Protein: TMOD3
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)

Gene: TMOD3
Organism: Homo sapiens
Interactions: 217
UniProt ID: Q9NYL9

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005523 - tropomyosin binding
GO:0005856 - cytoskeleton
GO:0005865 - striated muscle thin filament
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892073

ACTB
Actin, cytoplasmic 1

4

12

High-throughput

0.903

High

932411

ACTC
Actin, alpha cardiac muscle 1

3

10

High-throughput

0.867

High

414084

GELS
Gelsolin

2

11

High-throughput

0.811

High

1023245

FLII
Protein flightless-1 homolog

2

12

High-throughput

0.811

High

1348584

SCIN
Scinderin

2

11

High-throughput

0.811

High

313893

SVIL
Supervillin

2

11

High-throughput

0.726

High

474856

POTEI
POTE ankyrin domain family member I

2

11

High-throughput

0.726

High

915520

ACTA
Actin, aortic smooth muscle

2

11

High-throughput

0.726

High

1122520

ACTBL
Beta-actin-like protein 2

2

11

High-throughput

0.726

High

1343904

MYO5C
Unconventional myosin-Vc

3

6

High-throughput

0.675

High

1343708

ANLN
Anillin

3

2

High-throughput

0.656

High

894513

CDC42
Cell division control protein 42 homolog

3

9

High-throughput

0.641

High

257146

PHAR2
Phosphatase and actin regulator 2

2

2

High-throughput

0.628

High

526459

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

2

2

High-throughput

0.628

High

997254

SPIR1
Protein spire homolog 1

2

1

High-throughput

0.628

High

1103967

LRRF1
Leucine-rich repeat flightless-interacting protein 1

2

6

High-throughput

0.628

High

1152323

TWF2
Twinfilin-2

2

2

High-throughput

0.628

High

1237891

ENAH
Protein enabled homolog

2

2

High-throughput

0.628

High

1262684

SPIR2
Protein spire homolog 2

2

1

High-throughput

0.628

High

1264535

SSH1
Protein phosphatase Slingshot homolog 1

2

3

High-throughput

0.628

High

1348577

MYO5B
Unconventional myosin-Vb

2

7

High-throughput

0.628

High

1348581

MYO5A
Unconventional myosin-Va

2

7

High-throughput

0.628

High

1100162

INF2
Inverted formin-2

2

0

High-throughput

0.602

High

529807

CFTR
Cystic fibrosis transmembrane conductance regulator

3

2

High-throughput

0.587

High

197097

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

2

High-throughput

0.574

High

232726

TBCD4
TBC1 domain family member 4

2

1

High-throughput

0.574

High

612064

HEMH
Ferrochelatase, mitochondrial

2

1

High-throughput

0.574

High

773146

PBX2
Pre-B-cell leukemia transcription factor 2

2

3

High-throughput

0.574

High

862112

DAPK1
Death-associated protein kinase 1

2

4

High-throughput

0.574

High

1203061

LONP2
Lon protease homolog 2, peroxisomal

2

1

High-throughput

0.574

High

1294482

LRCH3
DISP complex protein LRCH3

2

3

High-throughput

0.574

High

1298532

DOCK7
Dedicator of cytokinesis protein 7

2

1

High-throughput

0.574

High

1333493

CSR2B
Cysteine-rich protein 2-binding protein

2

1

High-throughput

0.574

High

1348583

LRRF2
Leucine-rich repeat flightless-interacting protein 2

2

11

High-throughput

0.574

High

882608

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

4

High-throughput

0.571

High

117842

MYO1C
Unconventional myosin-Ic

1

12

High-throughput

0.536

High

297421

MYO1D
Unconventional myosin-Id

1

12

High-throughput

0.536

High

497687

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

725044

MYH9
Myosin-9

1

1

High-throughput

0.536

High

984668

CALD1
Caldesmon

1

15

High-throughput

0.536

High

1016524

TWF1
Twinfilin-1

1

2

High-throughput

0.536

High

1085082

DREB
Drebrin

1

2

High-throughput

0.536

High

1229800

ABRA
Actin-binding Rho-activating protein

1

2

High-throughput

0.536

High

1232634

SYNPO
Synaptopodin

1

1

High-throughput

0.536

High

1293062

MYO19
Unconventional myosin-XIX

1

8

High-throughput

0.536

High

1304251

PARK7
Parkinson disease protein 7

1

2

High-throughput

0.536

High

370580

ESR1
Estrogen receptor

2

9

Small-scale

0.533

High

398115

ISG15
Ubiquitin-like protein ISG15

2

3

High-throughput

0.533

High

508230

FGFR1
Fibroblast growth factor receptor 1

2

2

High-throughput

0.521

High

596437

RASA1
Ras GTPase-activating protein 1

2

4

High-throughput

0.521

High

1024840

DUS4
Dual specificity protein phosphatase 4

2

3

High-throughput

0.521

High

934521

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.520

High

154530

MEIS2
Homeobox protein Meis2

1

3

High-throughput

0.489

High

570601

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

1

High-throughput

0.489

High

598351

FLNA
Filamin-A

1

2

High-throughput

0.489

High

625616

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.489

High

686083

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.489

High

773093

PBX1
Pre-B-cell leukemia transcription factor 1

1

3

High-throughput

0.489

High

773212

PBX3
Pre-B-cell leukemia transcription factor 3

1

3

High-throughput

0.489

High

809456

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.489

High

813183

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.489

High

827286

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.489

High

906616

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

5

High-throughput

0.489

High

1039181

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.489

High

1255912

TBCK
TBC domain-containing protein kinase-like protein

1

2

High-throughput

0.489

High

1268101

MY18A
Unconventional myosin-XVIIIa

