Protein: KPCD1
Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)

Gene: KPCD1, PRKD1
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q15139

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646908

1433T
14-3-3 protein theta

4

20

Small-scale

0.893

High

927067

1433Z
14-3-3 protein zeta/delta

4

20

Small-scale

0.893

High

1068460

KPCD1
Serine/threonine-protein kinase D1

4

16

Small-scale

0.885

High

296520

KPCD3
Serine/threonine-protein kinase D3

3

15

High-throughput

0.871

High

1068504

KPCD2
Serine/threonine-protein kinase D2

3

17

High-throughput

0.861

High

909585

1433E
14-3-3 protein epsilon

3

7

High-throughput

0.839

High

273520

ADAP1
Arf-GAP with dual PH domain-containing protein 1

1

20

Small-scale

0.771

High

162055

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

2

15

High-throughput

0.737

High

273434

PPM1B
Protein phosphatase 1B

2

8

High-throughput

0.737

High

433357

YES
Tyrosine-protein kinase Yes

2

13

High-throughput

0.737

High

609876

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

10

High-throughput

0.737

High

613463

SFPQ
Splicing factor, proline- and glutamine-rich

2

6

High-throughput

0.737

High

726831

FUS
RNA-binding protein FUS

2

5

High-throughput

0.737

High

822025

KC1A
Casein kinase I isoform alpha

2

12

High-throughput

0.737

High

904582

1433G
14-3-3 protein gamma

2

20

High-throughput

0.737

High

920972

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

6

High-throughput

0.737

High

921571

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

2

6

High-throughput

0.737

High

963988

SRSF2
Serine/arginine-rich splicing factor 2

2

8

High-throughput

0.737

High

982031

1433F
14-3-3 protein eta

2

20

High-throughput

0.737

High

1020431

TRAP1
Heat shock protein 75 kDa, mitochondrial

2

8

High-throughput

0.737

High

1030253

G3BP1
Ras GTPase-activating protein-binding protein 1

2

1

High-throughput

0.737

High

1068462

NONO
Non-POU domain-containing octamer-binding protein

2

11

High-throughput

0.737

High

1068465

CDC37
Hsp90 co-chaperone Cdc37

2

8

High-throughput

0.737

High

1068480

KC1AL
Casein kinase I isoform alpha-like

2

16

High-throughput

0.737

High

1068497

UHRF1
E3 ubiquitin-protein ligase UHRF1

2

4

High-throughput

0.737

High

173891

MK13
Mitogen-activated protein kinase 13

1

20

Small-scale

0.734

High

986377

BTK
Tyrosine-protein kinase BTK

1

13

Small-scale

0.724

High

1016912

AKP13
A-kinase anchor protein 13

1

11

Small-scale

0.724

High

969083

KPCE
Protein kinase C epsilon type

1

17

Small-scale

0.692

High

1068473

MARK2
Serine/threonine-protein kinase MARK2

1

13

Small-scale

0.692

High

1068499

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

17

High-throughput

0.691

High

1068520

ZN777
Zinc finger protein 777

1

2

High-throughput

0.691

High

388459

HSPB1
Heat shock protein beta-1

4

11

Small-scale

0.686

High

1068521

HDAC5
Histone deacetylase 5

4

17

Small-scale

0.676

High

438186

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.665

High

267578

RMXL2
RNA-binding motif protein, X-linked-like-2

2

7

High-throughput

0.659

High

1068516

ZO2
Tight junction protein ZO-2

3

12

High-throughput

0.650

High

1068514

IBTK
Inhibitor of Bruton tyrosine kinase

1

8

Small-scale

0.648

High

1068463

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

2

18

High-throughput

0.628

High

990071

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

Small-scale

0.618

High

326649

SNAI1
Zinc finger protein SNAI1

1

2

Small-scale

0.618

High

431868

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

562647

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

5

Small-scale

0.618

High

581009

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

5

Small-scale

0.618

High

796579

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

800783

MK08
Mitogen-activated protein kinase 8

1

20

Small-scale

0.618

High

800889

MK09
Mitogen-activated protein kinase 9

1

20

Small-scale

0.618

High

983840

KPCZ
Protein kinase C zeta type

1

18

High-throughput

0.618

High

1068472

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

1068483

SNX33
Sorting nexin-33

1

5

High-throughput

0.618

High

1068506

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1068522

FBW1A
F-box/WD repeat-containing protein 1A

1

9

Small-scale

0.618

High

402037

JUN
Transcription factor Jun

2

4

Small-scale

0.602

High

1068507

SIX2
Homeobox protein SIX2

2

0

High-throughput

0.602

High

1068493

PP14A
Protein phosphatase 1 regulatory subunit 14A

1

2

Small-scale

0.598

High

667758

NOS1
Nitric oxide synthase 1

1

4

Small-scale

0.586

High

375810

FUCO
Tissue alpha-L-fucosidase

2

1

High-throughput

0.574

High

117705

MYO1C
Unconventional myosin-Ic

2

17

High-throughput

0.571

High

124615

CLIC1
