HitPredict - High confidence protein-protein interactions

Protein: PSN1
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]

Gene: PSN1, Psen1
Organism: Rattus norvegicus
Interactions: 8
UniProt ID: P97887

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000776 - kinetochore
GO:0001568 - blood vessel development

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
957068	Q5PQQ3 Gamma-secretase subunit APH-1	2	10	Small-scale	0.737	High
957067	PSN1 Presenilin-1	1	7	Small-scale	0.618	High
957069	PEN2 Gamma-secretase subunit PEN-2	1	7	Small-scale	0.575	High
78159	ERLN2 Erlin-2	1	1	Small-scale	0.536	High
421809	TNR16 Tumor necrosis factor receptor superfamily member 16	1	1	Small-scale	0.515	High
957070	NICA Nicastrin	1	6	Small-scale	0.479	High
600319	SYT1 Synaptotagmin-1	1	1	Small-scale	0.445	High

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024