Protein: SQSTM
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)

Gene: SQSTM, Sqstm1
Organism: Mus musculus
Interactions: 96
UniProt ID: Q64337

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0000425 - pexophagy
GO:0000932 - P-body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926416

MK01
Mitogen-activated protein kinase 1

2

6

Small-scale

0.799

High

250798

ULK1
Serine/threonine-protein kinase ULK1

2

10

Small-scale

0.776

High

1145371

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

2

6

Small-scale

0.770

High

1145341

SQSTM
Sequestosome-1

2

12

Small-scale

0.755

High

1145358

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

6

14

Small-scale

0.734

High

476833

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

5

15

Small-scale

0.714

High

1144377

MK03
Mitogen-activated protein kinase 3

1

6

Small-scale

0.691

High

1145344

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

4

4

Small-scale

0.687

High

1145374

KEAP1
Kelch-like ECH-associated protein 1

3

4

Small-scale

0.681

High

956455

NBR1
Next to BRCA1 gene 1 protein

1

2

Small-scale

0.681

High

1112477

NTRK1
High affinity nerve growth factor receptor

3

11

Small-scale

0.662

High

936237

TRAF6
TNF receptor-associated factor 6

3

16

Small-scale

0.650

High

103064

G3X9H5
Huntingtin

3

3

Small-scale

0.640

High

661009

KPCD
Protein kinase C delta type

1

13

Small-scale

0.618

High

973811

KPCZ
Protein kinase C zeta type

1

13

Small-scale

0.618

High

1145353

TRIB3
Tribbles homolog 3

1

5

Small-scale

0.618

High

1142139

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

8

Small-scale

0.617

High

292701

CASP8
Caspase-8

2

4

Small-scale

0.584

High

437617

SODC
Superoxide dismutase [Cu-Zn]

2

1

Small-scale

0.584

High

1145348

A16L1
Autophagy-related protein 16-1

2

6

Small-scale

0.584

High

1145356

NLRP3
NACHT, LRR and PYD domains-containing protein 3

2

5

Small-scale

0.584

High

1145362

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

14

Small-scale

0.584

High

548985

TR30A
Tripartite motif-containing protein 30A

1

6

Small-scale

0.561

High

1145352

OPTN
Optineurin

1

8

Small-scale

0.550

High

885197

SESN2
Sestrin-2

1

2

Small-scale

0.536

High

620893

GRIA1
Glutamate receptor 1

1

4

Small-scale

0.515

High

659685

RXRA
Retinoic acid receptor RXR-alpha

1

8

Small-scale

0.515

High

816998

VDR
Vitamin D3 receptor

1

6

Small-scale

0.515

High

1145360

NRIF1
Neurotrophin receptor-interacting factor 1

1

2

Small-scale

0.515

High

792154

HD
Huntingtin

1

3

Small-scale

0.500

High

102616

TRI55
Tripartite motif-containing 55

1

14

Small-scale

0.479

High

356866

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

546304

NTRK2
BDNF/NT-3 growth factors receptor

1

10

Small-scale

0.479

High

580482

ANDR
Androgen receptor

1

11

Small-scale

0.479

High

589635

VIME
Vimentin

1

7

Small-scale

0.479

High

607561

MYD88
Myeloid differentiation primary response protein MyD88

1

2

Small-scale

0.479

High

613316

CXA1
Gap junction alpha-1 protein

1

3

Small-scale

0.479

High

618971

IRF8
Interferon regulatory factor 8

1

2

Small-scale

0.479

High

620969

GRIA2
Glutamate receptor 2

1

4

Small-scale

0.479

High

653440

PDIA3
Protein disulfide-isomerase A3

1

1

Small-scale

0.479

High

666792

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

2

Small-scale

0.479

High

685484

LA
Lupus La protein homolog

1

6

Small-scale

0.479

High

706097

MMP2
72 kDa type IV collagenase

1

3

Small-scale

0.479

High

724604

IRS1
Insulin receptor substrate 1

1

5

Small-scale

0.479

High

782855

MMP9
Matrix metalloproteinase-9

1

3

Small-scale

0.479

High

808360

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

Small-scale

0.479

High

910636

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

920907

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

5

Small-scale

0.479

High

935517

1433F
14-3-3 protein eta

1

10

Small-scale

0.479

High

936679

ELAV1
ELAV-like protein 1

1

5

Small-scale

0.479

High

956530

SNAI2
Zinc finger protein SNAI2

1

4

Small-scale

0.479

High

956941

SMN
Survival motor neuron protein

1

2

Small-scale

0.479

High

968962

SNAI1
Zinc finger protein SNAI1

1

5

Small-scale

0.479

High

978967

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

1103184

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

1

3

Small-scale

0.479

High

1112813

TAXB1
Tax1-binding protein 1 homolog

1

7

Small-scale

0.479

High

1141357

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

6

Small-scale

0.479

High

1141515

KLF2
Krueppel-like factor 2

1

4

Small-scale

0.479

High

1141525

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

9

Small-scale

0.479

High

1141981

KLF3
Krueppel-like factor 3

1

5

Small-scale

0.479

High

1145164

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

3

High-throughput

0.479

High

1145343

Q7TMG8
Glioblastoma amplified sequence

1

2

Small-scale

0.479

High

1145345

SAM50
Sorting and assembly machinery component 50 homolog

1

2

Small-scale

0.479

High

1145347

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

3

Small-scale

0.479

High

1145350

MIC60
MICOS complex subunit Mic60

1

5

Small-scale

0.479

High

1145357

S25A3
Solute carrier family 25 member 3

1

3

Small-scale

0.479

High

1145364

TM160
Transmembrane protein 160

1

1

Small-scale

0.479

High

1145365

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

1

Small-scale

0.479

High

1145367

CUL3
Cullin-3

1

6

Small-scale

0.479

High

1145368

LIMD1
LIM domain-containing protein 1

1

13

Small-scale

0.479

High

1145370

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

1

Small-scale

0.479

High

1145372

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

Small-scale

0.479

High

1145373

GRIA3
Glutamate receptor 3

1

4

Small-scale

0.470

High

888069

RUVB1
RuvB-like 1

1

0

Small-scale

0.458

High

956285

RS3A
Small ribosomal subunit protein eS1

1

0

Small-scale

0.458

High

994726

GATA4
Transcription factor GATA-4

1

0

Small-scale

0.458

High

1110743

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

1142264

TS101
Tumor susceptibility gene 101 protein

1

0

Small-scale

0.458

High

1145359

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

Small-scale

0.458

High

1145361

LTMD1
LETM1 domain-containing protein 1

1

0

Small-scale

0.458

High

1145363

TECR
Very-long-chain enoyl-CoA reductase

1

0

Small-scale

0.458

High

1145351

FTM
Protein fantom

1

2

High-throughput

0.445

High

1145354

RAB38
Ras-related protein Rab-38

1

4

High-throughput

0.445

High

292605

COR1A
Coronin-1A

1

3

High-throughput

0.437

High

506790

FINC
Fibronectin

1

5

Small-scale

0.437

High

907210

PRS8
26S proteasome regulatory subunit 8

1

10

Small-scale

0.437

High

966919

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

Small-scale

0.437

High

1145349

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

3

Small-scale

0.437

High

1145355

ANGL8
Angiopoietin-like protein 8

1

1

Small-scale

0.437

High

1145366

XPO7
Exportin-7

1

5

High-throughput

0.407

High

291587

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low

1143641

SSRD
Translocon-associated protein subunit delta

1

0

Small-scale

0.249

Low

1145342

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.249

Low

1145346

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.249

Low

1145369

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024