Chloride intracellular channel protein 1

2

1

High-throughput

0.571

High

131653

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

2

5

High-throughput

0.571

High

214582

MYO1B
Unconventional myosin-Ib

2

17

High-throughput

0.571

High

225878

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

14

High-throughput

0.571

High

234219

PEPL
Periplakin

2

18

High-throughput

0.571

High

262821

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.571

High

270922

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

2

4

High-throughput

0.571

High

297349

MYO1D
Unconventional myosin-Id

2

17

High-throughput

0.571

High

313828

SVIL
Supervillin

2

4

High-throughput

0.571

High

391399

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

2

5

High-throughput

0.571

High

418963

TPM3
Tropomyosin alpha-3 chain

2

8

High-throughput

0.571

High

444894

ANXA5
Annexin A5

2

6

High-throughput

0.571

High

457109

LKHA4
Leukotriene A-4 hydrolase

2

3

High-throughput

0.571

High

515860

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

14

High-throughput

0.571

High

551713

DESP
Desmoplakin

2

12

High-throughput

0.571

High

604160

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

2

1

High-throughput

0.571

High

643865

SYVC
Valine--tRNA ligase

2

6

High-throughput

0.571

High

657612

ITPI2
Protein ITPRID2

2

1

High-throughput

0.571

High

671574

KCY
UMP-CMP kinase

2

4

High-throughput

0.571

High

708650

MCM5
DNA replication licensing factor MCM5

2

9

High-throughput

0.571

High

708919

MCM7
DNA replication licensing factor MCM7

2

9

High-throughput

0.571

High

722607

T2FA
General transcription factor IIF subunit 1

2

1

High-throughput

0.571

High

750840

VATA
V-type proton ATPase catalytic subunit A

2

8

High-throughput

0.571

High

814081

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

2

1

High-throughput

0.571

High

814375

AL1A3
Retinaldehyde dehydrogenase 3

2

1

High-throughput

0.571

High

829379

SYSC
Serine--tRNA ligase, cytoplasmic

2

1

High-throughput

0.571

High

843686

FXR1
RNA-binding protein FXR1

2

12

High-throughput

0.571

High

844073

FXR2
RNA-binding protein FXR2

2

12

High-throughput

0.571

High

862396

ACLY
ATP-citrate synthase

2

2

High-throughput

0.571

High

893355

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

14

High-throughput

0.571

High

905912

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

14

High-throughput

0.571

High

926687

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

2

5

High-throughput

0.571

High

961978

DHSO
Sorbitol dehydrogenase

2

1

High-throughput

0.571

High

973763

AKA12
A-kinase anchor protein 12

2

7

High-throughput

0.571

High

1048586

DSG2
Desmoglein-2

2

7

High-throughput

0.571

High

1055329

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

14

High-throughput

0.571

High

1055733

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

2

8

High-throughput

0.571

High

1058211

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

5

High-throughput

0.571

High

1068461

PLEC
Plectin

2

7

High-throughput

0.571

High

1068464

ZYX
Zyxin

2

12

High-throughput

0.571

High

1068469

UBR4
E3 ubiquitin-protein ligase UBR4

2

7

High-throughput

0.571

High

1068474

DHX30
ATP-dependent RNA helicase DHX30

2

1

High-throughput

0.571

High

1068477

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

2

1

High-throughput

0.571

High

1068479

CCAR2
Cell cycle and apoptosis regulator protein 2

2

3

High-throughput

0.571

High

1068486

AP3S1
AP-3 complex subunit sigma-1

2

1

High-throughput

0.571

High

1068490

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

5

High-throughput

0.571

High

1068491

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

2

High-throughput

0.571

High

1068500

GDF15
Growth/differentiation factor 15

2

1

High-throughput

0.571

High

1068508

MYO5C
Unconventional myosin-Vc

2

7

High-throughput

0.571

High

1068509

DDX21
Nucleolar RNA helicase 2

2

6

High-throughput

0.571

High

1068513

MAT2B
Methionine adenosyltransferase 2 subunit beta

2

2

High-throughput

0.571

High

1068519

ACSL5
Long-chain-fatty-acid--CoA ligase 5

2

3

High-throughput

0.571

High

1068523

PKP3
Plakophilin-3

2

8

High-throughput

0.571

High

1068524

MYO5A
Unconventional myosin-Va

2

13

High-throughput

0.571

High

1068525

NS1BP
Influenza virus NS1A-binding protein

2

4

High-throughput

0.571

High

521941

CADH1
Cadherin-1

1

6

Small-scale

0.561

High

1068495

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

7

Small-scale

0.561

High

1068515

CSN7A
COP9 signalosome complex subunit 7a

1

3

Small-scale

0.561

High

365273

MT2
Metallothionein-2

1

0

Small-scale

0.558

High

128733

RTCA
RNA 3'-terminal phosphate cyclase

2

0

High-throughput

0.547

High

200565

CP110