1

10

High-throughput

0.489

High

1348576

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.489

High

120675

RHOD
Rho-related GTP-binding protein RhoD

1

11

High-throughput

0.479

High

522227

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

717385

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

813792

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.479

High

901256

RND3
Rho-related GTP-binding protein RhoE

1

11

High-throughput

0.479

High

1042688

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1044203

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.479

High

1130664

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

Small-scale

0.479

High

1169501

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

10

High-throughput

0.479

High

1172014

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1296750

RHOV
Rho-related GTP-binding protein RhoV

1

10

High-throughput

0.479

High

1317630

RHBT2
Rho-related BTB domain-containing protein 2

1

12

High-throughput

0.479

High

1348574

HDAC6
Histone deacetylase 6

1

4

High-throughput

0.479

High

364456

TFR1
Transferrin receptor protein 1

1

2

High-throughput

0.470

High

1174156

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

2

High-throughput

0.470

High

1263919

CLC4D
C-type lectin domain family 4 member D

1

4

High-throughput

0.470

High

155700

TNF11
Tumor necrosis factor ligand superfamily member 11

1

1

High-throughput

0.464

High

1313936

DUS23
Dual specificity protein phosphatase 23

1

5

High-throughput

0.464

High

1326184

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

High-throughput

0.464

High

780216

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1253616

FBX25
F-box only protein 25

1

0

High-throughput

0.458

High

951403

RHOG
Rho-related GTP-binding protein RhoG

1

8

Small-scale

0.445

High

101234

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

178018

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.437

High

210331

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.437

High

302021

TRI37
E3 ubiquitin-protein ligase TRIM37

1

8

High-throughput

0.437

High

309113

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.437

High

345557

FOS
Protein c-Fos

1

2

High-throughput

0.437

High

348075

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.437

High

350613

RASK
GTPase KRas

1

9

High-throughput

0.437

High

352713

TNFA
Tumor necrosis factor

1

1

High-throughput

0.437

High

379952

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.437

High

442550

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.437

High

487799

ANDR
Androgen receptor

1

8

High-throughput

0.437

High

502615

BIP
Endoplasmic reticulum chaperone BiP

1

9

High-throughput

0.437

High

526079

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

547362

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.437

High

553904

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

611517

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

8

Small-scale

0.437

High

637583

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.437

High

652441

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

669023

PML
Protein PML

1

3

High-throughput

0.437

High

738086

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.437

High

786438

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

High-throughput

0.437

High

818536

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.437

High

841910

CDK9
Cyclin-dependent kinase 9

1

5

High-throughput

0.437

High

845290

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.437

High

846884

SMCA2
Probable global transcription activator SNF2L2

1

3

High-throughput

0.437

High

850214

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.437

High

851361

NEK2
Serine/threonine-protein kinase Nek2

1

4

Small-scale

0.437

High

870912

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.437

High

884604

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.437

High

914407

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.437

High

965865

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

970031

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.437

High

1016255

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.437

High

1024426

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.437

High

1026561

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

1046184

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.437

High

1054627

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

1064206

TNIP1
TNFAIP3-interacting protein 1

1

5

High-throughput

0.437

High

1066786

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.437

High

1080407

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

1085999

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.437

High

1119498

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

2

High-throughput

0.437

High

1162065

TRI65
E3 ubiquitin-protein ligase TRIM65

1

6

Small-scale

0.437

High

1166681

CLC9A
C-type lectin domain family 9 member A

1

6

Small-scale

0.437

High

1198202

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

1200702

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.437

High

1224543

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

2

Small-scale

0.437

High

1235423

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

1

High-throughput

