Protein: SPK1
Guanine nucleotide exchange factor SPIKE 1

Gene: SPK1
Organism: Arabidopsis thaliana
Interactions: 23
UniProt ID: Q8SAB7

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005789 - endoplasmic reticulum membrane
GO:0007264 - small GTPase-mediated signal transduction
GO:0008064 - regulation of actin polymerization or depolymerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1182502

RAC4
Rac-like GTP-binding protein ARAC4

2

20

Small-scale

0.831

High

1342970

RAC6
Rac-like GTP-binding protein ARAC6

2

20

Small-scale

0.781

High

1342965

SPK1
Guanine nucleotide exchange factor SPIKE 1

1

11

Small-scale

0.740

High

308285

RAC10
Rac-like GTP-binding protein ARAC10

1

20

Small-scale

0.656

High

1342972

RAC9
Rac-like GTP-binding protein ARAC9

1

20

Small-scale

0.656

High

1182471

RAC1
Rac-like GTP-binding protein ARAC1

1

20

Small-scale

0.647

High

1182532

RAC5
Rac-like GTP-binding protein ARAC5

1

20

Small-scale

0.647

High

1342971

RAC8
Rac-like GTP-binding protein ARAC8

1

20

Small-scale

0.647

High

884892

P2C56
Protein phosphatase 2C 56

1

1

Small-scale

0.527

High

1220925

SCAR2
Protein SCAR2

1

3

Small-scale

0.523

High

1209901

NCKP1
Protein NAP1

1

0

Small-scale

0.493

High

1220922

SCAR4
Protein SCAR4

1

3

Small-scale

0.464

High

1231031

SCAR1
Protein SCAR1

1

3

Small-scale

0.464

High

1342967

SCAR3
Protein SCAR3

1

3

Small-scale

0.464

High

1342887

ABIL1
Protein ABIL1

1

3

Small-scale

0.462

High

49255

ABI4
Ethylene-responsive transcription factor ABI4

1

0

Small-scale

0.460

High

1031159

ABI3
B3 domain-containing transcription factor ABI3

1

0

Small-scale

0.460

High

147016

P2C77
Protein phosphatase 2C 77

1

1

Small-scale

0.439

High

1236653

ABIL3
Protein ABIL3

1

3

Small-scale

0.417

High

1342966

ABIL4
Protein ABIL4

1

3

Small-scale

0.417

High

1342969

ABIL2
Protein ABIL2

1

3

Small-scale

0.417

High

1342968

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025