Protein: NHP2
H/ACA ribonucleoprotein complex subunit 2 (Nucleolar protein family A member 2) (snoRNP protein NHP2)

Gene: NHP2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q9NX24

Gene Ontology (top 5):
GO:0000470 - maturation of LSU-rRNA
GO:0000781 - chromosome, telomeric region
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005697 - telomerase holoenzyme complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342705

NOP10
H/ACA ribonucleoprotein complex subunit 3

8

2

High-throughput

0.974

High

242583

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

4

4

Small-scale

0.691

High

1251245

WDR48
WD repeat-containing protein 48

1

10

High-throughput

0.665

High

1347679

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

2

Small-scale

0.624

High

903552

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.618

High

1128549

HABP4
Intracellular hyaluronan-binding protein 4

1

2

High-throughput

0.618

High

1241034

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.618

High

1293737

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

Small-scale

0.611

High

1347676

GAR1
H/ACA ribonucleoprotein complex subunit 1

2

4

High-throughput

0.611

High

1347675

LYAR
Cell growth-regulating nucleolar protein

2

0

High-throughput

0.585

High

348047

MYC
Myc proto-oncogene protein

2

6

High-throughput

0.584

High

370559

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

1334566

LN28A
Protein lin-28 homolog A

2

8

High-throughput

0.571

High

1347686

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.561

High

1146892

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.553

High

739320

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

781843

MNDA
Myeloid cell nuclear differentiation antigen

1

5

High-throughput

0.536

High

931449

YBOX1
Y-box-binding protein 1

1

7

High-throughput

0.536

High

964269

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.536

High

1028850

SRSF5
Serine/arginine-rich splicing factor 5

1

7

High-throughput

0.536

High

1029132

SRSF6
Serine/arginine-rich splicing factor 6

1

9

High-throughput

0.536

High

1202144

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

1344131

DDX21
Nucleolar RNA helicase 2

1

7

High-throughput

0.536

High

253606

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

1

High-throughput

0.526

High

867266

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

1103268

C19L2
CWF19-like protein 2

1

0

High-throughput

0.513

High

1183240

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

1347170

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

1157390

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

2

High-throughput

0.508

High

930419

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

1299650

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

12

High-throughput

0.501

High

1310682

UTP23
rRNA-processing protein UTP23 homolog

1

2

Small-scale

0.501

High

501114

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

1

High-throughput

0.494

High

792029

HD
Huntingtin

1

0

High-throughput

0.493

High

363323

FINC
Fibronectin

1

2

High-throughput

0.489

High

123043

MEN1
Menin

1

2

High-throughput

0.479

High

163368

XPO1
Exportin-1

1

4

High-throughput

0.479

High

233654

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

267081

SRS10
Serine/arginine-rich splicing factor 10

1

3

High-throughput

0.479

High

304369

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

High-throughput

0.479

High

309105

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

331890

NSD2
Histone-lysine N-methyltransferase NSD2

1

4

Small-scale

0.479

High

360478

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

Small-scale

0.479

High

377736

GCR
Glucocorticoid receptor

1

5

High-throughput

0.479

High

379943

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.479

High

403352

LA
Lupus La protein

1

6

High-throughput

0.479

High

591114

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

718246

BMI1
Polycomb complex protein BMI-1

1

7

High-throughput

0.479

High

719190

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

738082

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

801966

RECQ1
ATP-dependent DNA helicase Q1

1

4

High-throughput

0.479

High

818525

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

824452

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

855956

ZN131
Zinc finger protein 131

1

8

High-throughput

0.479

High

918036

H4
Histone H4

1

2

High-throughput

0.479

High

925138

TRA2B
Transformer-2 protein homolog beta

1

5

High-throughput

0.479

High

935303

H31
Histone H3.1

1

1

High-throughput

0.479

High

959715

VIGLN
Vigilin

1

3

High-throughput

0.479

High

960575

PURA
Transcriptional activator protein Pur-alpha

1

1

High-throughput

0.479

High

971380

H11
Histone H1.1

1

3

High-throughput

0.479

High

1016252

FOXO1
Forkhead box protein O1

1

3

High-throughput

0.479

High

1033747

IKZF1
DNA-binding protein Ikaros

1

3

High-throughput

0.479

High

1034138

TCOF
Treacle protein

1

1

Small-scale

0.479

High

1036141

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1061079

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

1

Small-scale

0.479

High

1063647

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1064777

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1085992

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1168966

LN28B
Protein lin-28 homolog B

1

12

High-throughput

0.479

High

1187958

RM21
Large ribosomal subunit protein bL21m

1

1

High-throughput

0.479

High

1201716

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.479

High

1235671

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1256434

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1269759

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1304139

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

1319085

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1335198

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

1347678

RM27
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.479

High

1347681

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1347682

NOL12
Nucleolar protein 12

1

1

High-throughput

0.479

High

1347683

IKZF3
Zinc finger protein Aiolos

1

3

High-throughput

0.479

High

827108

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

981459

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1253423

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

1316577

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.458

High

1328190

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.458

High

1345192

RM17
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.458

High

1347677

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.458

High

1347680

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

808295

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

12

High-throughput

0.457

High

1057687

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

1156073

HMBX1
Homeobox-containing protein 1

1

3

Small-scale

0.445

High

70712

MYO9A
Unconventional myosin-IXa

1

1

High-throughput

0.437

High

149354

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.437

High

374975

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

909218

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1018197

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

3

High-throughput

0.437

High

1286718

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

1288715

RM38
Large ribosomal subunit protein mL38

1

1

High-throughput

0.437

High

1336070

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

2

High-throughput

0.437

High

1347285

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.437

High

1347684

TRAF6
TNF receptor-associated factor 6

1

5

High-throughput

0.437

High

1347685

MAFB
Transcription factor MafB

1

2

High-throughput

0.437

High

1264737

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.282

High

413067

CHLE
Cholinesterase

1

0

High-throughput

0.279

Low

1294814

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.279

Low

101231

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

378189

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

1033245

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

1191994

FBX33
F-box only protein 33

1

0

High-throughput

0.249

Low

1235037

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

1243965

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024