Protein: RU2A
U2 small nuclear ribonucleoprotein A' (U2 snRNP A')

Gene: RU2A, SNRPA1
Organism: Homo sapiens
Interactions: 240
UniProt ID: P09661

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441217

RU2B
U2 small nuclear ribonucleoprotein B''

7

10

Small-scale

0.967

High

446487

SNRPA
U1 small nuclear ribonucleoprotein A

6

12

High-throughput

0.953

High

453752

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

5

4

High-throughput

0.927

High

453789

RUXF
Small nuclear ribonucleoprotein F

4

12

High-throughput

0.909

High

453792

SMD2
Small nuclear ribonucleoprotein Sm D2

4

4

High-throughput

0.903

High

165383

SR140
U2 snRNP-associated SURP motif-containing protein

3

1

High-throughput

0.861

High

212096

HTSF1
17S U2 SnRNP complex component HTATSF1

3

5

High-throughput

0.861

High

453791

SMD1
Small nuclear ribonucleoprotein Sm D1

3

10

High-throughput

0.861

High

453793

SMD3
Small nuclear ribonucleoprotein Sm D3

3

11

High-throughput

0.861

High

453796

RSMN
Small nuclear ribonucleoprotein-associated protein N

3

4

High-throughput

0.861

High

453826

SF3B4
Splicing factor 3B subunit 4

3

3

High-throughput

0.861

High

453890

SPF45
Splicing factor 45

3

4

High-throughput

0.861

High

453942

SF3B6
Splicing factor 3B subunit 6

3

8

High-throughput

0.861

High

453790

RUXG
Small nuclear ribonucleoprotein G

3

11

High-throughput

0.847

High

453788

RUXE
Small nuclear ribonucleoprotein E

2

3

High-throughput

0.811

High

441840

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

4

High-throughput

0.789

High

453781

RBM5
RNA-binding protein 5

2

3

High-throughput

0.789

High

453819

RBM39
RNA-binding protein 39

2

4

High-throughput

0.789

High

453935

PPIE
Peptidyl-prolyl cis-trans isomerase E

2

0

High-throughput

0.770

High

453836

LARP7
La-related protein 7

2

3

High-throughput

0.754

High

453805

SF3A3
Splicing factor 3A subunit 3

7

1

Small-scale

0.746

High

453827

SF3A2
Splicing factor 3A subunit 2

7

4

Small-scale

0.746

High

453828

SF3A1
Splicing factor 3A subunit 1

6

3

High-throughput

0.733

High

268585

SF3B1
Splicing factor 3B subunit 1

5

7

High-throughput

0.718

High

453899

SF3B5
Splicing factor 3B subunit 5

5

1

High-throughput

0.718

High

453810

SF3B2
Splicing factor 3B subunit 2

4

2

High-throughput

0.699

High

453825

SF3B3
Splicing factor 3B subunit 3

4

8

High-throughput

0.699

High

453893

CDC5L
Cell division cycle 5-like protein

4

3

Small-scale

0.699

High

453913

SYF1
Pre-mRNA-splicing factor SYF1

4

11

Small-scale

0.696

High

453933

ISY1
Pre-mRNA-splicing factor ISY1 homolog

4

2

Small-scale

0.696

High

241258

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.691

High

453762

FUS
RNA-binding protein FUS

1

7

High-throughput

0.691

High

453777

RBM25
RNA-binding protein 25

1

9

High-throughput

0.691

High

453824

RNPS1
RNA-binding protein with serine-rich domain 1

1

4

High-throughput

0.691

High

453876

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

2

High-throughput

0.691

High

453920

RBM22
Pre-mRNA-splicing factor RBM22

1

7

High-throughput

0.691

High

230709

AQR
RNA helicase aquarius

3

3

High-throughput

0.667

High

236190

PRP17
Pre-mRNA-processing factor 17

3

8

High-throughput

0.667

High

327769

SYF2
Pre-mRNA-splicing factor SYF2

3

1

High-throughput

0.667

High

453753

GCFC2
Intron Large complex component GCFC2

3

1

High-throughput

0.667

High

453782

ELL
RNA polymerase II elongation factor ELL

3

2

High-throughput

0.667

High

453813

SNW1
SNW domain-containing protein 1

3

2

High-throughput

0.667

High

453833

C19L2
CWF19-like protein 2

3

3

High-throughput

0.667

High

453842

C19L1
CWF19-like protein 1

3

3

High-throughput

0.667

High

453872

GEMI5
Gem-associated protein 5

3

7

High-throughput

0.667

High

453883

ESS2
Splicing factor ESS-2 homolog

3

1

High-throughput

0.667

High

453892

TGS1
Trimethylguanosine synthase

3

1

High-throughput

0.667

High

453900

NADAP
Kanadaptin

3

6

High-throughput

0.667

High

453901

CRNL1
Crooked neck-like protein 1

3

12

High-throughput

0.667

High

345759

MYC
Myc proto-oncogene protein

3

6

High-throughput

0.640

High

305061

SPN1
Snurportin-1

3

0

High-throughput

0.638

High

453841

ICE2
Little elongation complex subunit 2

3

0

High-throughput

0.638

High

453873

CCD12
Coiled-coil domain-containing protein 12

3

0

High-throughput

0.638

High

453888

TOE1
Target of EGR1 protein 1

3

0

High-throughput

0.638

High

453908

PHAX
Phosphorylated adapter RNA export protein

