Protein: GCYB1
Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)

Gene: GCYB1, GUCY1B1
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q02153

Gene Ontology (top 5):
GO:0004016 - adenylate cyclase activity
GO:0004383 - guanylate cyclase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0006182 - cGMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

969011

GCYA1
Guanylate cyclase soluble subunit alpha-1

4

8

Small-scale

0.898

High

704959

GCYA2
Guanylate cyclase soluble subunit alpha-2

3

8

Small-scale

0.861

High

969048

GCYB1
Guanylate cyclase soluble subunit beta-1

1

8

Small-scale

0.647

High

969052

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

2

5

High-throughput

0.628

High

270617

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

0

High-throughput

0.602

High

969059

NOX5
NADPH oxidase 5

2

0

High-throughput

0.602

High

969063

BBS2
Bardet-Biedl syndrome 2 protein

2

0

High-throughput

0.602

High

969065

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

2

0

High-throughput

0.602

High

952214

MXRA7
Matrix-remodeling-associated protein 7

2

1

High-throughput

0.574

High

431751

HS90A
Heat shock protein HSP 90-alpha

1

4

Small-scale

0.561

High

667677

NOS3
Nitric oxide synthase 3

1

1

Small-scale

0.561

High

969057

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

1

High-throughput

0.536

High

969060

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

3

High-throughput

0.536

High

874006

S12A3
Solute carrier family 12 member 3

1

0

High-throughput

0.513

High

969061

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.513

High

158273

LIN7A
Protein lin-7 homolog A

1

11

High-throughput

0.489

High

233979

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

1

High-throughput

0.489

High

736142

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

3

High-throughput

0.489

High

969054

OR2M7
Olfactory receptor 2M7

1

1

High-throughput

0.489

High

969055

OR1M1
Olfactory receptor 1M1

1

1

High-throughput

0.489

High

969056

OR6T1
Olfactory receptor 6T1

1

2

High-throughput

0.489

High

969058

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.489

High

394561

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

969049

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.479

High

969067

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

Small-scale

0.479

High

969062

GFI1
Zinc finger protein Gfi-1

1

0

Small-scale

0.458

High

217869

PRKY
Putative serine/threonine-protein kinase PRKY

1

1

High-throughput

0.445

High

969051

MTFR2
Mitochondrial fission regulator 2

2

0

High-throughput

0.328

High

71102

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

969064

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

969066

TLR9
Toll-like receptor 9

1

0

High-throughput

0.279

Low

627426

NFYB
Nuclear transcription factor Y subunit beta

1

0

Small-scale

0.249

Low

969050

NFIX
Nuclear factor 1 X-type

1

0

Small-scale

0.249

Low

969053

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

886271

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024