Protein: GEMI6
Gem-associated protein 6 (Gemin-6) (SIP2)

Gene: GEMI6, GEMIN6
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q8WXD5

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1263369

GEMI7
Gem-associated protein 7

11

1

Small-scale

0.984

High

1263370

GEMI8
Gem-associated protein 8

3

0

High-throughput

0.816

High

911914

RUXF
Small nuclear ribonucleoprotein F

5

3

Small-scale

0.720

High

1084849

SMN
Survival motor neuron protein

7

0

Small-scale

0.718

High

1263377

STRAP
Serine-threonine kinase receptor-associated protein

6

0

Small-scale

0.703

High

157756

GEMI2
Gem-associated protein 2

5

0

Small-scale

0.684

High

1263372

DDX20
Probable ATP-dependent RNA helicase DDX20

5

0

Small-scale

0.684

High

539076

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

1

Small-scale

0.670

High

911701

RUXE
Small nuclear ribonucleoprotein E

4

0

Small-scale

0.667

High

442344

RU17
U1 small nuclear ribonucleoprotein 70 kDa

4

0

High-throughput

0.664

High

884045

GEMI4
Gem-associated protein 4

4

0

Small-scale

0.664

High

912083

RUXG
Small nuclear ribonucleoprotein G

3

6

Small-scale

0.660

High

1263371

SPN90
NCK-interacting protein with SH3 domain

3

0

High-throughput

0.646

High

912525

SMD2
Small nuclear ribonucleoprotein Sm D2

3

0

Small-scale

0.632

High

726956

FUS
RNA-binding protein FUS

2

0

High-throughput

0.585

High

1256649

GEMI5
Gem-associated protein 5

2

0

Small-scale

0.585

High

1263355

ACO11
Acyl-coenzyme A thioesterase 11

2

0

High-throughput

0.580

High

1263358

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

1263366

P2Y12
P2Y purinoceptor 12

2

1

High-throughput

0.558

High

854196

JAK3
Tyrosine-protein kinase JAK3

1

1

High-throughput

0.536

High

927991

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

1

High-throughput

0.536

High

1263363

TBD2A
TBC1 domain family member 2A

1

1

High-throughput

0.536

High

1263374

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

5

High-throughput

0.536

High

912341

SMD1
Small nuclear ribonucleoprotein Sm D1

1

4

Small-scale

0.527

High

351581

NEU2
Vasopressin-neurophysin 2-copeptin

1

0

High-throughput

0.513

High

446721

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448756

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

506630

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.513

High

946374

GPSM2
G-protein-signaling modulator 2

1

0

High-throughput

0.513

High

1110412

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.513

High

1217329

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.513

High

1232260

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1263357

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.513

High

1263360

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1263362

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.513

High

1263378

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.513

High

1263373

NUFP1
FMR1-interacting protein NUFIP1

1

0

Small-scale

0.504

High

912688

SMD3
Small nuclear ribonucleoprotein Sm D3

1

4

Small-scale

0.501

High

1067557

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

167708

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

5

High-throughput

0.479

High

1263376

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

4

High-throughput

0.479

High

1263379

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

4

High-throughput

0.479

High

122905

MEN1
Menin

1

0

High-throughput

0.458

High

338761

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

488763

ARAF
Serine/threonine-protein kinase A-Raf

1

0

High-throughput

0.458

High

714984

PROF2
Profilin-2

1

0

High-throughput

0.458

High

908888

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1042157

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1263356

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1263359

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1263367

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1263368

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1263375

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

68441

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

6

High-throughput

0.445

High

876167

PAR2
Proteinase-activated receptor 2

1

1

High-throughput

0.437

High

1263364

RAB17
Ras-related protein Rab-17

2

0

High-throughput

0.318

High

1263361

RSLBB
Ras-like protein family member 11B

2

0

High-throughput

0.316

High

297533

TOX4
TOX high mobility group box family member 4

1

0

High-throughput

0.299

High

532178

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.279

Low

639618

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.279

Low

1102564

TMM44
Transmembrane protein 44

1

0

High-throughput

0.279

Low

1202516

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1237303

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.279

Low

1263365

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1263380

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

118381

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024