Protein: MUC1
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]

Gene: MUC1
Organism: Homo sapiens
Interactions: 169
UniProt ID: P15941

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002039 - p53 binding
GO:0003712 - transcription coregulator activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554276

CTNB1
Catenin beta-1

9

4

Small-scale

0.757

High

337875

EGFR
Epidermal growth factor receptor

8

19

Small-scale

0.756

High

522749

SRC
Proto-oncogene tyrosine-protein kinase Src

3

9

Small-scale

0.692

High

554351

VPP1
V-type proton ATPase 116 kDa subunit a 1

3

2

High-throughput

0.667

High

554385

VPP2
V-type proton ATPase 116 kDa subunit a 2

3

2

High-throughput

0.667

High

554284

GSK3B
Glycogen synthase kinase-3 beta

2

7

Small-scale

0.664

High

554292

GRB2
Growth factor receptor-bound protein 2

2

14

Small-scale

0.640

High

554358

MYADM
Myeloid-associated differentiation marker

3

0

High-throughput

0.636

High

337335

ABL1
Tyrosine-protein kinase ABL1

1

9

Small-scale

0.620

High

154304

TR10B
Tumor necrosis factor receptor superfamily member 10B

2

3

High-throughput

0.606

High

306753

VAMP5
Vesicle-associated membrane protein 5

2

4

High-throughput

0.606

High

394059

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.606

High

416131

CO2
Complement C2

2

2

High-throughput

0.606

High

422651

TRBM
Thrombomodulin

2

14

High-throughput

0.606

High

506096

ITAM
Integrin alpha-M

2

1

High-throughput

0.606

High

554264

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.606

High

554271

AQP1
Aquaporin-1

2

2

High-throughput

0.606

High

554272

MIP
Lens fiber major intrinsic protein

2

2

High-throughput

0.606

High

554274

CD68
Macrosialin

2

1

High-throughput

0.606

High

554281

AQP2
Aquaporin-2

2

2

High-throughput

0.606

High

554287

CLD6
Claudin-6

2

2

High-throughput

0.606

High

554294

CP4F2
Cytochrome P450 4F2

2

2

High-throughput

0.606

High

554304

MALL
MAL-like protein

2

1

High-throughput

0.606

High

554309

ADIPO
Adiponectin

2

3

High-throughput

0.606

High

554327

ANR46
Ankyrin repeat domain-containing protein 46

2

10

High-throughput

0.606

High

554328

ZDH21
Palmitoyltransferase ZDHHC21

2

2

High-throughput

0.606

High

554337

CLD19
Claudin-19

2

2

High-throughput

0.606

High

554343

O10AG
Olfactory receptor 10AG1

2

1

High-throughput

0.606

High

554346

BT2A2
Butyrophilin subfamily 2 member A2

2

3

High-throughput

0.606

High

554347

AQP3
Aquaporin-3

2

2

High-throughput

0.606

High

554350

NINJ1
Ninjurin-1

2

1

High-throughput

0.606

High

554352

MAL2
Protein MAL2

2

1

High-throughput

0.606

High

554356

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

1

High-throughput

0.606

High

554376

NINJ2
Ninjurin-2

2

1

High-throughput

0.606

High

383583

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

19

Small-scale

0.584

High

554263

LEG3
Galectin-3

2

3

Small-scale

0.584

High

554300

SOS1
Son of sevenless homolog 1

2

2

Small-scale

0.584

High

70796

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.580

High

146947

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.580

High

225273

AGRB3
Adhesion G protein-coupled receptor B3

2

0

High-throughput

0.580

High

260257

ENTP3
Ectonucleoside triphosphate diphosphohydrolase 3

2

0

High-throughput

0.580

High

352374

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.580

High

361561

APOA2
Apolipoprotein A-II

2

0

High-throughput

0.580

High

514337

PSPC
Surfactant protein C

2

0

High-throughput

0.580

High

554261

TMM11
Transmembrane protein 11, mitochondrial

2

0

High-throughput

0.580

High

554280

GDNF
Glial cell line-derived neurotrophic factor

2

0

High-throughput

0.580

High

554286

EMP3
Epithelial membrane protein 3

2

0

High-throughput

0.580

High

554289

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.580

High

554295

RHD
Blood group Rh(D) polypeptide

2

0

High-throughput

0.580

High

554298

CCG1
Voltage-dependent calcium channel gamma-1 subunit

2

0

High-throughput

0.580

High

554299

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.580

High

554301

CD47
Leukocyte surface antigen CD47

2

0

High-throughput

0.580

High

554311

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

554317

