Protein: AVR2A
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)

Gene: AVR2A, ACVR2A
Organism: Homo sapiens
Interactions: 96
UniProt ID: P27037

Gene Ontology (top 5):
GO:0001702 - gastrulation with mouth forming second
GO:0001934 - positive regulation of protein phosphorylation
GO:0004674 - protein serine/threonine kinase activity
GO:0004675 - transmembrane receptor protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520070

BMP2
Bone morphogenetic protein 2

6

20

Small-scale

0.939

High

439881

INHBA
Inhibin beta A chain

6

20

Small-scale

0.935

High

646019

ACV1B
Activin receptor type-1B

5

20

Small-scale

0.912

High

646023

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

4

High-throughput

0.861

High

451817

INHBB
Inhibin beta B chain

3

20

Small-scale

0.853

High

574181

BMP7
Bone morphogenetic protein 7

3

20

Small-scale

0.827

High

646054

HAVR2
Hepatitis A virus cellular receptor 2

2

3

High-throughput

0.811

High

646021

TGFR2
TGF-beta receptor type-2

2

20

High-throughput

0.789

High

646031

AVR2B
Activin receptor type-2B

2

20

Small-scale

0.789

High

646080

GDF2
Growth/differentiation factor 2

2

20

Small-scale

0.778

High

602925

BMP6
Bone morphogenetic protein 6

2

20

Small-scale

0.768

High

646020

ACVL1
Serine/threonine-protein kinase receptor R3

2

20

Small-scale

0.754

High

646030

ACVR1
Activin receptor type-1

2

20

Small-scale

0.754

High

156795

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.691

High

276227

CIB2
Calcium and integrin-binding family member 2

1

5

High-throughput

0.691

High

434138

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.691

High

646025

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.691

High

646029

CD83
CD83 antigen

1

2

High-throughput

0.691

High

646035

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

1

High-throughput

0.691

High

646039

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.691

High

646055

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

5

High-throughput

0.691

High

646086

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.691

High

312997

BMP10
Bone morphogenetic protein 10

1

20

Small-scale

0.647

High

520099

BMP4
Bone morphogenetic protein 4

1

20

Small-scale

0.647

High

646064

NODAL
Nodal homolog

1

20

Small-scale

0.647

High

646058

MRAP2
Melanocortin-2 receptor accessory protein 2

2

5

High-throughput

0.628

High

646082

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.618

High

396834

INHA
Inhibin alpha chain

1

20

Small-scale

0.618

High

564416

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

646018

BMR1A
Bone morphogenetic protein receptor type-1A

1

20

Small-scale

0.618

High

646022

GDF5
Growth/differentiation factor 5

1

20

Small-scale

0.618

High

646032

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.618

High

646040

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

170530

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

1

High-throughput

0.609

High

571087

EGLN
Endoglin

2

12

Small-scale

0.584

High

239792

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.575

High

646061

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

20

High-throughput

0.574

High

646083

RNF11
RING finger protein 11

2

14

High-throughput

0.574

High

68224

HECA2
HEPACAM family member 2

2

3

High-throughput

0.558

High

646070

GINM1
Glycoprotein integral membrane protein 1

2

2

High-throughput

0.558

High

646026

SYJ2B
Synaptojanin-2-binding protein

2

4

Small-scale

0.556

High

646048

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.553

High

646079

TSP50
Probable threonine protease PRSS50

1

3

Small-scale

0.552

High

121446

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

7

High-throughput

0.536

High

179144

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.536

High

237469

TLR2
Toll-like receptor 2

1

20

High-throughput

0.536

High

301026

SLIK3
SLIT and NTRK-like protein 3

1

20

High-throughput

0.536

High

444669

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

3

High-throughput

0.536

High

565999

INAR1
Interferon alpha/beta receptor 1

1

11

High-throughput

0.536

High

646036

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.536

High

646041

KCNKI
Potassium channel subfamily K member 18

1

5

High-throughput

0.536

High

646043

DAAM2
Disheveled-associated activator of morphogenesis 2

1

3

High-throughput

0.536

High

646044

T150A
Transmembrane protein 150A

1

1

High-throughput

0.536

High

646047

TCAM2
TIR domain-containing adapter molecule 2

1

1

High-throughput

0.536

High

646051

RN149
E3 ubiquitin-protein ligase RNF149

1

11

High-throughput

0.536

High

646053

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

8

High-throughput

0.536

High

646056

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

5

High-throughput

0.536

High

646060

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

3

High-throughput

0.536

High

646062

OPALI
Opalin

1

3

High-throughput

0.536

High

646066

PCDC1
Protocadherin alpha-C1

1

5

High-throughput

0.536

High

646067

CRLF2
Cytokine receptor-like factor 2

1

5

High-throughput

0.536

High

646069

CP26B
Cytochrome P450 26B1

1

1

High-throughput

0.536

High

646072

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

646073

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

1

20

High-throughput

0.536

High

646075

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

8

High-throughput

0.536

High

646076

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

2

High-throughput

0.536

High

646077

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

7

High-throughput

0.536

High

646081

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

4

High-throughput

0.536

High

646085

PCDB3
Protocadherin beta-3

1

4

High-throughput

0.536

High

646087

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

5

High-throughput

0.536

High

646063

ERBIN
Erbin

1

20

Small-scale

0.527

High

539778

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.513

High

646028

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

646037

TRML2
Trem-like transcript 2 protein

1

0

High-throughput

0.513

High

646052

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

646078

DAXX
Death domain-associated protein 6

1

1

Small-scale

0.508

High

526876

TDGF1
Protein Cripto

1

7

Small-scale

0.501

High

646017

CALX
Calnexin

1

4

High-throughput

0.489

High

646027

CTXN1
Cortexin-1

1

1

High-throughput

0.489

High

646034

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

2

High-throughput

0.489

High

646042

CLC14
C-type lectin domain family 14 member A

1

1

High-throughput

0.489

High

646049

NRSN1
Neurensin-1

1

2

High-throughput

0.489

High

646059

RUSF1
RUS family member 1

1

3

High-throughput

0.489

High

646068

TMM9B
Transmembrane protein 9B

1

3

High-throughput

0.489

High

646071

EVA1B
Protein eva-1 homolog B

1

2

High-throughput

0.489

High

646046

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

12

Small-scale

0.481

High

646038

RGMB
Repulsive guidance molecule B

1

6

Small-scale

0.479

High

646045

PEG10
Retrotransposon-derived protein PEG10

1

8

Small-scale

0.479

High

646050

IGSF1
Immunoglobulin superfamily member 1

1

7

Small-scale

0.479

High

646065

MAGT1
Magnesium transporter protein 1

1

1

High-throughput

0.479

High

646084

TRAF6
TNF receptor-associated factor 6

1

6

Small-scale

0.479

High

646033

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

646024

LEG7
Galectin-7

1

0

High-throughput

0.426

High

513732

CP19A
Aromatase

1

0

High-throughput

0.279

Low

646057

F131C
Protein FAM131C

1

0

High-throughput

0.279

Low

646074

AKA7G
A-kinase anchor protein 7 isoform gamma

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024