Protein: SIMA
Protein similar

Gene: SIMA
Organism: Drosophila melanogaster
Interactions: 204
UniProt ID: Q24167

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

194888

ARNT
Aryl hydrocarbon receptor nuclear translocator homolog

3

20

Small-scale

0.865

High

1172625

Q8WS79
Estrogen-related receptor splice variant

2

20

Small-scale

0.619

High

1172651

Q9VAY2
Heat shock protein 83

1

17

High-throughput

0.553

High

1172612

Q86CW5
Hmr

1

0

High-throughput

0.518

High

892165

HNF4
Transcription factor HNF-4 homolog

1

20

High-throughput

0.508

High

1172649

Q9VAV6
Histone acetyltransferase

1

3

High-throughput

0.508

High

55630

A1Z9I5
Rac GTPase-activating protein 1

1

5

High-throughput

0.479

High

68234

A8DYB0
Midasin

1

12

High-throughput

0.479

High

69293

A8JV07
Uncharacterized protein, isoform B

1

5

High-throughput

0.479

High

84945

B7Z0X1
Serine hydroxymethyltransferase

1

1

High-throughput

0.479

High

118622

M9NF14
IGF-II mRNA-binding protein, isoform L

1

2

High-throughput

0.479

High

120878

M9PEE1
Smallminded, isoform H

1

8

High-throughput

0.479

High

120966

M9PEH8
Fiery mountain, isoform D

1

2

High-throughput

0.479

High

198142

GBLP
Small ribosomal subunit protein RACK1

1

9

High-throughput

0.479

High

263476

O61380
Eukaryotic translation initiation factor 4G1, isoform A

1

2

High-throughput

0.479

High

264594

KPYK
Pyruvate kinase

1

3

High-throughput

0.479

High

554083

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.479

High

559797

EF2
Eukaryotic translation elongation factor 2

1

2

High-throughput

0.479

High

633061

NCD
Protein claret segregational

1

2

High-throughput

0.479

High

674016

BRM
ATP-dependent helicase brm

1

9

High-throughput

0.479

High

709530

1433Z
14-3-3 protein zeta

1

3

High-throughput

0.479

High

715351

BIP
Endoplasmic reticulum chaperone BiP

1

9

High-throughput

0.479

High

760393

TTF2
Transcription termination factor 2

1

3

High-throughput

0.479

High

773362

RFC1
Replication factor C subunit 1

1

6

High-throughput

0.479

High

823758

SQH
Myosin regulatory light chain sqh

1

2

High-throughput

0.479

High

838645

LOLA2
Longitudinals lacking protein, isoforms H/M/V

1

4

High-throughput

0.479

High

874966

PRS4
26S proteasome regulatory subunit 4

1

9

High-throughput

0.479

High

916490

RFC2
Replication factor C subunit 2

1

5

High-throughput

0.479

High

1038225

IF4A
Eukaryotic initiation factor 4A

1

1

High-throughput

0.479

High

1052808

T2FA
General transcription factor IIF subunit 1

1

4

High-throughput

0.479

High

1059138

ROP
Protein ROP

1

2

High-throughput

0.479

High

1069808

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

2

High-throughput

0.479

High

1171737

FLII
Protein flightless-1

1

2

High-throughput

0.479

High

1172592

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

10

High-throughput

0.479

High

1172593

CAF1
Chromatin assembly factor 1 p55 subunit

1

5

High-throughput

0.479

High

1172594

DX39B
ATP-dependent RNA helicase WM6

1

2

High-throughput

0.479

High

1172600

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.479

High

1172601

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

1172602

Q7K3D4
peptidylprolyl isomerase

1

10

High-throughput

0.479

High

1172604

Q7K4G8
LD40944p

1

3

High-throughput

0.479

High

1172607

Q7KMQ0
26S proteasome regulatory subunit 7

1

8

High-throughput

0.479

High

1172608

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

4

High-throughput

0.479

High

1172624

Q8T8W3
AT21416p

1

1

High-throughput

0.479

High

1172627

LDH
L-lactate dehydrogenase

1

1

High-throughput

0.479

High

1172629

Q95RE4
LD37574p

1

1

High-throughput

0.479

High

1172631

MYSN
Myosin heavy chain, non-muscle

1

8

High-throughput

0.479

High

1172632

Q9N6D8
GH11591p

1

7

High-throughput

0.479

High

1172633

MLF
Myeloid leukemia factor

1

4

High-throughput

0.479

High

1172637

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.479

High

1172639

Q9V3V6
26S proteasome regulatory complex subunit p50

1

12

High-throughput

0.479

High

1172640

Q9V405
26S proteasome regulatory subunit 6B

1

6

High-throughput

0.479

High

1172642

Q9V455
Importin subunit alpha

1

13

High-throughput

0.479

High

1172658

Q9VF03
Brahma associated protein 155 kDa

1

10

High-throughput

0.479

High

1172662

Q9VFV9
DnaJ-like-2, isoform A

1

10

High-throughput

0.479

High

1172663

IPO9
Importin-9

1

7

High-throughput

0.479

High

1172664

Q9VHC7
FI21236p1

1

1

High-throughput

0.479

High

1172665

Q9VHL2
T-complex protein 1 subunit eta

1

2

High-throughput

0.479

High

1172668

Q9VJ86
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

1172671

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

8

High-throughput

0.479

High

1172674

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

6

High-throughput

0.479

High

1172677

Q9VP57
LD15904p

1

1

High-throughput

0.479

High

1172679

DJSHV
DnaJ homolog shv

1

11

High-throughput

0.479

High

1172684

Q9VRL8
Blanks

1

3

High-throughput

0.479

High

1172692

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

1

High-throughput

0.479

High