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.580

High

554319

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

554324

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

554325

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.580

High

554326

PAQR6
Membrane progestin receptor delta

2

0

High-throughput

0.580

High

554329

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

554331

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

554340

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.580

High

554344

CLDN2
Claudin domain-containing protein 2

2

0

High-throughput

0.580

High

554345

SCAM5
Secretory carrier-associated membrane protein 5

2

0

High-throughput

0.580

High

554359

NEUR1
Sialidase-1

2

0

High-throughput

0.580

High

554364

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

554375

TECR
Very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.580

High

554378

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

0

High-throughput

0.580

High

554383

TMM98
Transmembrane protein 98

2

0

High-throughput

0.580

High

554387

SELK
Selenoprotein K

2

0

High-throughput

0.580

High

433560

LYN
Tyrosine-protein kinase Lyn

1

9

Small-scale

0.578

High

554279

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.578

High

554297

KPCD
Protein kinase C delta type

1

1

Small-scale

0.578

High

239044

CTND1
Catenin delta-1

1

8

Small-scale

0.561

High

368927

ESR1
Estrogen receptor

1

20

Small-scale

0.561

High

386039

P53
Cellular tumor antigen p53

1

7

Small-scale

0.561

High

411582

LCK
Tyrosine-protein kinase Lck

1

9

Small-scale

0.561

High

431504

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.561

High

554262

CEBPB
CCAAT/enhancer-binding protein beta

1

16

Small-scale

0.561

High

554275

HSP74
Heat shock 70 kDa protein 4

1

8

Small-scale

0.561

High

554283

ZAP70
Tyrosine-protein kinase ZAP-70

1

12

Small-scale

0.561

High

554305

ATM
Serine-protein kinase ATM

1

5

Small-scale

0.561

High

554308

TWST1
Twist-related protein 1

1

3

Small-scale

0.561

High

554273

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

2

4

High-throughput

0.553

High

554332

TM86A
Lysoplasmalogenase TMEM86A

2

1

High-throughput

0.553

High

554336

TM86B
Lysoplasmalogenase TMEM86B

2

1

High-throughput

0.553

High

554338

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.553

High

554349

B2CL2
Bcl-2-like protein 2

2

2

High-throughput

0.553

High

554353

S35B4
Nucleotide sugar transporter SLC35B4

2

1

High-throughput

0.553

High

554379

TM14C
Transmembrane protein 14C

2

1

High-throughput

0.553

High

554388

TM14A
Transmembrane protein 14A

2

1

High-throughput

0.553

High

554290

ACTA
Actin, aortic smooth muscle

1

14

High-throughput

0.536

High

554293

VAMP2
Vesicle-associated membrane protein 2

1

4

High-throughput

0.536

High

554315

ACTBL
Beta-actin-like protein 2

1

14

High-throughput

0.536

High

554341

AT11C
Phospholipid-transporting ATPase IG

1

1

High-throughput

0.536

High

401362

JUN
Transcription factor Jun

1

10

Small-scale

0.515

High

554259

MUC1
Mucin-1

1

17

Small-scale

0.515

High

554282

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

554322

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.513

High

554278

NUP62
Nuclear pore glycoprotein p62

1

17

Small-scale

0.512

High

554260

H2AX
Histone H2AX

1

9

Small-scale

0.501

High

554277

BMI1
Polycomb complex protein BMI-1

1

7

Small-scale

0.501

High

554310

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

Small-scale

0.501

High

554333

GALT4
Polypeptide N-acetylgalactosaminyltransferase 4

1

1

Small-scale

0.501

High

495894

PPGB
Lysosomal protective protein

1

1

High-throughput

0.481

High

554268

CO8A2
Collagen alpha-2(VIII) chain

1

5

High-throughput

0.481

High

554296

PLP2
Proteolipid protein 2

1

1

High-throughput

0.481

High

127176

IPO5
Importin-5

1

1

Small-scale

0.479

High

158388

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

Small-scale

0.479

High

441420

MET
Hepatocyte growth factor receptor

1

9

Small-scale

0.479

High

542170

PLAK
Junction plakoglobin

1

5

Small-scale

0.479

High

554265

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

Small-scale

0.479

High

554266

