Protein: PP12
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)

Gene: PP12, Pp1-87B
Organism: Drosophila melanogaster
Interactions: 90
UniProt ID: P12982

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0000278 - mitotic cell cycle
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005700 - polytene chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

524606

PP1B
Serine/threonine-protein phosphatase beta isoform

4

13

High-throughput

0.861

High

65574

A8JNP7
Inhibitor-2, isoform B

3

20

High-throughput

0.741

High

524633

Q8T0U6
Serine/threonine-protein phosphatase

2

13

High-throughput

0.712

High

524639

Q9V3C7
Inhibitor-2

3

20

High-throughput

0.701

High

524615

Q4V424
IP09433p

2

20

High-throughput

0.693

High

524641

Q9V7W9
Nuclear inhibitor of protein phosphatase 1

3

9

Small-scale

0.649

High

524604

SQH
Myosin regulatory light chain sqh

1

6

Small-scale

0.647

High

524612

KTU
Protein kintoun

2

9

High-throughput

0.640

High

524622

SCRIB
Protein lap4

1

14

High-throughput

0.625

High

524623

Q7KU01
Phosphatase 1 nuclear targeting subunit, isoform D

2

20

Small-scale

0.619

High

524652

Q9VIP4
LP17758p

2

14

Small-scale

0.609

High

524647

Q9VEK8
GH07711p

2

20

Small-scale

0.584

High

524656

Q9VMW2
Reticulon-like protein

2

2

High-throughput

0.584

High

524673

RIF1
Telomere-associated protein RIF1

2

3

Small-scale

0.584

High

112914

M9NF08
ZAP3, isoform D

2

7

High-throughput

0.584

High

524621

Q7K9H6
Zinc finger FYVE domain-containing protein

2

17

Small-scale

0.584

High

524629

Q8SWT8
Protein phosphatase 1 regulatory subunit

2

20

Small-scale

0.584

High

524671

Q9W2Y5
ZAP3, isoform C

2

13

High-throughput

0.565

High

524601

TRX
Histone-lysine N-methyltransferase trithorax

2

5

High-throughput

0.560

High

524636

Q95TZ7
GH19182p

1

13

High-throughput

0.555

High

524609

FKB39
39 kDa FK506-binding nuclear protein

1

3

Small-scale

0.553

High

524668

URI
Unconventional prefoldin RPB5 interactor-like protein

1

3

Small-scale

0.552

High

524655

Q9VMV9
Reticulon-like protein

2

2

High-throughput

0.552

High

524653

Q9VK43
LD10135p

2

3

High-throughput

0.550

High

524657

Q9VQS4
Spindly

2

3

High-throughput

0.550

High

524676

X2JKX2
Corolla, isoform B

2

7

High-throughput

0.533

High

524664

Q9VX37
Corolla, isoform A

2

7

High-throughput

0.516

High

55510

A1ZAW3
FI17823p1

1

5

High-throughput

0.508

High

246691

LOK
Ovarian-specific serine/threonine-protein kinase Lok

1

6

High-throughput

0.508

High

524602

CDK2
Cyclin-dependent kinase 2

1

13

High-throughput

0.508

High

524608

DOA
Serine/threonine-protein kinase Doa

1

13

High-throughput

0.508

High

524619

Q7K306
Cyclin-dependent kinase 4, isoform A

1

14

High-throughput

0.508

High

524620

MARS
Guanylate kinase-associated protein mars

1

5

High-throughput

0.508

High

524624

Q86B80
Uncharacterized protein, isoform A

1

3

High-throughput

0.508

High

524632

Q8T0D1
LD10183p

1

3

High-throughput

0.508

High

524644

Q9VDX4
MIP05121p

1

3

High-throughput

0.508

High

524658

Q9VRC5
E3 ubiquitin-protein ligase PPP1R11

1

10

High-throughput

0.508

High

524662

GBS76
Glycogen-binding subunit 76A

1

20

High-throughput

0.508

High

524663

Q9VWB7
LD06925p

1

6

High-throughput

0.508

High

524669

Q9W1E4
GH11727p

1

3

High-throughput

0.508

High

115662

M9PFV2
Myosin phosphatase targeting subunit 75D, isoform B

1

20

Small-scale

0.501

High

115976

M9PH39
histone acetyltransferase

1

13

High-throughput

0.481

High