0.437

High

1245271

TRI58
E3 ubiquitin-protein ligase TRIM58

1

5

Small-scale

0.437

High

1259416

DUS19
Dual specificity protein phosphatase 19

1

3

High-throughput

0.437

High

1261306

RN138
E3 ubiquitin-protein ligase RNF138

1

11

High-throughput

0.437

High

1261429

NUDC2
NudC domain-containing protein 2

1

2

High-throughput

0.437

High

1269778

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1281433

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.437

High

1286722

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

1292259

AURKB
Aurora kinase B

1

1

High-throughput

0.437

High

1306387

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

1

High-throughput

0.437

High

1330525

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.437

High

1331468

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1333767

ECT2
Protein ECT2

1

12

High-throughput

0.437

High

1348575

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

1348578

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.437

High

1348580

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

240214

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

718252

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.407

High

750906

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

924906

GRB2
Growth factor receptor-bound protein 2

1

7

High-throughput

0.407

High

1032652

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.407

High

1153413

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.407

High

202539

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.328

High

254832

COBL
Protein cordon-bleu

2

0

High-throughput

0.328

High

235116

DOK2
Docking protein 2

2

0

High-throughput

0.298

High

261148

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.298

High

296154

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.298

High

175404

PPM1D
Protein phosphatase 1D

1

0

High-throughput

0.279

Low

1086114

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

0

High-throughput

0.279

Low

1183245

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

1201236

PIM3
Serine/threonine-protein kinase pim-3

1

0

High-throughput

0.279

Low

1257341

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.279

Low

1303813

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.279

Low

1313294

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.279

Low

1344775

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.279

Low

1347248

FBX34
F-box only protein 34

1

0

High-throughput

0.279

Low

648910

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.269

Low

128320

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.249

Low

168061

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.249

Low

233659

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

261024

H2AY
Core histone macro-H2A.1

1

0

Small-scale

0.249

Low

456952

FURIN
Furin

1

0

High-throughput

0.249

Low

525664

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.249

Low

591119

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

610516

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.249

Low

673109

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.249

Low

721624

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

786163

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

808972

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.249

Low

909234

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

910095

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.249

Low

935309

H31
Histone H3.1

1

0

High-throughput

0.249

Low

992143

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.249

Low

1016884

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.249

Low

1030520

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.249

Low

1053672

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1061650

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1119643

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1126692

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1135397

ARM12
Armadillo repeat-containing protein 12

1

0

Small-scale

0.249

Low

1148823

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1163884

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1188953

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1256439

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1267196

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

1291123

CDCA5
Sororin

1

0

High-throughput

0.249

Low

1310330

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.249

Low

1319089

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low

1328270

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1335503

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

1345437

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low

1347146

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.249

Low

1348573

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

1348579

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.249

Low

1348582

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

968232

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.232

Low

1134781

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1137053

LIN9
Protein lin-9 homolog

1

0

Small-scale

0.232

Low

1304787

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.232

Low

1348325

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024