Protein: HCFC2
Host cell factor 2 (HCF-2) (C2 factor)

Gene: HCFC2
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q9Y5Z7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848326

HCFC1
Host cell factor 1

4

15

Small-scale

0.892

High

1354094

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

8

8

Small-scale

0.750

High

903651

WDR5
WD repeat-containing protein 5

6

5

Small-scale

0.735

High

1070817

RBBP5
Retinoblastoma-binding protein 5

6

9

Small-scale

0.729

High

975356

KMT2A
Histone-lysine N-methyltransferase 2A

4

20

Small-scale

0.702

High

1267310

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

4

6

Small-scale

0.694

High

536560

IRF2
Interferon regulatory factor 2

3

4

High-throughput

0.675

High

123132

MEN1
Menin

4

1

Small-scale

0.672

High

165746

SET1A
Histone-lysine N-methyltransferase SETD1A

3

20

High-throughput

0.667

High

216879

CREB3
Cyclic AMP-responsive element-binding protein 3

3

2

High-throughput

0.667

High

1217468

NUDC3
NudC domain-containing protein 3

3

17

High-throughput

0.667

High

1244258

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

3

14

High-throughput

0.667

High

1328335

THAP2
THAP domain-containing protein 2

3

8

High-throughput

0.667

High

1349850

CXXC1
CXXC-type zinc finger protein 1

3

13

High-throughput

0.667

High

1357298

KMT2B
Histone-lysine N-methyltransferase 2B

3

20

High-throughput

0.667

High

175330

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

2

6

High-throughput

0.628

High

505020

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.628

High

573547

TCPA
T-complex protein 1 subunit alpha

2

10

High-throughput

0.628

High

771112

TCPZ
T-complex protein 1 subunit zeta

2

13

High-throughput

0.628

High

821479

TCPE
T-complex protein 1 subunit epsilon

2

13

High-throughput

0.628

High

826960

TCPG
T-complex protein 1 subunit gamma

2

12

High-throughput

0.628

High

843447

TCPD
T-complex protein 1 subunit delta

2

12

High-throughput

0.628

High

933691

TBA4A
Tubulin alpha-4A chain

2

1

High-throughput

0.628

High

943561

TCPB
T-complex protein 1 subunit beta

2

13

High-throughput

0.628

High

1114274

TBB8
Tubulin beta-8 chain

2

1

High-throughput

0.628

High

1266447

TCPW
T-complex protein 1 subunit zeta-2

2

14

High-throughput

0.628

High

1306762

TCPH
T-complex protein 1 subunit eta

2

13

High-throughput

0.628

High

1312016

DIDO1
Death-inducer obliterator 1

2

13

High-throughput

0.628

High

1350478

KANL3
KAT8 regulatory NSL complex subunit 3

2

1

High-throughput

0.611

High

958801

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

2

5

High-throughput

0.601

High

370823

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

1270042

ESR2
Estrogen receptor beta

2

8

High-throughput

0.571

High

1216741

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

Small-scale

0.561

High

789196

HELZ
Probable helicase with zinc finger domain

2

2

High-throughput

0.552

High

843111

TCPQ
T-complex protein 1 subunit theta

1

13

High-throughput

0.536

High

931961

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

962729

IRF9
Interferon regulatory factor 9

1

4

High-throughput

0.536

High

1022890

STRN3
Striatin-3

1

9

High-throughput

0.536

High

1077268

ZN174
Zinc finger protein 174

1

1

High-throughput

0.536

High

1087512

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1147429

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

3

High-throughput

0.536

High

1235283

NGEF
Ephexin-1

1

4

High-throughput

0.536

High

1273421

GLMN
Glomulin

1

3

High-throughput

0.536

High

1297535

ZN597
Zinc finger protein 597

1

2

High-throughput

0.536

High

1349150

UBIP1
Upstream-binding protein 1

1

1

High-throughput

0.536

High

1377480

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

3

High-throughput

0.536

High

1377825

NF2L3
Nuclear factor erythroid 2-related factor 3

1

6

High-throughput

0.536

High

1153152

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.513

High

1312219

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.513

High

1259626

THAP3
THAP domain-containing protein 3

1

8

High-throughput

0.489

High

1274568

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.489

High

1018142

GRSF1
G-rich sequence factor 1

1

4

Small-scale

0.481

High

68330

P20L1
PHD finger protein 20-like protein 1

1

5

High-throughput

0.479

High

152704

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

183181

KDM6A
Lysine-specific demethylase 6A

1

9

High-throughput

0.479

High

206865

FOXO3
Forkhead box protein O3

1

6

Small-scale

0.479

High

211288

BUB3
Mitotic checkpoint protein BUB3

1

8

High-throughput

0.479

High

266076

PSIP1
PC4 and SFRS1-interacting protein

1

1

High-throughput

0.479

High

267724

TADA3
Transcriptional adapter 3

1

1

High-throughput

0.479

High

632967

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

692205

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

734820

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.479

High

855965

ZN131
Zinc finger protein 131

1

2

High-throughput

0.479

High

869566

ATN1
Atrophin-1

1

12

High-throughput

0.479

High

918221

H4
Histone H4

1

3

High-throughput

0.479

High

1057808

NCOA6
Nuclear receptor coactivator 6

1

9

High-throughput

0.479

High

1077628

ELF2
ETS-related transcription factor Elf-2

1

5

High-throughput

0.479

High

1166740

WDR82
WD repeat-containing protein 82

1

12

High-throughput

0.479

High

1173295

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.479

High

1188212

KANL1
KAT8 regulatory NSL complex subunit 1

1

1

High-throughput

0.479

High

1223219

ZZZ3
ZZ-type zinc finger-containing protein 3

1

3

High-throughput

0.479

High

1243854

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

1244603

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

1289485

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

4

Small-scale

0.479

High

1290793

MCRS1
Microspherule protein 1

1

1

High-throughput

0.479

High

1313853

PHF20
PHD finger protein 20

1

10

High-throughput

0.479

High

1318631

DPY30
Protein dpy-30 homolog

1

1

High-throughput

0.479

High

1333264

KAT8
Histone acetyltransferase KAT8

1

1

High-throughput

0.479

High

1333511

CSR2B
Cysteine-rich protein 2-binding protein

1

5

High-throughput

0.479

High

1334375

KANL2
KAT8 regulatory NSL complex subunit 2

1

1

High-throughput

0.479

High

1345389

MBIP1
MAP3K12-binding inhibitory protein 1

1

2

High-throughput

0.479

High

1350540

RERE
Arginine-glutamic acid dipeptide repeats protein

1

10

High-throughput

0.479

High

1356856

ZN608
Zinc finger protein 608

1

3

High-throughput

0.479

High

1356952

YETS2
YEATS domain-containing protein 2

1

7

High-throughput

0.479

High

1357739

SET1B
Histone-lysine N-methyltransferase SETD1B

1

20

High-throughput

0.479

High

1377063

NUDC
Nuclear migration protein nudC

1

17

High-throughput

0.479

High

574782

ARF4
ADP-ribosylation factor 4

1

0

High-throughput

0.458

High

1256519

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1355904

CNOT7
CCR4-NOT transcription complex subunit 7

1

0

High-throughput

0.458

High

348374

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.445

High

536463

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.279

Low

1268569

K0232
Uncharacterized protein KIAA0232

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024