Protein: DKK3
Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (hDkk-3)

Gene: DKK3
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9UBP4

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0009653 - anatomical structure morphogenesis
GO:0016055 - Wnt signaling pathway
GO:0017015 - regulation of transforming growth factor beta receptor signaling pathway
GO:0030325 - adrenal gland development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

312874

GDF11
Growth/differentiation factor 11

2

1

High-throughput

0.628

High

885358

INHBE
Inhibin beta E chain

2

1

High-throughput

0.628

High

172713

LAMA5
Laminin subunit alpha-5

2

0

High-throughput

0.602

High

924428

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

0

High-throughput

0.602

High

1219538

SULF2
Extracellular sulfatase Sulf-2

2

0

High-throughput

0.602

High

1331037

SMOC1
SPARC-related modular calcium-binding protein 1

2

0

High-throughput

0.602

High

297425

MYO1D
Unconventional myosin-Id

2

3

High-throughput

0.574

High

397537

ADT2
ADP/ATP translocase 2

2

1

High-throughput

0.574

High

518517

ADT3
ADP/ATP translocase 3

2

1

High-throughput

0.574

High

557347

GDC
Solute carrier family 25 member 16

2

2

High-throughput

0.574

High

1132846

ATD3C
ATPase family AAA domain-containing protein 3C

2

1

High-throughput

0.574

High

1224804

ASPM
Abnormal spindle-like microcephaly-associated protein

2

6

High-throughput

0.574

High

1293593

SENP5
Sentrin-specific protease 5

2

1

High-throughput

0.574

High

1297269

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

1

High-throughput

0.574

High

1343910

MYO5C
Unconventional myosin-Vc

2

2

High-throughput

0.574

High

1354201

MYO5B
Unconventional myosin-Vb

2

2

High-throughput

0.574

High

1354205

MYO5A
Unconventional myosin-Va

2

3

High-throughput

0.574

High

626275

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

830043

HXA1
Homeobox protein Hox-A1

1

0

High-throughput

0.518

High

1035617

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

1269832

ESR2
Estrogen receptor beta

1

0

High-throughput

0.518

High

135874

WNT7A
Protein Wnt-7a

1

0

High-throughput

0.513

High

173233

VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1

1

0

High-throughput

0.513

High

500180

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

726549

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.513

High

836056

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.513

High

1345042

UBQL4
Ubiquilin-4

1

2

High-throughput

0.494

High

258233

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

70715

MYO9A
Unconventional myosin-IXa

1

4

High-throughput

0.489

High

214687

MYO1B
Unconventional myosin-Ib

1

3

High-throughput

0.489

High

1035149

MYO9B
Unconventional myosin-IXb

1

4

High-throughput

0.489

High

1135360

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.489

High

1293162

P121A
Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.489

High

1349827

SENP1
Sentrin-specific protease 1

1

1

High-throughput

0.489

High

803786

BAG6
Large proline-rich protein BAG6

1

2

High-throughput

0.470

High

135715

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

0

High-throughput

0.328

High

151645

GOSR2
Golgi SNAP receptor complex member 2

2

0

High-throughput

0.328

High

279221

ATP5H
ATP synthase subunit d, mitochondrial

2

0

High-throughput

0.328

High

296578

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

2

0

High-throughput

0.328

High

623396

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

2

0

High-throughput

0.328

High

816124

ATPO
ATP synthase subunit O, mitochondrial

2

0

High-throughput

0.328

High

995277

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.328

High

1000216

IFFO1
Non-homologous end joining factor IFFO1

2

0

High-throughput

0.328

High

1016112

SRBP2
Sterol regulatory element-binding protein 2

2

0

High-throughput

0.328

High

1027587

STX5
Syntaxin-5

2

0

High-throughput

0.328

High

1068965

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.328

High

1108899

MA7D1
MAP7 domain-containing protein 1

2

0

High-throughput

0.328

High

1203065

LONP2
Lon protease homolog 2, peroxisomal

2

0

High-throughput

0.328

High

1245217

TNIP2
TNFAIP3-interacting protein 2

2

0

High-throughput

0.328

High

1272271

GSLG1
Golgi apparatus protein 1

2

0

High-throughput

0.328

High

1309798

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

1344432

CHSTC
Carbohydrate sulfotransferase 12

2

0

High-throughput

0.328

High

1344898

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

0

High-throughput

0.328

High

1354198

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

2

0

High-throughput

0.328

High

1354204

CP131
Centrosomal protein of 131 kDa

2

0

High-throughput

0.328

High

213661

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

0

High-throughput

0.316

High

160826

AURKA
Aurora kinase A

1

0

High-throughput

0.282

High

175406

PPM1D
Protein phosphatase 1D

1

0

High-throughput

0.282

High

275608

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

0

High-throughput

0.282

High

276672

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.282

High

1044230

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.282

High

1189959

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.282

High

155740

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

173138

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.279

Low

215768

GTPB6
Putative GTP-binding protein 6

1

0

High-throughput

0.279

Low

295351

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.279

Low

371290

ATP8
ATP synthase protein 8

1

0

High-throughput

0.279

Low

616567

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.279

Low

1021067

FOXF1
Forkhead box protein F1

1

0

High-throughput

0.279

Low

1204037

CHSS1
Chondroitin sulfate synthase 1

1

0

High-throughput

0.279

Low

1236884

NPW
Neuropeptide W

1

0

High-throughput

0.279

Low

1254013

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.279

Low

1354199

PCOC2
Procollagen C-endopeptidase enhancer 2

1

0

High-throughput

0.279

Low

1354200

PKHH1
Pleckstrin homology domain-containing family H member 1

1

0

High-throughput

0.279

Low

1354203

TTF2
Transcription termination factor 2

1

0

High-throughput

0.279

Low

158049

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

1354202

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.251

Low

522244

CADH1
Cadherin-1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024