3

0

High-throughput

0.638

High

453909

PKRI1
PRKR-interacting protein 1

3

0

High-throughput

0.638

High

453937

ICE1
Little elongation complex subunit 1

3

0

High-throughput

0.638

High

453847

ZC3HE
Zinc finger CCCH domain-containing protein 14

2

1

High-throughput

0.628

High

453854

PHF5A
PHD finger-like domain-containing protein 5A

2

1

High-throughput

0.628

High

453931

ACINU
Apoptotic chromatin condensation inducer in the nucleus

2

7

High-throughput

0.628

High

453758

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.618

High

453808

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.618

High

453879

RBP56
TATA-binding protein-associated factor 2N

1

5

High-throughput

0.618

High

453941

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

10

High-throughput

0.618

High

453767

BUD31
Protein BUD31 homolog

2

2

High-throughput

0.611

High

453852

DDX46
Probable ATP-dependent RNA helicase DDX46

2

4

High-throughput

0.611

High

453809

IKZF1
DNA-binding protein Ikaros

2

2

High-throughput

0.606

High

453865

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

2

High-throughput

0.606

High

453801

NCBP1
Nuclear cap-binding protein subunit 1

2

1

High-throughput

0.601

High

453763

COIL
Coilin

2

0

High-throughput

0.585

High

453932

ZN346
Zinc finger protein 346

2

0

High-throughput

0.585

High

385959

P53
Cellular tumor antigen p53

2

1

Small-scale

0.584

High

453747

HSP7C
Heat shock cognate 71 kDa protein

2

10

Small-scale

0.584

High

453853

MEPCE
7SK snRNA methylphosphate capping enzyme

2

1

High-throughput

0.584

High

453877

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

5

Small-scale

0.584

High

68398

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

11

High-throughput

0.575

High

453780

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.575

High

453748

TOP1
DNA topoisomerase 1

1

1

Small-scale

0.554

High

453755

VCAM1
Vascular cell adhesion protein 1

2

7

High-throughput

0.549

High

263484

PR40A
Pre-mRNA-processing factor 40 homolog A

1

12

High-throughput

0.536

High

448534

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

453743

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

1

7

High-throughput

0.536

High

453744

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

7

High-throughput

0.536

High

453745

H14
Histone H1.4

1

5

High-throughput

0.536

High

453757

H1T
Histone H1t

1

5

High-throughput

0.536

High

453773

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

453778

RBP2
E3 SUMO-protein ligase RanBP2

1

3

High-throughput

0.536

High

453812

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

4

High-throughput

0.536

High

453815

CUL3
Cullin-3

1

6

High-throughput

0.536

High

453830

SMN
Survival motor neuron protein

1

2

Small-scale

0.536

High

453843

KDM4D
Lysine-specific demethylase 4D

1

1

High-throughput

0.536

High

453858

ZCH18
Zinc finger CCCH domain-containing protein 18

1

5

High-throughput

0.536

High

453859

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

5

High-throughput

0.536

High

453860

SUGP1
SURP and G-patch domain-containing protein 1

1

2

High-throughput

0.536

High

453904

PININ
Pinin

1

3

High-throughput

0.536

High

453914

TF7L2
Transcription factor 7-like 2

1

8

High-throughput

0.536

High

453923

ING3
Inhibitor of growth protein 3

1

2

High-throughput

0.536

High

453925

CWC15
Spliceosome-associated protein CWC15 homolog

1

2

High-throughput

0.536

High

453927

KLHL8
Kelch-like protein 8

1

6

High-throughput

0.536

High

453928

TFP11
Tuftelin-interacting protein 11

1

3

High-throughput

0.536

High

453930

GPTC8
G patch domain-containing protein 8

1

6

High-throughput

0.536

High

453943

PAXB1
PAX3- and PAX7-binding protein 1

1

1

High-throughput

0.536

High

453924

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

High-throughput

0.530

High

453756

HNF1A
Hepatocyte nuclear factor 1-alpha

1

1

High-throughput

0.515

High

453822

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.515

High

453864

ZN276
Zinc finger protein 276

1

3

High-throughput

0.515

High

453896

TIRR
Tudor-interacting repair regulator protein

1

1

High-throughput

0.515

High

453764

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

453769

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

453770

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

453814

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

453844

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

453875

