Protein: INT3
Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A)

Gene: INT3, INTS3
Organism: Homo sapiens
Interactions: 127
UniProt ID: Q68E01

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1148337

SOSSC
SOSS complex subunit C

2

0

Small-scale

0.765

High

1148328

SOSB1
SOSS complex subunit B1

7

1

Small-scale

0.752

High

1148344

INT6
Integrator complex subunit 6

6

2

Small-scale

0.740

High

672168

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

3

1

High-throughput

0.671

High

930888

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

1

Small-scale

0.667

High

1148314

SOSB2
SOSS complex subunit B2

3

1

Small-scale

0.656

High

854430

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

3

0

High-throughput

0.628

High

981293

SSBP
Single-stranded DNA-binding protein, mitochondrial

3

0

Small-scale

0.613

High

1148338

INT9
Integrator complex subunit 9

2

1

High-throughput

0.611

High

1148319

CPNE2
Copine-2

2

0

High-throughput

0.602

High

651443

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.586

High

583726

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

High-throughput

0.585

High

676909

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.585

High

854313

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

0

High-throughput

0.585

High

1148309

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.585

High

1148323

INT14
Integrator complex subunit 14

2

0

High-throughput

0.585

High

1135506

INT11
Integrator complex subunit 11

2

1

Small-scale

0.584

High

583500

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.559

High

946645

SSBP2
Single-stranded DNA-binding protein 2

2

0

Small-scale

0.559

High

1148341

INT10
Integrator complex subunit 10

2

0

Small-scale

0.559

High

215903

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.549

High

818148

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.536

High

996709

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1087191

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

71151

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.513

High

123976

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

258068

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

328340

S1PR4
Sphingosine 1-phosphate receptor 4

1

0

High-throughput

0.513

High

362222

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

454713

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

508568

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

564936

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

738849

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

864951

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

897539

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

912161

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.513

High

948805

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

1021303

FOXL1
Forkhead box protein L1

1

0

High-throughput

0.513

High

1039626

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1061140

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1075236

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1148315

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1148324

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1148327

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1148330

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1148333

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

1030960

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1148331

DNAI2
Dynein axonemal intermediate chain 2

1

1

High-throughput

0.489

High

394918

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

902630

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

1148346

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

268142

EED
Polycomb protein EED

1

2

High-throughput

0.479

High

377398

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

672435

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.479

High

915219

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.479

High

918437

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1127510

INT6L
Integrator complex subunit 6-like

1

2

High-throughput

0.479

High

1148305

ZN687
Zinc finger protein 687

1

1

High-throughput

0.479

High

1148312

ZN592
Zinc finger protein 592

1

1

High-throughput

0.479

High

1148313

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1148322

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

1148336

WDR76
WD repeat-containing protein 76

1

1

High-throughput

0.479

High

181424

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

244563

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

274103

XRP2
Protein XRP2

1

0

High-throughput

0.458

High

504236

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

552942

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

587609

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.458

High

624928

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

681898

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.458

High

720686

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

824102

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

841236

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

848864

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.458

High

903296

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

913904

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

917432

H4
Histone H4

1

0

High-throughput

0.458

High

941035

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1018988

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1038125

ATR
Serine/threonine-protein kinase ATR

1

0

Small-scale

0.458

High

1041788

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1057287

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.458

High

1063448

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1064401

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1080035

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1148296

NAIF1
Nuclear apoptosis-inducing factor 1

1

0

High-throughput

0.458

High

1148297

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1148298

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

1148300

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1148301

INT8
Integrator complex subunit 8

1

0

High-throughput

0.458

High

1148302

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1148304

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.458

High

1148306

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

1148307

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

1148311

ATRIP
ATR-interacting protein

1

0

Small-scale

0.458

High

1148316

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1148317

INT12
Integrator complex subunit 12

1

0

High-throughput

0.458

High

1148320

INT4
Integrator complex subunit 4

1

0

High-throughput

0.458

High

1148321

INT15
Integrator complex subunit 15

1

0

High-throughput

0.458

High

1148332

INT2
Integrator complex subunit 2

1

0

High-throughput

0.458

High

1148335

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1148339

INT7
Integrator complex subunit 7

1

0

High-throughput

0.458

High

1148340

INT13
Integrator complex subunit 13

1

0

High-throughput

0.458

High

1148342

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1148345

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

798429

LPAR6
Lysophosphatidic acid receptor 6

1

1

High-throughput

0.437

High

135261

E2F3
Transcription factor E2F3

1

0

Small-scale

0.426

High

867602

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.426

High

1148325

CDX2
Homeobox protein CDX-2

1

0

High-throughput

0.426

High

217901

PRKY
Putative serine/threonine-protein kinase PRKY

1

1

High-throughput

0.407

High

1148303

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.347

High

551405

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

0

High-throughput

0.328

High

702235

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1148310

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

238872

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

300672

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

318490

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.279

Low

813062

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

1148299

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1148308

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1148326

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.279

Low

1148329

TX13B
Testis-expressed protein 13B

1

0

High-throughput

0.279

Low

1148334

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

1148343

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1148347

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

384997

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1148318

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024