Protein: FAK1
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)

Gene: FAK1, Ptk2
Organism: Mus musculus
Interactions: 38
UniProt ID: P34152

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000226 - microtubule cytoskeleton organization
GO:0001525 - angiogenesis
GO:0001568 - blood vessel development
GO:0001570 - vasculogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710146

PAXI
Paxillin

6

20

Small-scale

0.928

High

403419

SRC
Proto-oncogene tyrosine-protein kinase Src

4

20

Small-scale

0.873

High

710139

BCAR1
Breast cancer anti-estrogen resistance protein 1

3

20

Small-scale

0.860

High

710142

EFS
Embryonal Fyn-associated substrate

2

20

Small-scale

0.767

High

710126

FYN
Tyrosine-protein kinase Fyn

2

20

Small-scale

0.743

High

710138

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.695

High

710137

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

20

High-throughput

0.691

High

710140

DLG4
Disks large homolog 4

1

20

High-throughput

0.691

High

710123

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.647

High

710132

GRB7
Growth factor receptor-bound protein 7

1

20

Small-scale

0.647

High

193375

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.618

High

514127

L1CAM
Neural cell adhesion molecule L1

1

8

Small-scale

0.618

High

643057

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

710124

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.618

High

710125

DYN2
Dynamin-2

1

17

Small-scale

0.618

High

710128

EPHB2
Ephrin type-B receptor 2

1

19

Small-scale

0.618

High

710135

EPS8
Epidermal growth factor receptor kinase substrate 8

1

20

Small-scale

0.618

High

710141

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

Small-scale

0.618

High

710152

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.618

High

710150

DLGP1
Disks large-associated protein 1

2

12

High-throughput

0.611

High

710127

TIA1
Cytotoxic granule associated RNA binding protein TIA1

2

4

Small-scale

0.584

High

710145

MEF2C
Myocyte-specific enhancer factor 2C

1

0

Small-scale

0.549

High

710143

HDAC4
Histone deacetylase 4

1

19

High-throughput

0.536

High

710134

GATA4
Transcription factor GATA-4

1

1

Small-scale

0.501

High

102833

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

489476

BCL2
Apoptosis regulator Bcl-2

1

3

Small-scale

0.479

High

607534

MYD88
Myeloid differentiation primary response protein MyD88

1

14

Small-scale

0.479

High

710129

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

11

High-throughput

0.479

High

710130

ELAV1
ELAV-like protein 1

1

6

Small-scale

0.479

High

710131

NRP1
Neuropilin-1

1

6

Small-scale

0.479

High

710133

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

12

Small-scale

0.479

High

710136

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

710144

WDTC1
WD and tetratricopeptide repeats protein 1

1

18

High-throughput

0.479

High

710147

WASL
Actin nucleation-promoting factor WASL

1

20

Small-scale

0.479

High

710148

ARP3
Actin-related protein 3

1

8

Small-scale

0.479

High

710149

LPXN
Leupaxin

1

20

Small-scale

0.479

High

710151

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

17

Small-scale

0.479

High


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Last updated: 15 Jul 2024