Protein: DUS14
Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6)

Gene: DUS14, DUSP14
Organism: Homo sapiens
Interactions: 172
UniProt ID: O95147

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004725 - protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0016311 - dephosphorylation
GO:0017017 - MAP kinase tyrosine/serine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

304933

MK09
Mitogen-activated protein kinase 9

3

20

High-throughput

0.861

High

305001

IL31R
Interleukin-31 receptor subunit alpha

2

2

High-throughput

0.726

High

305014

OTUL
Ubiquitin thioesterase otulin

3

1

High-throughput

0.667

High

305010

TFG
Protein TFG

3

0

High-throughput

0.638

High

305008

FAN
Protein FAN

2

1

High-throughput

0.628

High

304908

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.625

High

304915

EPHA1
Ephrin type-A receptor 1

1

20

High-throughput

0.625

High

304919

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.625

High

304954

TRAF2
TNF receptor-associated factor 2

2

7

Small-scale

0.624

High

304940

DUS3
Dual specificity protein phosphatase 3

1

19

High-throughput

0.618

High

304972

TENS2
Tensin-2

1

1

High-throughput

0.618

High

305029

O51E2
Olfactory receptor 51E2

3

1

High-throughput

0.609

High

304985

GPBP1
Vasculin

2

0

High-throughput

0.602

High

305015

F136A
Protein FAM136A

2

0

High-throughput

0.602

High

305031

HEAT1
HEAT repeat-containing protein 1

2

0

High-throughput

0.602

High

305048

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.602

High

305013

FUBP2
Far upstream element-binding protein 2

2

9

High-throughput

0.601

High

178939

FOXP2
Forkhead box protein P2

2

1

High-throughput

0.574

High

304904

MAS
Proto-oncogene Mas

2

2

High-throughput

0.574

High

304959

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

2

1

High-throughput

0.574

High

304973

LPCT4
Lysophospholipid acyltransferase LPCAT4

2

2

High-throughput

0.574

High

304986

RFIP4
Rab11 family-interacting protein 4

2

6

High-throughput

0.574

High

305003

GRP4
RAS guanyl-releasing protein 4

2

1

High-throughput

0.574

High

305019

RM38
Large ribosomal subunit protein mL38

2

1

High-throughput

0.574

High

305028

RHBT2
Rho-related BTB domain-containing protein 2

2

5

High-throughput

0.574

High

305043

FBXL4
F-box/LRR-repeat protein 4

2

2

High-throughput

0.574

High

305045

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

2

1

High-throughput

0.574

High

305053

KIF3A
Kinesin-like protein KIF3A

2

4

High-throughput

0.574

High

304921

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

1

High-throughput

0.558

High

304955

COASY
Bifunctional coenzyme A synthase

2

1

High-throughput

0.558

High

304962

RB11B
Ras-related protein Rab-11B

2

1

High-throughput

0.558

High

304984

P2RY8
P2Y purinoceptor 8

2

1

High-throughput

0.558

High

305016

P5CR2
Pyrroline-5-carboxylate reductase 2

2

1

High-throughput

0.558

High

153517

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.554

High

304907

INSR
Insulin receptor

1

20

High-throughput

0.553

High

304916

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.541

High

304949

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.541

High

266878

SRS10
Serine/arginine-rich splicing factor 10

1

7

High-throughput

0.536

High

304898

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

High-throughput

0.536

High

304923

RYK
Tyrosine-protein kinase RYK

1

19

High-throughput

0.536

High

304939

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

3

High-throughput

0.536

High

304980

DYM
Dymeclin

1

1

High-throughput

0.536

High

305027

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

1

High-throughput

0.536

High

305030

SRMS
Tyrosine-protein kinase Srms

1

7

High-throughput

0.536

High

305041

NOCT
Nocturnin

1

1

High-throughput

0.536

High

305042

FBX3
F-box only protein 3

1

1

High-throughput

0.536

High

305052

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

High-throughput

0.536

High

305034

INO1
Inositol-3-phosphate synthase 1

1

0

High-throughput

0.518

High

242957

EDF1
Endothelial differentiation-related factor 1

1

0

High-throughput

0.513

High

277163

TNF13
Tumor necrosis factor ligand superfamily member 13

1

0

High-throughput

0.513

High

281973

ANXA9
Annexin A9

1

0

High-throughput

0.513

High

304900

LGI1
Leucine-rich glioma-inactivated protein 1

1

0

High-throughput

0.513

High

304914

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

304920

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

304924

PROF2
Profilin-2

1

0

High-throughput

0.513

High

304977

NPSR1
Neuropeptide S receptor

1

0

High-throughput

0.513

High

304978

HEPN1
Putative cancer susceptibility gene HEPN1 protein

1

0

High-throughput

0.513

High

304999

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.513

High

305021

DTBP1
Dysbindin

1

0

High-throughput

0.513

High

305032

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.513

High

305049

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

0

High-throughput

0.513

High

304905

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.494

High

304917

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.494

High

304950

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.494

High

304956

PTK7
Inactive tyrosine-protein kinase 7

1

12

High-throughput

0.494

High

304961

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.494

High

304979

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

304988

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

119898

AP3B1
AP-3 complex subunit beta-1

1

1

High-throughput

0.489

High

127082

FOXN3
Forkhead box protein N3

1

2

High-throughput

0.489

High

304934

CAZA2
F-actin-capping protein subunit alpha-2

1

4

High-throughput

0.489

High

304935

RGR
RPE-retinal G protein-coupled receptor

1

1

High-throughput

0.489

High

304971

TMTC4
Protein O-mannosyl-transferase TMTC4

1

3

High-throughput

0.489

High

304976

WDR59
GATOR2 complex protein WDR59

1

1

High-throughput

0.489

High

304982

DSG4
Desmoglein-4

1

3

High-throughput

0.489

High

304983

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

1

High-throughput

0.489

High

304991

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

2

High-throughput

0.489

High

305011

US6NL
USP6 N-terminal-like protein

1

1

High-throughput

0.489

High

305017

RB39B
Ras-related protein Rab-39B

1

6

High-throughput

0.489

High

305025

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

3

High-throughput

0.489

High

305035

SPTC3
Serine palmitoyltransferase 3

1

1

High-throughput

0.489

High

305051

RT18C
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.489

High

305054

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.480

