Protein: KLF11
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)

Gene: KLF11
Organism: Homo sapiens
Interactions: 246
UniProt ID: O14901

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

157870

MK01
Mitogen-activated protein kinase 1

2

6

Small-scale

0.818

High

157869

MK03
Mitogen-activated protein kinase 3

2

6

High-throughput

0.737

High

158009

SIN3A
Paired amphipathic helix protein Sin3a

4

10

Small-scale

0.680

High

110695

H3BUJ7
E4F transcription factor 1

1

18

High-throughput

0.665

High

157839

ZBT14
Zinc finger and BTB domain-containing protein 14

1

19

High-throughput

0.665

High

157844

KS6A4
Ribosomal protein S6 kinase alpha-4

1

6

High-throughput

0.665

High

157880

KS6A3
Ribosomal protein S6 kinase alpha-3

1

6

High-throughput

0.665

High

157886

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.665

High

157901

KLF5
Krueppel-like factor 5

1

19

High-throughput

0.665

High

157912

KS6A2
Ribosomal protein S6 kinase alpha-2

1

6

High-throughput

0.665

High

157914

ZXDC
Zinc finger protein ZXDC

1

17

High-throughput

0.665

High

157966

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

20

High-throughput

0.665

High

158001

ZN333
Zinc finger protein 333

1

17

High-throughput

0.665

High

158027

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

1

7

High-throughput

0.665

High

158037

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

2

High-throughput

0.665

High

158041

STK36
Serine/threonine-protein kinase 36

1

3

High-throughput

0.665

High

158048

MS18A
Protein Mis18-alpha

1

1

High-throughput

0.665

High

158054

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.665

High

158058

ZN346
Zinc finger protein 346

1

2

High-throughput

0.665

High

157838

MS18B
Protein Mis18-beta

1

0

High-throughput

0.630

High

158010

CRBN
Protein cereblon

1

0

High-throughput

0.630

High

157834

KLF11
Krueppel-like factor 11

1

19

High-throughput

0.618

High

157864

EGR1
Early growth response protein 1

1

19

Small-scale

0.618

High

157902

NFYC
Nuclear transcription factor Y subunit gamma

2

5

High-throughput

0.606

High

157873

HD
Huntingtin

2

11

High-throughput

0.596

High

147206

TXND9
Thioredoxin domain-containing protein 9

1

1

High-throughput

0.573

High

157982

APBP2
Amyloid protein-binding protein 2

1

5

High-throughput

0.573

High

157855

PDIA1
Protein disulfide-isomerase

2

11

High-throughput

0.571

High

157875

CBX5
Chromobox protein homolog 5

1

20

Small-scale

0.561

High

158033

BOLA2
BolA-like protein 2

2

0

High-throughput

0.547

High

157859

CLUS
Clusterin

1

1

High-throughput

0.541

High

48034

E2F8
Transcription factor E2F8

1

11

High-throughput

0.515

High

124667

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

9

High-throughput

0.515

High

157837

PER1
Period circadian protein homolog 1

1

5

High-throughput

0.515

High

157841

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

14

High-throughput

0.515

High

157842

TADA3
Transcriptional adapter 3

1

5

High-throughput

0.515

High

157850

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.515

High

157852

A4
Amyloid-beta precursor protein

1

18

High-throughput

0.515

High

157853

FYN
Tyrosine-protein kinase Fyn

1

8

High-throughput

0.515

High

157856

VIME
Vimentin

1

11

High-throughput

0.515

High

157858

ANXA4
Annexin A4

1

4

High-throughput

0.515

High

157860

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

2

High-throughput

0.515

High

157861

ANXA8
Annexin A8

1

4

High-throughput

0.515

High

157863

GATA1
Erythroid transcription factor

1

15

High-throughput

0.515

High

157871

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

5

High-throughput

0.515

High

157872

PRS7
26S proteasome regulatory subunit 7

1

10

High-throughput

0.515

High

157874

VDAC2
Voltage-dependent anion-selective channel protein 2

1

6

High-throughput

0.515

High

157884

PKNX1
Homeobox protein PKNOX1

1

2

High-throughput

0.515

High

157887

VSX2
Visual system homeobox 2

1

3

High-throughput

0.515

High

157892

