Protein: EPHA8
Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)

Gene: EPHA8
Organism: Homo sapiens
Interactions: 153
UniProt ID: P29322

Gene Ontology (top 5):
GO:0005003 - ephrin receptor activity
GO:0005004 - GPI-linked ephrin receptor activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

665459

EFNA5
Ephrin-A5

3

20

High-throughput

0.861

High

665481

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

16

High-throughput

0.778

High

412037

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.724

High

616944

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

20

Small-scale

0.692

High

591452

RAB3A
Ras-related protein Rab-3A

1

5

High-throughput

0.691

High

665458

EFNA4
Ephrin-A4

1

20

High-throughput

0.691

High

665462

LAMB2
Laminin subunit beta-2

1

10

High-throughput

0.691

High

665469

BTK
Tyrosine-protein kinase BTK

1

20

High-throughput

0.691

High

665477

EPHA7
Ephrin type-A receptor 7

1

19

High-throughput

0.691

High

665456

RAB7A
Ras-related protein Rab-7a

1

10

High-throughput

0.646

High

665466

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.646

High

501727

BIP
Endoplasmic reticulum chaperone BiP

2

9

High-throughput

0.628

High

528078

BMP1
Bone morphogenetic protein 1

1

3

High-throughput

0.618

High

208997

NCK2
Cytoplasmic protein NCK2

1

20

High-throughput

0.618

High

277012

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.618

High

537718

INSRR
Insulin receptor-related protein

1

19

High-throughput

0.618

High

610245

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.618

High

655221

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

665143

EPHA2
Ephrin type-A receptor 2

1

19

High-throughput

0.618

High

665448

CRKL
Crk-like protein

1

20

High-throughput

0.618

High

665467

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

665474

STIM1
Stromal interaction molecule 1

1

6

High-throughput

0.618

High

665490

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

16

Small-scale

0.618

High

665494

VRK2
Serine/threonine-protein kinase VRK2

1

13

High-throughput

0.618

High

665499

UNC5B
Netrin receptor UNC5B

1

13

High-throughput

0.618

High

665506

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

20

Small-scale

0.618

High

665508

STAM1
Signal transducing adapter molecule 1

1

20

High-throughput

0.618

High

665522

OSBL8
Oxysterol-binding protein-related protein 8

1

5

High-throughput

0.618

High

665533

WDR6
tRNA

1

15

High-throughput

0.618

High

665543

TBK1
Serine/threonine-protein kinase TBK1

1

12

High-throughput

0.618

High

665510

LRC59
Leucine-rich repeat-containing protein 59

1

20

High-throughput

0.578

High

665476

NUCG
Endonuclease G, mitochondrial

2

2

High-throughput

0.574

High

118695

AIP
AH receptor-interacting protein

1

9

High-throughput

0.553

High

129210

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.553

High

573583

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.553

High

665444

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.553

High

665461

COPA
Coatomer subunit alpha

1

5

High-throughput

0.553

High

665463

SEC13
Protein SEC13 homolog

1

3

High-throughput

0.553

High

665495

LRC49
Leucine-rich repeat-containing protein 49

1

20

High-throughput

0.553

High

665502

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.553

High

665528

WDR41
WD repeat-containing protein 41

1

4

High-throughput

0.553

High

665535

AAAS
Aladin

1

7

High-throughput

0.553

High

665550

S23IP
SEC23-interacting protein

1

6

High-throughput

0.553

High

665473

G3BP1
Ras GTPase-activating protein-binding protein 1

1

5

High-throughput

0.541

High

665487

SYDM
Aspartate--tRNA ligase, mitochondrial

1

5

High-throughput

0.541

High

665546

HYOU1
Hypoxia up-regulated protein 1

1

19

High-throughput

0.536

High

646370

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.518

High

665465

PRS8
26S proteasome regulatory subunit 8

1

0

High-throughput

0.518

High

571675

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

7

High-throughput

0.500

High

665442

PEBP1
Phosphatidylethanolamine-binding protein 1

1

4

High-throughput

0.500

High

665468

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

7

High-throughput

0.500

High

665471

LG3BP
Galectin-3-binding protein

1

4

High-throughput

0.500

High

665489

MON2
Protein MON2 homolog

1

4

High-throughput

0.500

High

665518

NTPCR
Cancer-related nucleoside-triphosphatase

1

8

High-throughput

0.500

High

313616

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

5

High-throughput

0.489

High

531731

PDIA4
Protein disulfide-isomerase A4

1

20

High-throughput

0.489

High

654091

CALX
Calnexin

1

10

High-throughput

0.489

High

665455

EMD
Emerin

1

7

High-throughput

0.489

High

665480

CDC37
Hsp90 co-chaperone Cdc37

1

19

High-throughput

0.489

High

665498

TRM2A
tRNA

1

2

High-throughput

0.489

High

665454

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.479

High

159899

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.479

High

180818

YKT6
Synaptobrevin homolog YKT6

1

4

High-throughput

0.479

High

310518

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

9

High-throughput

0.479

High

320817

HS74L
Heat shock 70 kDa protein 4L

1

11

High-throughput

0.479

High

574601

ARF4
ADP-ribosylation factor 4

1

14

High-throughput

0.479

High

665443

CTNB1
Catenin beta-1

1

16

High-throughput

0.479

High

665445

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

3

High-throughput

0.479

High

665449

NSF
Vesicle-fusing ATPase

1

1

High-throughput

0.479

High

665451

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

13

Small-scale

0.479

High

665460

COPB
Coatomer subunit beta

1

3

High-throughput

0.479

High

665470

CKAP4
Cytoskeleton-associated protein 4

1

16

High-throughput

0.479

High

665492

LYRIC
Protein LYRIC

1

2

High-throughput

0.479

High

665500

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

6

High-throughput

0.479

High

665504

SCFD1
