Protein: PAR6B
Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)

Gene: PAR6B, PARD6B
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q9BYG5

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

983913

KPCZ
Protein kinase C zeta type

14

16

Small-scale

0.986

High

784081

KPCI
Protein kinase C iota type

14

16

Small-scale

0.985

High

894391

CDC42
Cell division control protein 42 homolog

9

20

Small-scale

0.982

High

1316964

RHOJ
Rho-related GTP-binding protein RhoJ

7

20

High-throughput

0.968

High

1256880

PARD3
Partitioning defective 3 homolog

8

20

Small-scale

0.967

High

564670

RHOQ
Rho-related GTP-binding protein RhoQ

4

20

Small-scale

0.893

High

925587

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

Small-scale

0.821

High

1316957

PAR6G
Partitioning defective 6 homolog gamma

2

12

High-throughput

0.811

High

1316970

PAR6A
Partitioning defective 6 homolog alpha

2

15

High-throughput

0.811

High

1301554

TRIB3
Tribbles homolog 3

2

3

High-throughput

0.783

High

892572

RAC3
Ras-related C3 botulinum toxin substrate 3

2

20

High-throughput

0.776

High

1158573

L2GL2
LLGL scribble cell polarity complex component 2

8

8

Small-scale

0.755

High

1071568

L2GL1
Lethal(2) giant larvae protein homolog 1

6

8

High-throughput

0.735

High

906113

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

High-throughput

0.691

High

1043746

ASPP2
Apoptosis-stimulating of p53 protein 2

1

3

High-throughput

0.691

High

1312690

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

8

High-throughput

0.691

High

1316968

ROBO2
Roundabout homolog 2

1

2

High-throughput

0.691

High

1316977

ROBO1
Roundabout homolog 1

1

2

High-throughput

0.691

High

1076915

PTN14
Tyrosine-protein phosphatase non-receptor type 14

3

13

High-throughput

0.667

High

1220082

KIBRA
Protein KIBRA

3

17

High-throughput

0.667

High

1262062

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

6

High-throughput

0.667

High

1294535

GMCL1
Germ cell-less protein-like 1

3

4

High-throughput

0.654

High

1251530

CEP76
Centrosomal protein of 76 kDa

3

0

High-throughput

0.646

High

982453

1433F
14-3-3 protein eta

2

15

High-throughput

0.628

High

374827

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.618

High

901233

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

951299

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1296728

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1316966

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

195750

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

3

2

High-throughput

0.609

High

1087930

PTN21
Tyrosine-protein phosphatase non-receptor type 21

3

15

High-throughput

0.609

High

1133257

HECD3
E3 ubiquitin-protein ligase HECTD3

3

9

High-throughput

0.609

High

1237781

ARL10
ADP-ribosylation factor-like protein 10

3

3

High-throughput

0.609

High

1239110

ZSCA4
Zinc finger and SCAN domain-containing protein 4

2

6

High-throughput

0.606

High

1283679

MGN2
Protein mago nashi homolog 2

2

1

High-throughput

0.606

High

1298647

FRMD6
FERM domain-containing protein 6

2

20

High-throughput

0.606

High

1316975

TRI35
E3 ubiquitin-protein ligase TRIM35

2

4

High-throughput

0.606

High

228591

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

253178

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1203192

RASF3
Ras association domain-containing protein 3

2

0

High-throughput

0.580

High

1315469

CDCA4
Cell division cycle-associated protein 4

2

0

High-throughput

0.580

High

99492

F5GZI3
Par-3 family cell polarity regulator

1

20

High-throughput

0.575

High

995203

GOGA2
Golgin subfamily A member 2

1

3

High-throughput

0.573

High

370366

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

1312846

CRUM3
Protein crumbs homolog 3

1

6

Small-scale

0.561

High

1216701

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.560

High

1245840

RASF8
Ras association domain-containing protein 8

2

4

High-throughput

0.558

High

295557

RECQ5
ATP-dependent DNA helicase Q5

1

1

High-throughput

0.536

High

453591

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.536

High

647244

1433T
14-3-3 protein theta

1

15

High-throughput

0.536

High

909989

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

