Protein: GCH1
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)

Gene: GCH1, cat-4
Organism: Caenorhabditis elegans
Interactions: 15
UniProt ID: Q19980

Gene Ontology (top 5):
GO:0003934 - GTP cyclohydrolase I activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0006585 - dopamine biosynthetic process from tyrosine
GO:0006729 - tetrahydrobiopterin biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1167016

GCH1
GTP cyclohydrolase 1

1

7

Small-scale

0.590

High

107595

G1K0W3
PDZ domain-containing protein

1

1

High-throughput

0.504

High

1167017

Q20232
Arrestin C-terminal-like domain-containing protein

1

1

High-throughput

0.494

High

1167019

Q8MQ71
SH3 domain-containing protein

1

0

High-throughput

0.486

High

1167020

Q95XA9
SH2 domain-containing protein

1

0

High-throughput

0.486

High

92050

D1MN74
Arrestin C-terminal-like domain-containing protein

1

1

High-throughput

0.481

High

1165815

Q18204
SH3 domain-containing protein

1

2

High-throughput

0.464

High

1167024

CLA1
Protein clarinet

1

1

High-throughput

0.462

High

111286

G5ECZ8
PDZ domain-containing protein

1

1

High-throughput

0.417

High

1167018

YW12
UPF0046 protein T07D4.2

1

0

High-throughput

0.304

High

1167021

Q9GPA1
Peptidase S1 domain-containing protein

1

0

High-throughput

0.292

High

1167023

Q9TZ84
Ubiquitin-like domain-containing protein

1

0

High-throughput

0.292

High

1167022

Q9GZG8
G-protein coupled receptors family 1 profile domain-containing protein

1

0

High-throughput

0.282

High

113143

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025