Protein: SETD7
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9)

Gene: SETD7
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q8WTS6

Gene Ontology (top 5):
GO:0002039 - p53 binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935022

H31
Histone H3.1

5

4

Small-scale

0.937

High

917644

H4
Histone H4

2

1

Small-scale

0.778

High

1086237

H31T
Histone H3.1t

2

4

Small-scale

0.778

High

1259473

SETD7
Histone-lysine N-methyltransferase SETD7

2

8

Small-scale

0.778

High

387179

P53
Cellular tumor antigen p53

7

3

Small-scale

0.755

High

1259477

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

2

Small-scale

0.747

High

1087064

H2A2C
Histone H2A type 2-C

1

2

High-throughput

0.691

High

585022

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.687

High

978821

TF65
Transcription factor p65

4

0

Small-scale

0.686

High

641251

DNMT1
DNA

2

1

Small-scale

0.674

High

952491

H33
Histone H3.3

1

4

Small-scale

0.647

High

963649

E2F1
Transcription factor E2F1

3

0

Small-scale

0.627

High

1146660

A16L1
Autophagy-related protein 16-1

1

0

Small-scale

0.625

High

1021627

TAF10
Transcription initiation factor TFIID subunit 10

2

0

Small-scale

0.622

High

370079

ESR1
Estrogen receptor

2

5

Small-scale

0.602

High

1259474

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

Small-scale

0.589

High

1259476

NR1H4
Bile acid receptor

1

5

Small-scale

0.586

High

1259478

RIOK1
Serine/threonine-protein kinase RIO1

1

1

Small-scale

0.578

High

1074868

TAF7
Transcription initiation factor TFIID subunit 7

2

0

Small-scale

0.569

High

546013

MYOD1
Myoblast determination protein 1

1

1

Small-scale

0.561

High

818290

SOX2
Transcription factor SOX-2

1

4

Small-scale

0.561

High

1259475

OTUB1
Ubiquitin thioesterase OTUB1

1

1

Small-scale

0.561

High

776759

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.554

High

1259482

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.549

High

1259483

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

0

Small-scale

0.537

High

495577

THIO
Thioredoxin

1

1

High-throughput

0.536

High

570560

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

2

High-throughput

0.536

High

1016218

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.536

High

1259484

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

High-throughput

0.536

High

273462

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.513

High

396266

ARGI1
Arginase-1

1

0

High-throughput

0.513

High

427626

ANXA2
Annexin A2

1

0

High-throughput

0.513

High

559856

H12
Histone H1.2

1

0

High-throughput

0.513

High

683116

CASPE
Caspase-14

1

0

High-throughput

0.513

High

1046235

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

161414

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

5

Small-scale

0.501

High

167377

SMAD7
Mothers against decapentaplegic homolog 7

1

2

Small-scale

0.501

High

175066

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

204199

KLF4
Krueppel-like factor 4

1

4

Small-scale

0.501

High

476100

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

159601

ML12B
Myosin regulatory light chain 12B

1

9

High-throughput

0.489

High

891570

MYL6
Myosin light polypeptide 6

1

6

High-throughput

0.489

High

622814

COT2
COUP transcription factor 2

1

2

High-throughput

0.481

High

414338

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.480

High

962883

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

228162

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

487611

ANDR
Androgen receptor

1

4

Small-scale

0.479

High

1169170

RN111
E3 ubiquitin-protein ligase Arkadia

1

2

Small-scale

0.479

High

1237968

ZFP41
Zinc finger protein 41 homolog

1

10

High-throughput

0.479

High

1259479

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

5

Small-scale

0.479

High

1259480

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

Small-scale

0.479

High

1259481

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

299429

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

589895

TBP
TATA-box-binding protein

1

0

Small-scale

0.458

High

836255

TAF6
Transcription initiation factor TFIID subunit 6

1

0

Small-scale

0.458

High

847029

SMCA4
Transcription activator BRG1

1

0

Small-scale

0.458

High

1085614

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

0.458

High

380216

A1BG
Alpha-1B-glycoprotein

1

1

High-throughput

0.439

High

517382

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

674866

AGTR1
Type-1 angiotensin II receptor

1

3

High-throughput

0.437

High

686710

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.437

High

997196

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

4

High-throughput

0.437

High

1131781

CE170
Centrosomal protein of 170 kDa

1

2

High-throughput

0.437

High

1132640

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.426

High

814828

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.279

Low

946576

DCD
Dermcidin

1

0

High-throughput

0.279

Low

993985

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.279

Low

498316

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

0

High-throughput

0.251

Low

1145565

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.251

Low

100999

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

946417

EREP3
Protein ENTREP3

1

0

High-throughput

0.249

Low

378112

PRIO
Major prion protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024