Protein: MRT2
Cell cycle checkpoint protein RAD1 homolog mrt-2 (EC 3.1.11.2)

Gene: MRT2, mrt-2
Organism: Caenorhabditis elegans
Interactions: 68
UniProt ID: G5EC44

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000723 - telomere maintenance
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

110563

G5EFI9
Checkpoint protein

5

5

Small-scale

0.937

High

110618

HPR9
Cell cycle checkpoint protein hpr-9

3

5

High-throughput

0.847

High

110569

FIGL1
Fidgetin-like protein 1

1

3

High-throughput

0.698

High

110591

TERA1
Transitional endoplasmic reticulum ATPase homolog 1

1

2

High-throughput

0.698

High

110567

PCNA
Proliferating cell nuclear antigen

3

17

High-throughput

0.668

High

110613

PSB3
Proteasome subunit beta type-3

3

3

High-throughput

0.635

High

110566

H2KYP7
pantothenate kinase

3

0

High-throughput

0.608

High

110587

TCPA
T-complex protein 1 subunit alpha

3

0

High-throughput

0.608

High

110620

Q9GYG1
C2H2-type domain-containing protein

2

0

Small-scale

0.593

High

110564

G5EFS1
Death domain-containing protein

3

3

High-throughput

0.580

High

110582

CALR
Calreticulin

3

1

High-throughput

0.580

High

110596

Q17746
ZZ-type domain-containing protein

3

2

High-throughput

0.580

High

110597

PDI2
Protein disulfide-isomerase 2

3

3

High-throughput

0.580

High

110573

NH213
Nuclear hormone receptor family member nhr-213

1

2

High-throughput

0.541

High

110575

O44635
Nuclear Hormone Receptor family

1

2

High-throughput

0.541

High

110576

NH111
Nuclear hormone receptor family member nhr-111

1

3

High-throughput

0.541

High

110614

Q23345
Serine/threonine specific protein phosphatases domain-containing protein

1

4

High-throughput

0.541

High

110626

Q9U395
Serine/threonine-protein phosphatase

1

4

High-throughput

0.541

High

110625

Q9U2G8
SPK domain-containing protein

2

1

High-throughput

0.526

High

110565

BRC2
DNA repair protein brc-2

1

0

High-throughput

0.518

High

110579

O45934
Phosphoglucomutase-2

1

0

High-throughput

0.518

High

110583

TBP
TATA-box-binding protein

1

0

High-throughput

0.518

High

110589

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.518

High

110598

Q17971
Proteasome activator complex subunit 4

1

0

High-throughput

0.518

High

110568

IFA2
Intermediate filament protein ifa-2

1

1

High-throughput

0.494

High

110570

O17030
G-protein coupled receptors family 1 profile domain-containing protein

1

1

High-throughput

0.494

High

110578

O45815
Actin

1

1

High-throughput

0.494

High

110601

Q18426
TPR_REGION domain-containing protein

1

2

High-throughput

0.494

High

110615

CUL5
Cullin-5

1

8

High-throughput

0.494

High

110622

Q9TYX4
Tyrosine-protein kinase

1

2

High-throughput

0.494

High

98544

F1LIM5
ZZ-type domain-containing protein

1

2

High-throughput

0.439

High

110616

MEC2
Mechanosensory protein 2

1

2

High-throughput

0.439

High

110609

Q22436
ZZ-type domain-containing protein

1

2

High-throughput

0.417

High

110584

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

3

0

High-throughput

0.340

High

110600

Q18320
Suppressor of ZYg-1

3

0

High-throughput

0.340

High

110605

Q20398
PDZ domain-containing protein

3

0

High-throughput

0.340

High

110608

Q22055
RING-type domain-containing protein

3

0

High-throughput

0.340

High

110603

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

3

0

High-throughput

0.331

High

110607

Q21285
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.292

High

110571

NMUR2
Neuromedin U receptor homolog nmur-2

1

0

High-throughput

0.282

High

110572

O17526
aralkylamine N-acetyltransferase

1

0

High-throughput

0.282

High

110574

O44606

1

0

High-throughput

0.282

High

110577

O45603
MEiosis-to-MItosis transition associated

1

0

High-throughput

0.282

High

110580

O62468
RNA-binding protein

1

0

High-throughput

0.282

High

110581

MYO4
Myosin-4

1

0

High-throughput

0.282

High

110585

FAHD1
Oxaloacetate tautomerase fahd-1, mitochondrial

1

0

High-throughput

0.282

High

110586

WNT1
Protein Wnt-1

1

0

High-throughput

0.282

High

110588

ZTF17
Zinc finger transcription factor family protein 17

1

0

High-throughput

0.282

High

110590

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1

1

0

High-throughput

0.282

High

110592

P91126
Uncharacterized protein

1

0

High-throughput

0.282

High

110593

P91551
Serpentine Receptor, class I

1

0

High-throughput

0.282

High

110594

Q09479
Major facilitator superfamily

1

0

High-throughput

0.282

High

110595

GADR3
Gastrulation-defective protein 3

1

0

High-throughput

0.282

High

110599

Q18157
TIL domain-containing protein

1

0

High-throughput

0.282

High

110602

Q19120
Ground-like domain-containing protein

1

0

High-throughput

0.282

High

110604

Q19739
CHp/Wrch Rho-like protein homolog

1

0

High-throughput

0.282

High

110606

Q20611
Fatty acid hydroxylase domain-containing protein

1

0

High-throughput

0.282

High

110610

Q22660
Major sperm protein

1

0

High-throughput

0.282

High

110611

Q22694
Major sperm protein

1

0

High-throughput

0.282

High

110612

Q23182
F-box associated domain-containing protein

1

0

High-throughput

0.282

High

110619

Q95YC6
Neuropeptide-Like Protein

1

0

High-throughput

0.282

High

110621

ZFPL1
Zinc finger protein-like 1 homolog

1

0

High-throughput

0.282

High

110623

Q9TZA5
G protein-coupled receptor

1

0

High-throughput

0.282

High

110624

Q9U1V2
Armadillo repeat-containing domain-containing protein

1

0

High-throughput

0.282

High

110627

Q9XVP7
Sperm-Specific family, class S

1

0

High-throughput

0.282

High

110628

ELOF1
Transcription elongation factor 1 homolog

1

0

High-throughput

0.282

High

110629

Q9XXH0
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.282

High

110617

RPI1
Protein rpi-1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025