HitPredict

Interactor 1: MRT2 (G5EC44)
Cell cycle checkpoint protein RAD1 homolog mrt-2 (EC 3.1.11.2)
Gene: mrt-2

Interactor 2: PCNA (O02115)
Proliferating cell nuclear antigen (PCNA)
Gene: pcn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.668

Property	Details
Experiments	12679813, 11778048, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 267 Ce			1 263
+	Bt
		1191825 PCNA_BOVIN (1-267): 8.85e-92: 273: 14.96		PCNA_BOVIN (1-260): 6.09e-110: 319: 47.69
+	Cg
		945507 PCNA_CRIGR (1-267): 8.47e-91: 271: 14.96		PCNA_CRIGR (1-260): 8e-110: 319: 48.08
+	Hs
		550811 PCNA_HUMAN (1-267): 3.42e-91: 271: 14.96		PCNA_HUMAN (1-260): 1.51e-109: 318: 48.08
+	Dm
		609351 PCNA_DROME (1-267): 1.61e-89: 267: 18.25		PCNA_DROME (1-261): 1.22e-109: 318: 47.89
+	At
		1444633 PCNA1_ARATH (1-267): 1.19e-88: 265: 18.61		PCNA1_ARATH (1-263): 7.47e-109: 316: 51.71
+	At
		1444635 PCNA1_ARATH (1-267): 1.19e-88: 265: 18.61		PCNA2_ARATH (1-262): 8.69e-107: 311: 50.38
+	At
		1492056 PCNA2_ARATH (1-267): 3.72e-87: 261: 18.98		PCNA2_ARATH (1-262): 8.69e-107: 311: 50.38
+	Dm
		609463 PCNA_DROME (1-267): 1.61e-89: 267: 18.25		PCNA2_DROME (1-260): 6.39e-97: 286: 41.15
+	Ce
		145633 PCNA_CAEEL (1-267): 5.56e-78: 238: 15.33		PCNA_CAEEL (1-263): 2e-102: 300: 100.00
+	Sp
		1042570 PCNA_SCHPO (1-267): 1.14e-78: 240: 17.52		PCNA_SCHPO (1-261): 4.55e-99: 291: 49.04
+	Dm
		1477767 PCNA2_DROME (1-266): 7.94e-81: 245: 17.54		PCNA2_DROME (1-260): 6.39e-97: 286: 41.15
+	Ca
		1202906 Q5AMN0_CANAL (1-267): 1.95e-70: 219: 17.95		Q5AMN0_CANAL (1-260): 1.4e-91: 272: 43.46
+	Sc
		586422 PCNA_YEAST (1-267): 1.59e-68: 214: 16.61		PCNA_YEAST (1-260): 3.24e-92: 274: 40.39
+	Hs
		253179 RAD1_HUMAN (16-265): 6.11e-80: 244: 28.79		RAD1_HUMAN (2-261): 7.4e-68: 213: 13.97
+	Dm
		1484098 RAD1_DROME (6-267): 2.56e-72: 224: 21.56		RAD1_DROME (2-259): 1.4e-62: 199: 15.13
+	Tk
		1205588 PCNA1_THEKO (12-266): 8.17e-53: 173: 20.16		PCNA1_THEKO (2-258): 7.65e-76: 232: 22.57
+	Tk
		1205593 PCNA2_THEKO (12-266): 9.84e-34: 124: 15.83		PCNA2_THEKO (2-258): 3.58e-75: 230: 20.93