Centriolar coiled-coil protein of 110 kDa

2

0

High-throughput

0.547

High

268994

CSDE1
Cold shock domain-containing protein E1

2

0

High-throughput

0.547

High

335674

COX1
Cytochrome c oxidase subunit 1

2

0

High-throughput

0.547

High

341503

UROK
Urokinase-type plasminogen activator

2

0

High-throughput

0.547

High

378697

KITH
Thymidine kinase, cytosolic

2

0

High-throughput

0.547

High

430468

APT
Adenine phosphoribosyltransferase

2

0

High-throughput

0.547

High

525513

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.547

High

657353

ABCD3
ATP-binding cassette sub-family D member 3

2

0

High-throughput

0.547

High

736480

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.547

High

842512

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.547

High

929207

RS21
Small ribosomal subunit protein eS21

2

0

High-throughput

0.547

High

989806

RL18
Large ribosomal subunit protein eL18

2

0

High-throughput

0.547

High

1068471

FA83H
Protein FAM83H

2

0

High-throughput

0.547

High

1068475

MEPCE
7SK snRNA methylphosphate capping enzyme

2

0

High-throughput

0.547

High

1068481

MTMRE
Myotubularin-related protein 14

2

0

High-throughput

0.547

High

1068484

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

2

0

High-throughput

0.547

High

1068487

RENT1
Regulator of nonsense transcripts 1

2

0

High-throughput

0.547

High

1068492

CAVN3
Caveolae-associated protein 3

2

0

High-throughput

0.547

High

1068502

TMM43
Transmembrane protein 43

2

0

High-throughput

0.547

High

1068517

LTOR3
Ragulator complex protein LAMTOR3

2

0

High-throughput

0.547

High

208140

SPY2
Protein sprouty homolog 2

1

0

Small-scale

0.537

High

679048

HXD11
Homeobox protein Hox-D11

1

5

High-throughput

0.536

High

1068468

GRAP1
GRIP1-associated protein 1

1

9

High-throughput

0.536

High

1068476

K1C27
Keratin, type I cytoskeletal 27

1

4

High-throughput

0.536

High

1068485

LPIN2
Phosphatidate phosphatase LPIN2

1

1

High-throughput

0.536

High

131779

LAD1
Ladinin-1

2

1

High-throughput

0.521

High

150038

IF1AY
Eukaryotic translation initiation factor 1A, Y-chromosomal

2

1

High-throughput

0.521

High

327178

TXD12
Thioredoxin domain-containing protein 12

2

1

High-throughput

0.521

High

454026

COX6C
Cytochrome c oxidase subunit 6C

2

1

High-throughput

0.521

High

838414

CRIP1
Cysteine-rich protein 1

2

12

High-throughput

0.521

High

1068466

DREB
Drebrin

2

6

High-throughput

0.521

High

1068494

EFHD2
EF-hand domain-containing protein D2

2

14

High-throughput

0.521

High

1068478

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1068510

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

386767

P53
Cellular tumor antigen p53

1

4

Small-scale

0.501

High

403647

AP2A
Transcription factor AP-2-alpha

1

1

Small-scale

0.501

High

862225

ARFP1
Arfaptin-1

1

8

Small-scale

0.501

High

897249

CSN2
COP9 signalosome complex subunit 2

1

2

Small-scale

0.501

High

1068488

CSN5
COP9 signalosome complex subunit 5

1

1

Small-scale

0.501

High

1068470

KLD10
Kelch domain-containing protein 10

1

6

High-throughput

0.489

High

165983

PER2
Period circadian protein homolog 2

1

8

Small-scale

0.479

High

237428

TLR5
Toll-like receptor 5

1

2

Small-scale

0.479

High

487450

ANDR
Androgen receptor

1

14

High-throughput

0.479

High

808623

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

847151

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

1

6

High-throughput

0.479

High

1068482

HDAC7
Histone deacetylase 7

1

17

Small-scale

0.479

High

1068489

BAD
Bcl2-associated agonist of cell death

1

4

Small-scale

0.479

High

1068505

GAN
Gigaxonin

1

2

High-throughput

0.479

High

378055

PRIO
Major prion protein

1

1

High-throughput

0.445

High

1068496

CK5P2
CDK5 regulatory subunit-associated protein 2

1

17

High-throughput

0.445

High

100780

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

157574

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.298

High

540735

CX6B1
Cytochrome c oxidase subunit 6B1

2

0

High-throughput

0.298

High

946878

RT22
Small ribosomal subunit protein mS22

2

0

High-throughput

0.298

High

1068467

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.298

High

1068498

POP1
Ribonucleases P/MRP protein subunit POP1

2

0

High-throughput

0.298

High

1068501

TRIR
Telomerase RNA component interacting RNase

2

0

High-throughput

0.298

High

1068503

MMTA2
Multiple myeloma tumor-associated protein 2

2

0

High-throughput

0.298

High

1068511

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

High-throughput

0.298

High

1068512

GAR1
H/ACA ribonucleoprotein complex subunit 1

2

0

High-throughput

0.298

High

1068518

MRT4
mRNA turnover protein 4 homolog

2

0

High-throughput

0.298

High


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Last updated: 15 Jul 2024