GABP1
GA-binding protein subunit beta-1

1

5

High-throughput

0.515

High

157895

TP53B
TP53-binding protein 1

1

5

High-throughput

0.515

High

157900

NDF1
Neurogenic differentiation factor 1

1

6

High-throughput

0.515

High

157903

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

1

4

High-throughput

0.515

High

157904

DPYS
Dihydropyrimidinase

1

3

High-throughput

0.515

High

157905

DELE1
DAP3-binding cell death enhancer 1

1

6

High-throughput

0.515

High

157907

KT33B
Keratin, type I cuticular Ha3-II

1

12

High-throughput

0.515

High

157909

STAT4
Signal transducer and activator of transcription 4

1

5

High-throughput

0.515

High

157915

TBRG1
Transforming growth factor beta regulator 1

1

7

High-throughput

0.515

High

157917

RHG29
Rho GTPase-activating protein 29

1

19

High-throughput

0.515

High

157921

FHL5
Four and a half LIM domains protein 5

1

15

High-throughput

0.515

High

157923

LEG9C
Galectin-9C

1

2

High-throughput

0.515

High

157924

OTU7B
OTU domain-containing protein 7B

1

12

High-throughput

0.515

High

157925

ESRP1
Epithelial splicing regulatory protein 1

1

8

High-throughput

0.515

High

157926

H3C
Histone H3.3C

1

11

High-throughput

0.515

High

157932

Q6PHZ7
NR2C2 protein

1

20

High-throughput

0.515

High

157946

TRI69
E3 ubiquitin-protein ligase TRIM69

1

19

High-throughput

0.515

High

157948

Q86WV8
TSC complex subunit 1

1

2

High-throughput

0.515

High

157949

CRLF3
Cytokine receptor-like factor 3

1

1

High-throughput

0.515

High

157955

PHC2
Polyhomeotic-like protein 2

1

8

High-throughput

0.515

High

157958

UBQLN
Ubiquilin-like protein

1

12

High-throughput

0.515

High

157969

VP37A
Vacuolar protein sorting-associated protein 37A

1

1

High-throughput

0.515

High

157970

CEP70
Centrosomal protein of 70 kDa

1

2

High-throughput

0.515

High

157971

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

1

High-throughput

0.515

High

157973

THAP3
THAP domain-containing protein 3

1

4

High-throughput

0.515

High

157979

ASB13
Ankyrin repeat and SOCS box protein 13

1

20

High-throughput

0.515

High

157981

LAR4B
La-related protein 4B

1

8

High-throughput

0.515

High

157983

H2A1C
Histone H2A type 1-C

1

2

High-throughput

0.515

High

157988

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.515

High

157989

ASB9
Ankyrin repeat and SOCS box protein 9

1

11

High-throughput

0.515

High

157991

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.515

High

157993

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.515

High

157994

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

4

High-throughput

0.515

High

158011

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.515

High

158014

AKAP9
A-kinase anchor protein 9

1

5

High-throughput

0.515

High

158015

DPYL5
Dihydropyrimidinase-related protein 5

1

3

High-throughput

0.515

High

158017

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

7

High-throughput

0.515

High

158019

LZTS2
Leucine zipper putative tumor suppressor 2

1

18

High-throughput

0.515

High

158023

PHF23
PHD finger protein 23

1

1

High-throughput

0.515

High

158028

OSBL6
Oxysterol-binding protein-related protein 6

1

1

High-throughput

0.515

High

158029

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

13

High-throughput

0.515

High

158032

UBQL3
Ubiquilin-3

1

10

High-throughput

0.515

High

158035

ZHX3
Zinc fingers and homeoboxes protein 3

1

20

High-throughput

0.515

High

158047

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

4

High-throughput

0.515

High

158051

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

4

High-throughput

0.515

High

158052

RGS17
Regulator of G-protein signaling 17

1

4

High-throughput

0.515

High

158053

KLHL3
Kelch-like protein 3

1

2

High-throughput

0.515

High

158056

DBNL
Drebrin-like protein

1

6

High-throughput

0.515

High

158057

CDC23
Cell division cycle protein 23 homolog

1

6

High-throughput

0.515

High

158060

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

2

High-throughput

0.515