High

235635

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

4

High-throughput

0.479

High

304901

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

304912

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

304913

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

8

High-throughput

0.479

High

304918

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

4

High-throughput

0.479

High

304927

RBMX
RNA-binding motif protein, X chromosome

1

7

High-throughput

0.479

High

304930

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

10

High-throughput

0.479

High

304932

MATR3
Matrin-3

1

5

High-throughput

0.479

High

304936

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

304941

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

6

High-throughput

0.479

High

304945

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

9

High-throughput

0.479

High

304948

RT35
Small ribosomal subunit protein mS35

1

2

High-throughput

0.479

High

304964

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.479

High

304965

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

6

High-throughput

0.479

High

304966

Q4LE69
1-phosphatidylinositol 4-kinase

1

3

High-throughput

0.479

High

304968

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.479

High

304990

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.479

High

305002

LNX1
E3 ubiquitin-protein ligase LNX

1

6

Small-scale

0.479

High

305007

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

7

High-throughput

0.479

High

305023

FUBP3
Far upstream element-binding protein 3

1

9

High-throughput

0.479

High

305024

QKI
KH domain-containing RNA-binding protein QKI

1

3

High-throughput

0.479

High

305038

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

7

High-throughput

0.479

High

305047

UBP18
Ubl carboxyl-terminal hydrolase 18

1

10

Small-scale

0.479

High

305056

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

10

High-throughput

0.479

High

271503

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.458

High

305036

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.458

High

305037

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.458

High

305050

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.458

High

304929

PI4KA
Phosphatidylinositol 4-kinase alpha

1

3

High-throughput

0.445

High

264801

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.437

High

304899

DLGP3
Disks large-associated protein 3

1

1

High-throughput

0.437

High

304902

A2MG
Alpha-2-macroglobulin

1

2

High-throughput

0.437

High

304925

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.437

High

305000

FAD1
FAD synthase

1

1

High-throughput

0.437

High

305009

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

304910

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.426

High

274675

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

0

High-throughput

0.347

High

304967

SGO2
Shugoshin 2

3

0

High-throughput

0.347

High

304987

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.347

High

305012

PMM1
Phosphomannomutase 1

3

0

High-throughput

0.347

High

305020

MITOK
Mitochondrial potassium channel

3

0

High-throughput

0.347

High

305022

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

0

High-throughput

0.347

High

304931

GDF5
Growth/differentiation factor 5

2

0

High-throughput

0.328

High

304953

CF210
Cilia- and flagella- associated protein 210

2

0

High-throughput

0.328

High

304963

SYT16
Synaptotagmin-16

2

0

High-throughput

0.328

High

304974

IFIX
Pyrin and HIN domain-containing protein 1

2

0

High-throughput

0.328

High

304997

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

2

0

High-throughput

0.328

High

305006

CPLX3
Complexin-3

2

0

High-throughput

0.328

High

305026

SETB2
Histone-lysine N-methyltransferase SETDB2

2

0

High-throughput

0.328

High

304911

CD28
T-cell-specific surface glycoprotein CD28

1

0

Small-scale

0.299

High

304994

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.299

High

238830

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

304903

FOS
Protein c-Fos

1

0

High-throughput

0.279

Low

304906

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.279

Low

304909

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

304922

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

304926

DRD3
D(3) dopamine receptor

1

0

High-throughput

0.279

Low

304928

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

0

High-throughput

0.279

Low

304937

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

304938

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

304942

GSC
Homeobox protein goosecoid

1

0

High-throughput

0.279

Low

304943

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

304944

T2R38
Taste receptor type 2 member 38

1

0

High-throughput

0.279

Low

304946

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

0

High-throughput

0.279

Low

304952

ZN543
Zinc finger protein 543

1

0

High-throughput

0.279

Low

304957

ITAD
Integrin alpha-D

1

0

High-throughput

0.279

Low

304958

SPRL1
SPARC-like protein 1

1

0

High-throughput

0.279

Low

304960

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.279

Low

304969

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

304970

CAHM4
Calcium homeostasis modulator protein 4

1

0

High-throughput

0.279

Low

304975

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.279

Low

304981

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

304989

ORML3
ORM1-like protein 3

1

0

High-throughput

0.279

Low

304992

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

304993

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.279

Low

304996

TM35B
Transmembrane protein 35B

1

0

High-throughput

0.279

Low

304998

BHE23
Class E basic helix-loop-helix protein 23

1

0

High-throughput

0.279

Low

305004

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

305005

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.279

Low

305018

SLAF6
SLAM family member 6

1

0

High-throughput

0.279

Low

305033

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.279

Low

305039

NPAP1
Nuclear pore-associated protein 1

1

0

High-throughput

0.279

Low

305040

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

305044

NUDT5
ADP-sugar pyrophosphatase

1

0

High-throughput

0.279

Low

305046

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.279

Low

304947

RT22
Small ribosomal subunit protein mS22

1

0

High-throughput

0.249

Low

304951

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

0

High-throughput

0.249

Low

304995

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

305055

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024