HitPredict

Interactor 1: TM1L2 (Q6ZVM7)
TOM1-like protein 2 (Target of Myb-like protein 2)
Gene: TOM1L2

Interactor 2: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	32296183, 32311122, 35271311, 20936779, 33961781, 16412388, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0043130 - ubiquitin binding GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 274
+	Hs
		241171 TOM1_HUMAN (1-507): 1.07e-155: 454: 61.40		Q6FIE9_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		241195 TOM1_HUMAN (1-507): 1.07e-155: 454: 61.40		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Mm
		292211 TOM1_MOUSE (1-507): 1.21e-159: 464: 60.86		TOLIP_MOUSE (1-273): 2.66e-165: 460: 93.04
+	Rn
		58593 Q5XI21_RAT (1-507): 3.72e-159: 462: 60.27		TOLIP_RAT (1-273): 9.9e-166: 461: 93.41
+	Hs
		1327603 GGA2_HUMAN (5-477): 1.27e-101: 319: 21.15		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		272820 TM1L1_HUMAN (7-468): 4.22e-95: 298: 29.90		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1327604 GGA1_HUMAN (13-474): 5.55e-93: 297: 22.74		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1270615 STAM1_HUMAN (1-491): 2.46e-92: 293: 19.80		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1327594 GGA3_HUMAN (12-497): 1.56e-90: 293: 20.36		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		160182 HGS_HUMAN (13-166): 1.32e-41: 160: 33.55		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00