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

453886

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.513

High

453898

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

453921

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

453785

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

7

High-throughput

0.501

High

453906

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.493

High

157415

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

7

High-throughput

0.489

High

152821

TRDMT
tRNA

1

1

High-throughput

0.479

High

154733

TCRG1
Transcription elongation regulator 1

1

4

Small-scale

0.479

High

162358

XPO1
Exportin-1

1

5

High-throughput

0.479

High

232771

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

17

High-throughput

0.479

High

267857

EED
Polycomb protein EED

1

10

High-throughput

0.479

High

278906

SPF30
Survival of motor neuron-related-splicing factor 30

1

3

High-throughput

0.479

High

294292

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.479

High

313213

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.479

High

326392

SNAI1
Zinc finger protein SNAI1

1

4

High-throughput

0.479

High

337820

EGFR
Epidermal growth factor receptor

1

19

High-throughput

0.479

High

378941

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

453746

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.479

High

453749

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

453754

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

453759

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

453760

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

453761

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

453765

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.479

High

453766

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

453768

MAGA6
Melanoma-associated antigen 6

1

1

High-throughput

0.479

High

453771

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.479

High

453772

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

453779

CDK7
Cyclin-dependent kinase 7

1

4

High-throughput

0.479

High

453783

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

4

High-throughput

0.479

High

453784

FOXA1
Hepatocyte nuclear factor 3-alpha

1

5

High-throughput

0.479

High

453786

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.479

High

453787

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

453795

H4
Histone H4

1

1

High-throughput

0.479

High

453798

H31
Histone H3.1

1

2

High-throughput

0.479

High

453799

RED1
Double-stranded RNA-specific editase 1

1

4

High-throughput

0.479

High

453802

EP300
Histone acetyltransferase p300

1

10

High-throughput

0.479

High

453804

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

4

High-throughput

0.479

High

453806

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

High-throughput

0.479

High

453811

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

453817

TRI14
Tripartite motif-containing protein 14

1

4

High-throughput

0.479

High

453818

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

9

High-throughput

0.479

High

453820

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

453823

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

453831

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

453840

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

453846

PRP8
Pre-mRNA-processing-splicing factor 8

1

4

High-throughput

0.479

High

453850

MOB3C
MOB kinase activator 3C

1

6

High-throughput

0.479

High

453851

ASXL2
Putative Polycomb group protein ASXL2

1

5

High-throughput

0.479

High

453855

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

6

High-throughput

0.479

High

453856

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

453857

SLN11
Schlafen family member 11

1

1

Small-scale

0.479

High

453861

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

453862

SRRM1
Serine/arginine repetitive matrix protein 1

1

5

High-throughput

0.479

High

453867

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

453878

ESR2
Estrogen receptor beta

1

13

High-throughput

0.479

High

453881

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

453884

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.479

High

453885

MBD6
Methyl-CpG-binding domain protein 6

1

4

High-throughput

0.479

High

453895

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

453903

DDX24
ATP-dependent RNA helicase DDX24

1

5

High-throughput

0.479

High

453905

CHM4B
Charged multivesicular body protein 4b

1

