HitPredict

Interactor 1: KI20A (O95235)
Kinesin-like protein KIF20A (GG10_2) (Mitotic kinesin-like protein 2) (MKlp2) (Rab6-interacting kinesin-like protein) (Rabkinesin-6)
Gene: KIF20A

Interactor 2: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25476789, 26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 4834
+	Mm
		1118135 KINH_MOUSE (58-252): 1.37e-31: 135: 24.24		HERC2_MOUSE (1-4834): 0: 6208: 95.51
+	Mm
		659995 KIF5C_MOUSE (58-265): 2.62e-30: 131: 23.22		HERC2_MOUSE (1-4834): 0: 6208: 95.51
+	Mm
		1118145 KIF11_MOUSE (299-677): 8.06e-30: 129: 30.51		HERC2_MOUSE (1-4834): 0: 6208: 95.51
+	Hs
		969812 KIF23_HUMAN (60-772): 3.56e-103: 344: 25.21		HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00
+	Hs
		308722 KI20A_HUMAN (1-890): 0: 562: 100.00		HERC3_HUMAN (310-574): 2.63e-42: 173: 16.94
+	Hs
		101676 KI20A_HUMAN (1-890): 0: 562: 100.00		F8VWT9_HUMAN (4338-4787): 2.28e-33: 145: 28.02
+	Hs
		1066555 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		NED4L_HUMAN (4321-4795): 3.82e-167: 547: 19.84
+	Hs
		166382 KIF3B_HUMAN (60-229): 2.75e-28: 124: 21.97		NED4L_HUMAN (4321-4795): 3.82e-167: 547: 19.84
+	Hs
		855737 KIF11_HUMAN (299-644): 1.1e-28: 125: 30.99		SMUF2_HUMAN (4316-4794): 1.68e-158: 513: 22.11
+	Hs
		308742 KI20A_HUMAN (1-890): 0: 562: 100.00		HERC1_HUMAN (2867-3016): 8.76e-11: 71.4: 12.34
+	Hs
		855740 KIF11_HUMAN (299-644): 1.1e-28: 125: 30.99		SMUF1_HUMAN (4321-4794): 2.56e-156: 507: 20.58
+	Hs
		1192210 KI13A_HUMAN (61-262): 6.34e-33: 140: 20.74		HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00
+	Hs
		702933 KINH_HUMAN (61-252): 1.28e-31: 135: 25.13		HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00
+	Mm
		659998 KIF5C_MOUSE (58-265): 2.62e-30: 131: 23.22		HUWE1_MOUSE (4365-4788): 3.47e-118: 426: 24.00
+	Mm
		1186494 KI21A_MOUSE (583-879): 5.13e-13: 75.6: 13.71		HUWE1_MOUSE (4365-4788): 3.47e-118: 426: 24.00
+	Hs
		970050 KIF23_HUMAN (60-772): 3.56e-103: 344: 25.21		HERC5_HUMAN (424-597): 6.72e-11: 71.2: 26.56
+	Hs
		231531 KIF1B_HUMAN (64-229): 1.47e-33: 142: 19.89		HERC1_HUMAN (2867-3016): 8.76e-11: 71.4: 12.34
+	Hs
		1066168 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		HERC1_HUMAN (2867-3016): 8.76e-11: 71.4: 12.34