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

19

Small-scale

0.479

High

554267

APC
Adenomatous polyposis coli protein

1

16

Small-scale

0.479

High

554269

U2AF2
Splicing factor U2AF 65 kDa subunit

1

8

Small-scale

0.479

High

554303

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

554307

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.479

High

554312

HIF1A
Hypoxia-inducible factor 1-alpha

1

5

Small-scale

0.479

High

554348

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

554367

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

12

Small-scale

0.479

High

554389

NEMO
NF-kappa-B essential modulator

1

4

Small-scale

0.479

High

554302

Q08AM2
ADAM33 protein

1

3

High-throughput

0.470

High

554313

Q4VAQ0
COL8A2 protein

1

5

High-throughput

0.470

High

554316

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

173338

S22A1
Solute carrier family 22 member 1

1

0

Small-scale

0.460

High

554321

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.460

High

554368

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

554380

LPAR3
Lysophosphatidic acid receptor 3

1

0

High-throughput

0.460

High

554291

RL11
Large ribosomal subunit protein uL5

1

0

Small-scale

0.458

High

554330

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

1

Small-scale

0.457

High

263161

SC22B
Vesicle-trafficking protein SEC22b

1

1

High-throughput

0.439

High

554365

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

3

High-throughput

0.439

High

554373

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

1

High-throughput

0.439

High

355130

HBD
Hemoglobin subunit delta

1

2

High-throughput

0.437

High

49297

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

196728

CYB5B
Cytochrome b5 type B

2

0

High-throughput

0.316

High

239247

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.316

High

306385

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.316

High

554270

PPLA
Cardiac phospholamban

2

0

High-throughput

0.316

High

554285

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

554288

EP3B
Epididymal secretory protein E3-beta

2

0

High-throughput

0.316

High

554306

TM187
Transmembrane protein 187

2

0

High-throughput

0.316

High

554314

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

554318

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

554323

S35E4
Solute carrier family 35 member E4

2

0

High-throughput

0.316

High

554335

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

0

High-throughput

0.316

High

554339

SERP2
Stress-associated endoplasmic reticulum protein 2

2

0

High-throughput

0.316

High

554342

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

554354

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

2

0

High-throughput

0.316

High

554360

VKOR1
Vitamin K epoxide reductase complex subunit 1

2

0

High-throughput

0.316

High

554361

TM121
Transmembrane protein 121

2

0

High-throughput

0.316

High

554362

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

554363

EMC6
ER membrane protein complex subunit 6

2

0

High-throughput

0.316

High

554366

TM6S2
Transmembrane 6 superfamily member 2

2

0

High-throughput

0.316

High

554369

ARV1
Protein ARV1

2

0

High-throughput

0.316

High

554370

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

2

0

High-throughput

0.316

High

554371

GP108
Protein GPR108

2

0

High-throughput

0.316

High

554372

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.316

High

554374

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.316

High

554377

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

554382

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.316

High

554384

GOT1B
Vesicle transport protein GOT1B

2

0

High-throughput

0.316

High

554386

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

554320

MKS3
Meckelin

1

0

High-throughput

0.279

Low

554334

TM199
Transmembrane protein 199

1

0

High-throughput

0.279

Low

554357

CC115
Coiled-coil domain-containing protein 115

1

0

High-throughput

0.279

Low

554381

TM59L
Transmembrane protein 59-like

1

0

High-throughput

0.279

Low

58275

TM218
Transmembrane protein 218

1

0

High-throughput

0.251

Low

554355

YIPF6
Protein YIPF6

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024