1172694

Q9VV52
LD37257p

1

16

High-throughput

0.479

High

1172700

HANG
Zinc finger protein hangover

1

1

High-throughput

0.479

High

1172705

FBXW7
F-box/WD repeat-containing protein 7

1

7

Small-scale

0.479

High

1172706

Q9VZF5
Kinesin-like protein

1

3

High-throughput

0.479

High

1172709

Q9W0L7
ubiquitinyl hydrolase 1

1

10

High-throughput

0.479

High

1172711

Q9W0R0
Cell division cycle 5, isoform A

1

1

High-throughput

0.479

High

1172712

Q9W1G7
LD21576p

1

2

High-throughput

0.479

High

1172715

RTF1
RNA polymerase-associated protein Rtf1

1

2

High-throughput

0.479

High

1172719

Q9W384
Brahma associated protein 111kD

1

7

High-throughput

0.479

High

1172722

Q9W414
Regulatory particle triple-A ATPase 4

1

8

High-throughput

0.479

High

95209

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.458

High

357121

O97365
BM-40

1

0

High-throughput

0.458

High

561779

MODU
DNA-binding protein modulo

1

0

High-throughput

0.458

High

1172144

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.458

High

1172597

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.458

High

1172598

Q7JXC4
CG6459 protein

1

0

High-throughput

0.458

High

1172615

Q8IR93
Dynein light intermediate chain

1

0

High-throughput

0.458

High

1172617

INDRA
Zinc finger protein indra

1

0

High-throughput

0.458

High

1172622

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.458

High

1172623

PUF68
Poly(U)-binding-splicing factor hfp

1

0

High-throughput

0.458

High

1172626

Q94883
DNA replication-related element factor, isoform A

1

0

High-throughput

0.458

High

1172634

CWC15
Protein CWC15 homolog

1

0

High-throughput

0.458

High

1172635

VHL
Protein Vhl

1

0

Small-scale

0.458

High

1172636

Q9V3E7
LD24793p

1

0

High-throughput

0.458

High

1172646

Q9V9Q4
LD43819p

1

0

High-throughput

0.458

High

1172648

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

1172654

Q9VBX3
Vig2, isoform B

1

0

High-throughput

0.458

High

1172655

Q9VC05
Oxysterol-binding protein

1

0

High-throughput

0.458

High

1172660

GYS
Glycogen [starch] synthase

1

0

High-throughput

0.458

High

1172666

Q9VHN7
transketolase

1

0

High-throughput

0.458

High

1172669

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.458

High

1172670

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.458

High

1172685

Q9VRP3
AT08565p

1

0

High-throughput

0.458

High

1172689

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1172690

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.458

High

1172699

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.458

High

1172701

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.458

High

1172710

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.458

High

1172716

DCAF1
Protein mahjong

1

0

High-throughput

0.458

High

1172726

NSUN2
tRNA

1

0

High-throughput

0.458

High

1172628

Q95R37
SD10969p

1

1

High-throughput

0.457

High

1172691

Q9VSE9
Estrogen-related receptor

1

20

High-throughput

0.457

High

1172686

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

8

High-throughput

0.445

High

1172656

RLIP
RalA-binding protein 1

1

4

High-throughput

0.439

High

145779

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

6

High-throughput

0.437

High

263371

PENG
Protein penguin

1

1

High-throughput

0.437

High

263554

O61444
mitogen-activated protein kinase kinase

1

18

High-throughput

0.437

High

264525

O62602
mitogen-activated protein kinase kinase

1

13

High-throughput

0.437

High

264633

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.437

High

304435

PKHF1
Pleckstrin homology domain-containing family F member 1 homolog

1

1

High-throughput

0.437

High

476470

TBB3
Tubulin beta-3 chain

1

4

High-throughput

0.437

High

561573

SPTCA
Spectrin alpha chain

1

3

High-throughput

0.437

High

654846

MA205
205 kDa microtubule-associated protein

1

3

High-throughput

0.437

High

704347

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.437

High

770941

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

1052388

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.437

High

1069728

Q0E931
GTP-binding protein 1

1

1

High-throughput

0.437

High

1172591

RS5A
Small ribosomal subunit protein uS7A

1

1

High-throughput

0.437

High

1172595

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

2

High-throughput

0.437

High

1172605

Q7KHK9
DREAM

1

3

High-throughput

0.437

High

1172606

Q7KLW9
Pre-mRNA-processing factor 19

1

7

High-throughput

0.437

High

1172611

Q7KV70
Karst, isoform C

1

3

High-throughput

0.437

High

1172614

Q8IQQ0
2-oxoglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.437

High

1172619

Q8MST5
Tubulin beta chain

1

4

High-throughput

0.437

High

1172630

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.437

High

1172638

Q9V3U6
26-29kD-proteinase

1

1

High-throughput

0.437

High

1172641

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.437

High

1172643

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.437

High

1172645

EPB41
Protein 4.1 homolog

1

2

High-throughput

0.437

High

1172652

Q9VBN5
60S ribosomal protein L27

1

1

High-throughput