High

158061

KLH20
Kelch-like protein 20

1

2

High-throughput

0.515

High

158063

ASB3
Ankyrin repeat and SOCS box protein 3

1

4

High-throughput

0.515

High

158065

MOFA1
MORF4 family-associated protein 1

1

2

High-throughput

0.515

High

157882

ATX1
Ataxin-1

1

9

High-throughput

0.508

High

157891

CBX1
Chromobox protein homolog 1

1

20

Small-scale

0.501

High

157896

CBX3
Chromobox protein homolog 3

1

20

Small-scale

0.501

High

157899

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.501

High

158064

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.494

High

50407

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.493

High

157835

TELT
Telethonin

1

0

High-throughput

0.493

High

157836

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.493

High

157840

TSN2
Tetraspanin-2

1

0

High-throughput

0.493

High

157845

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.493

High

157846

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.493

High

157847

DXO
Decapping and exoribonuclease protein

1

0

High-throughput

0.493

High

157849

ZWINT
ZW10 interactor

1

0

High-throughput

0.493

High

157851

MT2
Metallothionein-2

1

0

High-throughput

0.493

High

157854

CHLE
Cholinesterase

1

0

High-throughput

0.493

High

157862

VATB1
V-type proton ATPase subunit B, kidney isoform

1

0

High-throughput

0.493

High

157865

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.493

High

157876

RPGP1
Rap1 GTPase-activating protein 1

1

0

High-throughput

0.493

High

157878

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.493

High

157883

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.493

High

157888

STXB1
Syntaxin-binding protein 1

1

0

High-throughput

0.493

High

157890

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.493

High

157894

INCA1
Protein INCA1

1

0

High-throughput

0.493

High

157897

CENPR
Centromere protein R

1

0

High-throughput

0.493

High

157898

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.493

High

157906

BECN1
Beclin-1

1

0

High-throughput

0.493

High

157913

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.493

High

157919

PKHG4
Puratrophin-1

1

0

High-throughput

0.493

High

157922

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.493

High

157928

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.493

High

157934

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.493

High

157939

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

0

High-throughput

0.493

High

157942

CENPV
Centromere protein V

1

0

High-throughput

0.493

High

157943

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.493

High

157945

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.493

High

157947

TEN1L
CST complex subunit TEN1

1

0

High-throughput

0.493

High

157953

ARCH
Protein archease

1

0

High-throughput

0.493

High

157954

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.493

High

157961

PNKD
Probable hydrolase PNKD

1

0

High-throughput

0.493

High

157975

BRK1
Protein BRICK1

1

0

High-throughput

0.493

High

157976

CHMP7
Charged multivesicular body protein 7

1

0

High-throughput

0.493

High

157977

PRUN2
Protein prune homolog 2

1

0

High-throughput

0.493

High

157980

MYLIP
E3 ubiquitin-protein ligase MYLIP

1

0

High-throughput

0.493

High

157985

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.493

High

157995

SNF8
Vacuolar-sorting protein SNF8

1

0

High-throughput

0.493

High

157999

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.493

High

158002

BMF
Bcl-2-modifying factor

1

0

High-throughput

0.493

High

158003

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.493

High

158004

KAD8
Adenylate kinase 8

1

0

High-throughput

0.493

High

158005

ZN488
Zinc finger protein 488

1

0

High-throughput

0.493

High

158008

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.493

High

158012

TSNAX
Translin-associated protein X

1

0

High-throughput

0.493

High

158013

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.493

High

158020

