

ESYT1
Extended synaptotagmin-1

1

7

High-throughput

0.437

High

1153732

RFIP5
Rab11 family-interacting protein 5

1

7

High-throughput

0.437

High

1153734

SPY4
Protein sprouty homolog 4

1

6

High-throughput

0.437

High

1153736

TANC1
Protein TANC1

1

15

High-throughput

0.437

High

1153739

GCP60
Golgi resident protein GCP60

1

12

High-throughput

0.437

High

1153741

GORS2
Golgi reassembly-stacking protein 2

1

11

High-throughput

0.437

High

1153748

VPS45
Vacuolar protein sorting-associated protein 45

1

8

High-throughput

0.437

High

1153756

TRM7
tRNA

1

6

High-throughput

0.437

High

1153758

KDIS
Kinase D-interacting substrate of 220 kDa

1

12

High-throughput

0.437

High

1153759

SAC2
Phosphatidylinositide phosphatase SAC2

1

3

High-throughput

0.437

High

1153761

MAN1
Inner nuclear membrane protein Man1

1

6

High-throughput

0.437

High

1119194

MBRL
Membralin

3

0

High-throughput

0.349

High

1153700

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.292

High

1124430

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.279

Low

1153729

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.279

Low

1153740

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1153744

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

1153753

SENP1
Sentrin-specific protease 1

1

0

High-throughput

0.279

Low

1153699

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1153720

NRBF2
Nuclear receptor-binding factor 2

1

0

Small-scale

0.249

Low

1153752

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024