Protein: VRK3
Serine/threonine-protein kinase VRK3 (EC 2.7.11.22) (Vaccinia-related kinase 3)

Gene: VRK3
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q8IV63

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1217334

ZN524
Zinc finger protein 524

3

1

High-throughput

0.861

High

970891

SP4
Transcription factor Sp4

2

2

High-throughput

0.811

High

969096

KPCE
Protein kinase C epsilon type

1

15

High-throughput

0.691

High

1036711

SQSTM
Sequestosome-1

1

3

High-throughput

0.691

High

1057966

RRP5
Protein RRP5 homolog

1

4

High-throughput

0.691

High

1217357

NR2E1
Nuclear receptor subfamily 2 group E member 1

3

15

High-throughput

0.667

High

861832

PLK1
Serine/threonine-protein kinase PLK1

1

17

High-throughput

0.656

High

931717

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.656

High

1217344

SCRT1
Transcriptional repressor scratch 1

1

3

High-throughput

0.618

High

1217355

ANR50
Ankyrin repeat domain-containing protein 50

1

1

High-throughput

0.618

High

202215

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

2

High-throughput

0.618

High

374496

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

432031

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

432798

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.618

High

453457

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

11

High-throughput

0.618

High

538575

CCNB1
G2/mitotic-specific cyclin-B1

1

6

High-throughput

0.618

High

582375

NUCL
Nucleolin

1

1

High-throughput

0.618

High

609946

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

9

High-throughput

0.618

High

852982

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

2

High-throughput

0.618

High

919151

RAN
GTP-binding nuclear protein Ran

1

10

Small-scale

0.618

High

933015

ACTS
Actin, alpha skeletal muscle

1

8

High-throughput

0.618

High

1077902

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

17

High-throughput

0.618

High

1082860

CDC37
Hsp90 co-chaperone Cdc37

1

4

High-throughput

0.618

High

1201091

THOC4
THO complex subunit 4

1

2

High-throughput

0.618

High

1217322

VRK3
Serine/threonine-protein kinase VRK3

1

16

High-throughput

0.618

High

1217323

CMYA5
Cardiomyopathy-associated protein 5

1

18

High-throughput

0.618

High

1217332

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

16

High-throughput

0.618

High

1217335

LMTK3
Serine/threonine-protein kinase LMTK3

1

20

High-throughput

0.618

High

1217348

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1217350

TLR9
Toll-like receptor 9

1

1

High-throughput

0.618

High

1217353

UBQL2
Ubiquilin-2

1

7

High-throughput

0.618

High

387045

P53
Cellular tumor antigen p53

2

7

High-throughput

0.584

High

917547

H4
Histone H4

2

5

High-throughput

0.584

High

952454

H33
Histone H3.3

2

10

High-throughput

0.584

High

369949

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

1217325

TXND5
Thioredoxin domain-containing protein 5

2

3

High-throughput

0.558

High

898152

MAX
Protein max

1

10

High-throughput

0.554

High

515603

SRF
Serum response factor

1

2

High-throughput

0.536

High

536536

IRF2
Interferon regulatory factor 2

1

2

High-throughput

0.536

High

564961

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

857492

HMGA2
High mobility group protein HMGI-C

1

3

High-throughput

0.536

High

898960

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.536

High

980994

EMX2
Homeobox protein EMX2

1

1

High-throughput

0.536

High

1217330

EZH1
Histone-lysine N-methyltransferase EZH1

1

3

High-throughput

0.536

High

1217347

FOXP1
Forkhead box protein P1

1

6

High-throughput

0.536

High

1217349

TF7L2
Transcription factor 7-like 2

1

8

High-throughput

0.536

High

1217354

FOXD3
Forkhead box protein D3

1

6

High-throughput

0.536

High

307262

RCBT2
RCC1 and BTB domain-containing protein 2

1

5

High-throughput

0.515

High

1152308

TWF2
Twinfilin-2

1

2

High-throughput

0.515

High

157054

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.513

High

1217329

GEMI6
Gem-associated protein 6

1

0

High-throughput

0.513

High

1217346

PIP30
PSME3-interacting protein

1

0

High-throughput

0.513

High

175024

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.501

High

1217356

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

1174051

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

2

High-throughput

0.489

High

1217337

SORT
Sortilin

1

1

High-throughput

0.489

High

195480

DHX15
ATP-dependent RNA helicase DHX15

1

3

High-throughput

0.479

High

268492

BAF
Barrier-to-autointegration factor

1

3

High-throughput

0.479

High

400594

RLA2
Large ribosomal subunit protein P2

1

3

High-throughput

0.479

High

418437

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

428289

TBB5
Tubulin beta chain

1

14

High-throughput

0.479

High

443632

VIME
Vimentin

1

8

High-throughput

0.479

High

444197

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.479

High

455624

PARP1
Poly [ADP-ribose] polymerase 1

1

9

High-throughput

0.479

High

489139

H14
Histone H1.4

1

6

High-throughput

0.479

High

499896

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

504353

HSP7C
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.479

High

518410

ADT3
ADP/ATP translocase 3

1

9

High-throughput

0.479

High

523864

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.479

High

524976

XRCC5
X-ray repair cross-complementing protein 5