0.437

High

1172657

Q9VEN3
non-specific serine/threonine protein kinase

1

4

High-throughput

0.437

High

1172672

Q9VLK1
U3 small nucleolar ribonucleoprotein protein MPP10

1

2

High-throughput

0.437

High

1172673

POE
Protein purity of essence

1

1

High-throughput

0.437

High

1172675

CATF
Cathepsin F

1

1

High-throughput

0.437

High

1172681

Q9VQK7
LD45152p

1

1

High-throughput

0.437

High

1172682

Q9VQL7
Fatty acid synthase

1

1

High-throughput

0.437

High

1172687

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.437

High

1172688

Q9VS57
RE14391p

1

4

High-throughput

0.437

High

1172698

Q9VVG9
Uncharacterized protein

1

3

High-throughput

0.437

High

1172703

Q9VXR5
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.437

High

1172708

Q9W0B8
Coatomer subunit alpha

1

8

High-throughput

0.437

High

1172720

Q9W392
T-complex protein 1 subunit beta

1

3

High-throughput

0.437

High

1172724

Q9W425
Rabconnectin-3A

1

6

High-throughput

0.437

High

1172728

X2JE07
Uncharacterized protein, isoform D

1

2

High-throughput

0.437

High

1172697

Q9VVC2
Uncharacterized protein

1

0

High-throughput

0.265

Low

56731

A1ZAH8
40S ribosomal protein S15

1

0

High-throughput

0.249

Low

57160

PTRO
Patronin

1

0

High-throughput

0.249

Low

95099

E1JHG4
Uncharacterized protein, isoform C

1

0

High-throughput

0.249

Low

196068

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

262622

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

429090

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low

471477

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.249

Low

607483

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.249

Low

652017

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

0

High-throughput

0.249

Low

710934

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.249

Low

715091

CLH
Clathrin heavy chain

1

0

High-throughput

0.249

Low

832163

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

832182

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.249

Low

832255

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.249

Low

856459

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.249

Low

870535

RS15A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

870598

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.249

Low

898283

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.249

Low

938992

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.249

Low

1070022

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.249

Low

1172596

Q7JQH9
carnitine O-palmitoyltransferase

1

0

High-throughput

0.249

Low

1172599

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

1

0

High-throughput

0.249

Low

1172603

Q7K485
Cathepsin D

1

0

High-throughput

0.249

Low

1172609

Q7KN94
Electron transfer flavoprotein subunit alpha

1

0

High-throughput

0.249

Low

1172610

Q7KS14
Uncharacterized protein, isoform B

1

0

High-throughput

0.249

Low

1172613

Q8I937
Ribosome biogenesis regulatory protein

1

0

High-throughput

0.249

Low

1172616

Q8IRH0
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.249

Low

1172618

Q8IRJ7
Dis3 like 3'-5' exoribonuclease 2, isoform C

1

0

High-throughput

0.249

Low

1172620

Q8SX89
Kugelkern, isoform A

1

0

High-throughput

0.249

Low

1172621

CHM4
Charged multivesicular body protein 4

1

0

High-throughput

0.249

Low

1172644

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

1172647

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1172650

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.249

Low

1172653

Q9VBU9
40S ribosomal protein S27

1

0

High-throughput

0.249

Low

1172659

Q9VF05
RE18415p

1

0

High-throughput

0.249

Low

1172661

RRP15
RRP15-like protein

1

0

High-throughput

0.249

Low

1172667

Q9VJ19
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

1172676

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.249

Low

1172680

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.249

Low

1172693

Q9VUZ0
Translocon-associated protein subunit beta

1

0

High-throughput

0.249

Low

1172695

Q9VV75
AT02348p

1

0

High-throughput

0.249

Low

1172696

Q9VV79
BcDNA.LD24702

1

0

High-throughput

0.249

Low

1172702

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.249

Low

1172704

BRX1
Ribosome biogenesis protein BRX1 homolog

1

0

High-throughput

0.249

Low

1172707

Q9W0A8
FI01658p

1

0

High-throughput

0.249

Low

1172713

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

1172714

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.249

Low

1172717

CAPZA
F-actin-capping protein subunit alpha

1

0

High-throughput

0.249

Low

1172718

Q9W335
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

1172721

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.249

Low

1172723

Q9W424
Splicing factor 3B subunit 4

1

0

High-throughput

0.249

Low

1172725

Q9W4C1
IP13321p

1

0

High-throughput

0.249

Low

1172727

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.249

Low

1172678

Q9VPH3
Uncharacterized protein, isoform B

1

0

High-throughput

0.238

Low

1172683

Q9VRB7
GH11587p

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025