HitPredict - High confidence protein-protein interactions

Protein: PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17)

Gene: PDE10, PDE10A
Organism: Homo sapiens
Interactions: 5
UniProt ID: Q9Y233

Gene Ontology (top 5):
GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0004118 - 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005829 - cytosol
GO:0006198 - cAMP catabolic process

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
673981	RS12 Small ribosomal subunit protein eS12	3	0	High-throughput	0.613	High
106873	APRIO Alternative prion protein	1	2	High-throughput	0.437	High
1462412	WDR3 WD repeat-containing protein 3	1	4	High-throughput	0.417	High
866454	CASA1 Alpha-S1-casein [Cleaved into: Casoxin-D]	2	0	High-throughput	0.328	High
542290	TOP1 DNA topoisomerase 1	1	0	Small-scale	0.213	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025