Sec1 family domain-containing protein 1

1

2

High-throughput

0.479

High

665505

HS105
Heat shock protein 105 kDa

1

19

High-throughput

0.479

High

665509

SYAP1
Synapse-associated protein 1

1

1

High-throughput

0.479

High

665513

ASTRA
Protein Aster-A

1

4

High-throughput

0.479

High

665520

NDC1
Nucleoporin NDC1

1

1

High-throughput

0.479

High

665524

OSBL2
Oxysterol-binding protein-related protein 2

1

5

High-throughput

0.479

High

665530

VEZA
Vezatin

1

1

High-throughput

0.479

High

665531

JPH1
Junctophilin-1

1

10

High-throughput

0.479

High

665538

VAPA
Vesicle-associated membrane protein-associated protein A

1

9

High-throughput

0.479

High

665544

NISCH
Nischarin

1

20

High-throughput

0.479

High

665486

ZN746
Zinc finger protein 746

1

7

High-throughput

0.464

High

665516

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

665525

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.458

High

665547

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

High-throughput

0.458

High

130445

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

6

High-throughput

0.457

High

268407

BAF
Barrier-to-autointegration factor

1

6

High-throughput

0.457

High

456505

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

4

High-throughput

0.457

High

536313

GLU2B
Glucosidase 2 subunit beta

1

2

High-throughput

0.457

High

665446

HUTH
Histidine ammonia-lyase

1

1

High-throughput

0.457

High

665464

COPZ1
Coatomer subunit zeta-1

1

3

High-throughput

0.457

High

665491

YTHD3
YTH domain-containing family protein 3

1

8

High-throughput

0.457

High

665521

YTHD1
YTH domain-containing family protein 1

1

8

High-throughput

0.457

High

665529

XPO5
Exportin-5

1

5

High-throughput

0.457

High

665541

DJB11
DnaJ homolog subfamily B member 11

1

13

High-throughput

0.457

High

665475

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

68540

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

3

High-throughput

0.437

High

132422

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

149553

COPE
Coatomer subunit epsilon

1

3

High-throughput

0.437

High

164794

SC16A
Protein transport protein Sec16A

1

5

High-throughput

0.437

High

170802

PGRC2
Membrane-associated progesterone receptor component 2

1

4

High-throughput

0.437

High

240697

USO1
General vesicular transport factor p115

1

8

High-throughput

0.437

High

242813

TRI13
E3 ubiquitin-protein ligase TRIM13

1

12

High-throughput

0.437

High

264009

TACC1
Transforming acidic coiled-coil-containing protein 1

1

14

High-throughput

0.437

High

273698

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.437

High

302258

SC31A
Protein transport protein Sec31A

1

5

High-throughput

0.437

High

315523

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.437

High

315657

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.437

High

390724

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.437

High

438699

SRPRA
Signal recognition particle receptor subunit alpha

1

5

High-throughput

0.437

High

665447

MTHR
Methylenetetrahydrofolate reductase

1

1

High-throughput

0.437

High

665450

COPD
Coatomer subunit delta

1

4

High-throughput

0.437

High

665452

LMAN1
Protein ERGIC-53

1

4

High-throughput

0.437

High

665453

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

4

High-throughput

0.437

High

665457

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

4

High-throughput

0.437

High

665472

STX5
Syntaxin-5

1

4

High-throughput

0.437

High

665478

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.437

High

665479

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.437

High

665482

RABL3
Rab-like protein 3

1

20

High-throughput

0.437

High

665483

TGO1
Transport and Golgi organization protein 1 homolog

1

9

High-throughput

0.437

High

665484

TOIP1
Torsin-1A-interacting protein 1

1

3

High-throughput

0.437

High

665485

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.437

High

665493

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

2

High-throughput

0.437

High

665496

NUDC3
NudC domain-containing protein 3

1

4

High-throughput

0.437

High

665501

EMC1
ER membrane protein complex subunit 1

1

5

High-throughput

0.437

High

665507

TFG
Protein TFG

1

4

High-throughput

0.437

High

665514

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

665515

CK5P3
CDK5 regulatory subunit-associated protein 3

1

2

High-throughput

0.437

High

665517

CLCC1
Chloride channel CLIC-like protein 1

1

4

High-throughput

0.437

High

665519

ESYT1
Extended synaptotagmin-1

1

9

High-throughput

0.437

High

665523

LSG1
Large subunit GTPase 1 homolog

1

3

High-throughput

0.437

High

665526

GCP60
Golgi resident protein GCP60

1

8

High-throughput

0.437

High

665527

GORS2
Golgi reassembly-stacking protein 2

1

9

High-throughput

0.437

High

665534

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

10

High-throughput

0.437

High

665537

HACD3
Very-long-chain

1

3

High-throughput

0.437

High

665539

F135A
Protein FAM135A

1

5

High-throughput

0.437

High

665540

COPG2
Coatomer subunit gamma-2

1

6

High-throughput

0.437

High

665542

TRM7
tRNA

1

7

High-throughput

0.437

High

665545

MAN1
Inner nuclear membrane protein Man1

1

3

High-throughput

0.437

High

665548

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.437

High

665549

COPG1
Coatomer subunit gamma-1

1

6

High-throughput

0.437

High

588405

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

665488

ABH15
Protein ABHD15

1

0

High-throughput

0.279

Low

665497

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

457132

ALDOC
Fructose-bisphosphate aldolase C

1

0

High-throughput

0.261

Low

665503

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.249

Low

665511

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.249

Low

665512

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

665532

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.249

Low

665536

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024