1

4

High-throughput

0.479

High

531204

EF2
Elongation factor 2

1

3

High-throughput

0.479

High

564114

HSP76
Heat shock 70 kDa protein 6

1

12

High-throughput

0.479

High

569859

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

573352

TCPA
T-complex protein 1 subunit alpha

1

6

High-throughput

0.479

High

578015

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.479

High

618124

COF1
Cofilin-1

1

2

High-throughput

0.479

High

638164

PSA4
Proteasome subunit alpha type-4

1

3

High-throughput

0.479

High

642438

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

644088

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.479

High

647082

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

671278

RL12
Large ribosomal subunit protein uL11

1

1

High-throughput

0.479

High

714293

HSP74
Heat shock 70 kDa protein 4

1

15

High-throughput

0.479

High

717201

CTNB1
Catenin beta-1

1

9

High-throughput

0.479

High

799120

NKX21
Homeobox protein Nkx-2.1

1

2

High-throughput

0.479

High

806348

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.479

High

818219

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

821296

TCPE
T-complex protein 1 subunit epsilon

1

8

High-throughput

0.479

High

824169

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

10

High-throughput

0.479

High

829123

PCY1A
Choline-phosphate cytidylyltransferase A

1

2

High-throughput

0.479

High

838960

EMD
Emerin

1

3

High-throughput

0.479

High

842562

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.479

High

867447

ICLN
Methylosome subunit pICln

1

1

High-throughput

0.479

High

893081

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

898379

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

904026

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

6

High-throughput

0.479

High

905675

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

906006

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

15

High-throughput

0.479

High

906522

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

15

High-throughput

0.479

High

907709

RS15A
Small ribosomal subunit protein uS8

1

2

High-throughput

0.479

High

910488

RS14
Small ribosomal subunit protein uS11

1

1

High-throughput

0.479

High

910877

RS18
Small ribosomal subunit protein uS13

1

2

High-throughput

0.479

High

916260

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

920245

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

922619

RL10A
Large ribosomal subunit protein uL1

1

4

High-throughput

0.479

High

923101

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

933879

TBB4B
Tubulin beta-4B chain

1

14

High-throughput

0.479

High

943332

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.479

High

962196

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

4

High-throughput

0.479

High

970811

DSG1
Desmoglein-1

1

6

High-throughput

0.479

High

971498

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.479

High

989344

PRDX1
Peroxiredoxin-1

1

2

High-throughput

0.479

High

1057227

KCTD2
BTB/POZ domain-containing protein KCTD2

1

8

High-throughput

0.479

High

1087241

H2B2E
Histone H2B type 2-E

1

18

High-throughput

0.479

High

1217324

KCD17
BTB/POZ domain-containing protein KCTD17

1

10

High-throughput

0.479

High

1217327

BICD2
Protein bicaudal D homolog 2

1

14

High-throughput

0.479

High

1217331

JARD2
Protein Jumonji

1

2

High-throughput

0.479

High

1217338

ATX2
Ataxin-2

1

2

High-throughput

0.479

High

1217340

H2A1J
Histone H2A type 1-J

1

4

High-throughput

0.479

High

1217341

H2B1M
Histone H2B type 1-M

1

18

High-throughput

0.479

High

1217342

TBA1C
Tubulin alpha-1C chain

1

20

High-throughput

0.479

High

1217345

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

1

11

High-throughput

0.479

High

1217351

BCLF1
Bcl-2-associated transcription factor 1

1

3

High-throughput

0.479

High

1217352

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

4

High-throughput

0.479

High

1217358

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

400351

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.458

High

591010

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

807431

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

912328

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

927981

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

0

High-throughput

0.458

High

1174208

MOB2
MOB kinase activator 2

1

0

High-throughput

0.458

High

1217326

DC2L1
Cytoplasmic dynein 2 light intermediate chain 1

1

0

High-throughput

0.458

High

1217333

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1217336

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.458

High

1217343

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

1

0

High-throughput

0.458

High

1217359

SPIN1
Spindlin-1

1

0

High-throughput

0.458

High

402219

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

1217339

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.438

High

100925

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1192477

CNTRL
Centriolin

1

8

High-throughput

0.437

High

1217328

RBCC1
RB1-inducible coiled-coil protein 1

1

16

High-throughput

0.437

High

159660

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

456172

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

1161467

CP087
UPF0547 protein C16orf87

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024