927488

1433Z
14-3-3 protein zeta/delta

1

15

High-throughput

0.536

High

993343

FOXM1
Forkhead box protein M1

1

4

High-throughput

0.536

High

1294474

LRCH3
DISP complex protein LRCH3

1

3

High-throughput

0.536

High

1309726

SLF1
SMC5-SMC6 complex localization factor protein 1

1

3

High-throughput

0.536

High

1314330

KIFC1
Kinesin-like protein KIFC1

1

6

High-throughput

0.536

High

1316963

E41LB
Band 4.1-like protein 4B

1

16

High-throughput

0.536

High

1316969

MYO10
Unconventional myosin-X

1

2

High-throughput

0.536

High

1316974

ICAM5
Intercellular adhesion molecule 5

1

7

High-throughput

0.536

High

1316976

DLGP4
Disks large-associated protein 4

1

8

High-throughput

0.536

High

1310797

WDR83
WD repeat domain-containing protein 83

1

2

Small-scale

0.523

High

1121908

Q53SE7
Germ cell-less homolog 1

1

4

High-throughput

0.515

High

116621

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.513

High

277542

CCNK
Cyclin-K

1

0

High-throughput

0.513

High

296973

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.513

High

299788

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

330519

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

549102

GNS
N-acetylglucosamine-6-sulfatase

1

0

High-throughput

0.513

High

685341

I5P2
Type II inositol 1,4,5-trisphosphate 5-phosphatase

1

0

High-throughput

0.513

High

801551

KPB1
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform

1

0

High-throughput

0.513

High

885022

SELB
Selenocysteine-specific elongation factor

1

0

High-throughput

0.513

High

1081896

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

High-throughput

0.513

High

1219639

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.513

High

1241982

MSD4
Myb/SANT-like DNA-binding domain-containing protein 4

1

0

High-throughput

0.513

High

1305171

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.513

High

1316971

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1316972

DMBT1
Deleted in malignant brain tumors 1 protein

1

0

High-throughput

0.513

High

1316973

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.513

High

175174

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

395692

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

129423

GOLI4
Golgi integral membrane protein 4

1

1

High-throughput

0.489

High

532205

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.489

High

966193

NC2B
Protein Dr1

1

1

High-throughput

0.489

High

1231920

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

3

High-throughput

0.489

High

1316965

IFT22
Intraflagellar transport protein 22 homolog

1

2

High-throughput

0.489

High

1262754

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

1

Small-scale

0.481

High

507217

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.479

High

577062

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

High-throughput

0.479

High

648875

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

958119

RBM10
RNA-binding protein 10

1

3

High-throughput

0.479

High

1075743

SF01
Splicing factor 1

1

1

High-throughput

0.479

High

1201301

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

6

High-throughput

0.479

High

1269537

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

418625

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

545029

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

1242292

PNMA1
Paraneoplastic antigen Ma1

1

5

High-throughput

0.437

High

1238513

BANP
Protein BANP

2

0

High-throughput

0.316

High

1166758

TMM92
Transmembrane protein 92

1

0

High-throughput

0.279

Low

1192713

RM55
Large ribosomal subunit protein mL55

1

0

High-throughput

0.279

Low

1223563

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low

1239793

AVL9
Late secretory pathway protein AVL9 homolog

1

0

High-throughput

0.279

Low

1284708

EME1
Crossover junction endonuclease EME1

1

0

High-throughput

0.279

Low

1295771

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.279

Low

1316967

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1132842

ATD3C
ATPase family AAA domain-containing protein 3C

1

0

High-throughput

0.249

Low

110826

H7C0N4
Splicing factor 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024