524638

SIRT2
NAD-dependent protein deacetylase Sirt2

1

5

High-throughput

0.481

High

524675

X2J8G3
Mrityu, isoform E

1

10

High-throughput

0.481

High

65655

A8JQV1
Uncharacterized protein, isoform C

1

3

High-throughput

0.479

High

429411

PER
Period circadian protein

1

7

Small-scale

0.479

High

524603

PC
Polycomb group protein Pc

1

2

Small-scale

0.479

High

524605

MOEH
Moesin/ezrin/radixin homolog 1

1

10

Small-scale

0.479

High

524607

TIM
Protein timeless

1

3

Small-scale

0.479

High

524610

SMO
Protein smoothened

1

12

Small-scale

0.479

High

524634

Q94533
Ribosomal protein S6 kinase

1

10

High-throughput

0.479

High

524643

CRERF
Protein CREBRF homolog

1

1

Small-scale

0.479

High

524645

Q9VEH1
LD04521p

1

20

Small-scale

0.479

High

524646

SUR8
Leucine-rich repeat protein soc-2 homolog

1

16

Small-scale

0.479

High

524654

Q9VMI2
E3 ubiquitin-protein ligase PPP1R11

1

19

High-throughput

0.479

High

524660

Q9VUX7
GH16214p

1

17

Small-scale

0.479

High

524670

Q9W2J2
Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform A

1

20

Small-scale

0.479

High

524628

Q8MRN4
GH12664p

1

3

High-throughput

0.464

High

524640

Q9V4B8
RE68558p

1

6

High-throughput

0.464

High

524648

Q9VF13
Uncharacterized protein, isoform C

1

20

High-throughput

0.464

High

524650

Q9VGJ2
Inhibitor-t

1

1

High-throughput

0.464

High

524665

Q9VXK9
RH04127p

1

1

High-throughput

0.464

High

524611

Q0E8K5
AT10158p

1

10

High-throughput

0.457

High

524617

Q70HU3
PNUTSDm protein

1

20

High-throughput

0.457

High

524618

Q7JMZ1
Kinesin-like protein

1

14

High-throughput

0.457

High

524625

Q8IH02
LD38891p

1

7

High-throughput

0.457

High

524630

Q8SXG7
tRNA selenocysteine-associated protein 1

1

9

High-throughput

0.457

High

524631

Q8SYZ4
NAD-dependent protein deacetylase

1

5

High-throughput

0.457

High

524635

Q95TP4
LD33277p

1

1

High-throughput

0.457

High

524637

Q960V6
Zinc finger FYVE domain-containing protein

1

15

High-throughput

0.457

High

524659

Q9VUF3
Protein phosphatase 1 regulatory subunit

1

20

High-throughput

0.457

High

524616

Q4V467
IP10845p

1

3

High-throughput

0.445

High

524667

Q9W0L7
ubiquitinyl hydrolase 1

1

4

High-throughput

0.445

High

66189

A8JUY3
DNA-directed RNA polymerase subunit

1

8

High-throughput

0.439

High

116081

M9PHL2
Heterochromatin protein 5, isoform C

1

1

High-throughput

0.439

High

524613

Q1W9Q0
Echinus splice form 1

1

7

High-throughput

0.439

High

524672

Q9W4P6
FI03654p

1

1

High-throughput

0.439

High

524674

R9PY70
Uncharacterized protein, isoform G

1

7

High-throughput

0.439

High

284829

O77283
Echinus

1

7

High-throughput

0.417

High

524626

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

8

High-throughput

0.417

High

524627

Q8IRT1
Uncharacterized protein, isoform D

1

1

High-throughput

0.417

High

524642

Q9V9N7
GH01875p

1

7

High-throughput

0.417

High

524666

Q9VYY7
Heterochromatin protein 5, isoform B

1

1

High-throughput

0.417

High

184265

O16866
Kinesin-like protein, KLP38B

1

14

High-throughput

0.381

High

183631

O16125
Bifocal

1

0

High-throughput

0.365

High

332248

O96723
Inhibitor-t protein

1

1

High-throughput

0.348

High

524614

Q4QPV3
IP04645p

1

0

High-throughput

0.265

Low

524649

Q9VGI1
FI23955p1

1

0

High-throughput

0.265

Low

524651

Q9VIB1
Carboxylic ester hydrolase

1

0

High-throughput

0.265

Low

524661

Q9VVQ1
Allatostatin C receptor 1

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024