4

High-throughput

0.479

High

453911

RC3H2
Roquin-2

1

6

High-throughput

0.479

High

453912

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

3

High-throughput

0.479

High

453916

ANLN
Anillin

1

2

High-throughput

0.479

High

453922

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

453926

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

453929

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

453934

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.479

High

453936

SRRM2
Serine/arginine repetitive matrix protein 2

1

7

High-throughput

0.479

High

453938

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

2

Small-scale

0.479

High

453834

DC4L1
DDB1- and CUL4-associated factor 4-like protein 1

1

1

High-throughput

0.470

High

453887

STALP
AMSH-like protease

1

1

High-throughput

0.470

High

122460

MEN1
Menin

1

0

High-throughput

0.458

High

298085

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

302822

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

316469

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

453776

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

453800

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

453807

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

453832

DUS5
Dual specificity protein phosphatase 5

1

0

High-throughput

0.458

High

453845

CDC73
Parafibromin

1

0

High-throughput

0.458

High

453868

NEIL3
Endonuclease 8-like 3

1

0

Small-scale

0.458

High

453871

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

453894

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

453897

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

453919

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

453940

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.458

High

195326

DHX15
ATP-dependent RNA helicase DHX15

1

7

High-throughput

0.445

High

401295

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

453829

SF01
Splicing factor 1

1

2

High-throughput

0.445

High

453838

ODFP2
Outer dense fiber protein 2

1

15

High-throughput

0.445

High

453839

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

16

High-throughput

0.445

High

453863

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

453902

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

167814

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.437

High

255451

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.437

High

354256

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.437

High

399953

ICAM1
Intercellular adhesion molecule 1

1

5

High-throughput

0.437

High

443280

VIME
Vimentin

1

10

High-throughput

0.437

High

453750

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

Small-scale

0.437

High

453751

ITA4
Integrin alpha-4

1

2

High-throughput

0.437

High

453774

CASP4
Caspase-4

1

1

High-throughput

0.437

High

453794

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.437

High

453797

ACTC
Actin, alpha cardiac muscle 1

1

13

High-throughput

0.437

High

453803

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

9

High-throughput

0.437

High

453821

CUL7
Cullin-7

1

2

High-throughput

0.437

High

453849

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

453869

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

453870

RBCC1
RB1-inducible coiled-coil protein 1

1

14

High-throughput

0.437

High

453874

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

453880

IGSF8
Immunoglobulin superfamily member 8

1

7

High-throughput

0.437

High

453882

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

453907

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

453917

CNGB3
Cyclic nucleotide-gated channel beta-3

1

4

High-throughput

0.437

High

453837

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

453848

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.426

High

453910

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

453775

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.408

High

453816

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.407

High

453891

CEP63
Centrosomal protein of 63 kDa

1

12

High-throughput

0.407

High

453866

GPT11
G patch domain-containing protein 11

3

0

High-throughput

0.347

High

453918

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

453835

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low

453889

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

453915

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

453939

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024