Protein: PHAR4
Phosphatase and actin regulator 4

Gene: PHAR4, PHACTR4
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q8IZ21

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0001843 - neural tube closure
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0007266 - Rho protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

891891

ACTB
Actin, cytoplasmic 1

2

20

High-throughput

0.789

High

737916

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

12

Small-scale

0.695

High

929922

ACTG
Actin, cytoplasmic 2

1

20

High-throughput

0.691

High

906013

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

12

High-throughput

0.667

High

932253

ACTC
Actin, alpha cardiac muscle 1

1

18

High-throughput

0.665

High

647096

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

683531

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.650

High

904838

1433G
14-3-3 protein gamma

3

20

High-throughput

0.650

High

909796

1433E
14-3-3 protein epsilon

3

6

High-throughput

0.650

High

927287

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.650

High

982258

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

350328

RASK
GTPase KRas

3

12

High-throughput

0.640

High

157464

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

2

10

High-throughput

0.628

High

456238

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

2

7

High-throughput

0.628

High

456288

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

2

10

High-throughput

0.628

High

1223919

RAB9B
Ras-related protein Rab-9B

3

7

High-throughput

0.609

High

349463

RASH
GTPase HRas

2

9

High-throughput

0.584

High

507114

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

547131

EZRI
Ezrin

2

10

High-throughput

0.584

High

716729

CTNA1
Catenin alpha-1

2

4

Small-scale

0.584

High

915819

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

1118862

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

3

High-throughput

0.574

High

1223909

BCL7C
B-cell CLL/lymphoma 7 protein family member C

2

3

High-throughput

0.574

High

802653

CRK
Adapter molecule crk

2

20

High-throughput

0.571

High

200406

HS12A
Heat shock 70 kDa protein 12A

1

1

High-throughput

0.536

High

1158546

L2GL2
LLGL scribble cell polarity complex component 2

1

3

High-throughput

0.536

High

348771

RASN
GTPase NRas

2

12

High-throughput

0.533

High

871659

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

930292

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.513

High

1219660

RHG12
Rho GTPase-activating protein 12

1

0

High-throughput

0.513

High

1223920

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

395153

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

323882

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.489

High

330693

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

2

High-throughput

0.489

High

924692

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.481

High

120529

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

279630

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

433883

LYN
Tyrosine-protein kinase Lyn

1

15

High-throughput

0.479

High

434236

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

11

High-throughput

0.479

High

522050

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

545487

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

567158

CXA1
Gap junction alpha-1 protein

1

4

High-throughput

0.479

High

592363

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

608039

FGFR4
Fibroblast growth factor receptor 4

1

11

High-throughput

0.479

High

670107

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

840519

VASP
Vasodilator-stimulated phosphoprotein

1

6

High-throughput

0.479

High

881529

ARL4C
ADP-ribosylation factor-like protein 4C

1

4

High-throughput

0.479

High

892476

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894200

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

900673

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

901198

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

925424

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

940488

CXAR
Coxsackievirus and adenovirus receptor

1

4

High-throughput

0.479

High

951142

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

974914

CAV1
Caveolin-1

1

5

High-throughput

0.479

High

1017699

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1076655

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1223911

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.479

High

1223914

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

1223916

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1223918

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.479

High

1223922

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

71178

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

6

High-throughput

0.470

High

1223923

RALY
RNA-binding protein Raly

1

4

High-throughput

0.470

High

173596

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

132529

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

146051

CLD4
Claudin-4

1

2

Small-scale

0.437

High

178649

STX7
Syntaxin-7

1

3

High-throughput

0.437

High

198276

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

2

High-throughput

0.437

High

212919

STX6
Syntaxin-6

1

4

High-throughput

0.437

High

305534

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

411787

LCK
Tyrosine-protein kinase Lck

1

15

High-throughput

0.437

High

435693

IGF1R
Insulin-like growth factor 1 receptor

1

12

High-throughput

0.437

High

508094

FGFR1
Fibroblast growth factor receptor 1

1

11

High-throughput

0.437

High

564605

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.437

High

665626

EPHB2
Ephrin type-B receptor 2

1

9

High-throughput

0.437

High

793385

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.437

High

876438

AFAD
Afadin

1

12

High-throughput

0.437

High

884534

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.437

High

914200

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.437

High

968428

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

11

High-throughput

0.437

High

1070288

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.437

High

1084088

OCLN
Occludin

1

4

High-throughput

0.437

High

1110020

AR13B
ADP-ribosylation factor-like protein 13B

1

2

High-throughput

0.437

High

1151959

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1183456

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.437

High

1203761

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1223907

ARL14
ADP-ribosylation factor-like protein 14

1

1

High-throughput

0.437

High

1223908

PARD3
Partitioning defective 3 homolog

1

5

High-throughput

0.437

High

1223910

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1223912

SCLT1
Sodium channel and clathrin linker 1

1

10

High-throughput

0.437

High

1223915

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.437

High

1223917

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.437

High

1223921

ARL15
ADP-ribosylation factor-like protein 15

1

1

High-throughput

0.437

High

337500

ABL1
Tyrosine-protein kinase ABL1

1

15

High-throughput

0.408

High

147770

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

0

High-throughput

0.328

High

912986

ARF6
ADP-ribosylation factor 6

2

0

High-throughput

0.305

High

1223913

FMNL2
Formin-like protein 2

1

0

High-throughput

0.269

Low

224473

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.249

Low

577040

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024