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.493

High

158030

CK054
Ester hydrolase C11orf54

1

0

High-throughput

0.493

High

158031

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

0

High-throughput

0.493

High

158034

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.493

High

158039

CD209
CD209 antigen

1

0

High-throughput

0.493

High

158046

NSE4A
Non-structural maintenance of chromosomes element 4 homolog A

1

0

High-throughput

0.493

High

158050

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.493

High

158059

PADI3
Protein-arginine deiminase type-3

1

0

High-throughput

0.493

High

158062

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

0

High-throughput

0.493

High

157889

1433Z
14-3-3 protein zeta/delta

1

12

High-throughput

0.481

High

157893

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

46682

A0A384NQ31
Epididymis secretory sperm binding protein

1

3

High-throughput

0.470

High

60661

ODAD3
Outer dynein arm-docking complex subunit 3

1

5

High-throughput

0.470

High

81573

B7Z3E8
cDNA FLJ51208

1

20

High-throughput

0.470

High

111155

I6L9F6
NEFL protein

1

13

High-throughput

0.470

High

157843

STX11
Syntaxin-11

1

6

High-throughput

0.470

High

157857

IBP1
Insulin-like growth factor-binding protein 1

1

3

High-throughput

0.470

High

157866

IBP4
Insulin-like growth factor-binding protein 4

1

2

High-throughput

0.470

High

157867

CX7A1
Cytochrome c oxidase subunit 7A1, mitochondrial

1

1

High-throughput

0.470

High

157868

AOFB
Amine oxidase [flavin-containing] B

1

5

High-throughput

0.470

High

157877

RGR
RPE-retinal G protein-coupled receptor

1

1

High-throughput

0.470

High

157881

CRBA2
Beta-crystallin A2

1

1

High-throughput

0.470

High

157911

RCN1
Reticulocalbin-1

1

10

High-throughput

0.470

High

157930

KLC3
Kinesin light chain 3

1

6

High-throughput

0.470

High

157933

TTC33
Tetratricopeptide repeat protein 33

1

6

High-throughput

0.470

High

157937

AN13D
Ankyrin repeat domain-containing protein 13D

1

19

High-throughput

0.470

High

157950

TMTC1
Protein O-mannosyl-transferase TMTC1

1

7

High-throughput

0.470

High

157959

SPG16
Sperm-associated antigen 16 protein

1

9

High-throughput

0.470

High

157960

KT222
Keratin-like protein KRT222

1

15

High-throughput

0.470

High

157962

STX19
Syntaxin-19

1

6

High-throughput

0.470

High

157963

T11L2
T-complex protein 11-like protein 2

1

2

High-throughput

0.470

High

157968

Q8NE08
COL25A1 protein

1

2

High-throughput

0.470

High

157972

DDI1
Protein DDI1 homolog 1

1

12

High-throughput

0.470

High

157978

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.470

High

157996

MR1L1
MORF4 family-associated protein 1-like 1

1

2

High-throughput

0.470

High

157997

KAZD1
Kazal-type serine protease inhibitor domain-containing protein 1

1

4

High-throughput

0.470

High

158000

LOXL4
Lysyl oxidase homolog 4

1

2

High-throughput

0.470

High

158007

KLH32
Kelch-like protein 32

1

3

High-throughput

0.470

High

158021

WDR83
WD repeat domain-containing protein 83

1

15

High-throughput

0.470

High

158022

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

3

High-throughput

0.470

High

158025

KIFC3
Kinesin-like protein KIFC3

1

10

High-throughput

0.470

High

158038

CD248
Endosialin

1

19

High-throughput

0.470

High

158043

FGF21
Fibroblast growth factor 21

1

6

High-throughput

0.470

High

4629

A0A1B0GWI1
Coiled-coil domain containing 196

1

0

High-throughput

0.268

Low

49673

A1A512
KIAA0355 protein

1

0

High-throughput

0.268

Low

49925

F168B
Myelin-associated neurite-outgrowth inhibitor

1

0

High-throughput

0.268

Low

94675

F2Z2M7
Polypeptide N-acetylgalactosaminyltransferase 10

1

0

High-throughput

0.268

Low

157848

AQP8
Aquaporin-8

1

0

High-throughput

0.268

Low

157879

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.268

Low

157885

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

High-throughput

0.268

Low

157908

MESD
LRP chaperone MESD

1

0

High-throughput

0.268

Low

157910

LAP4A
Lysosomal-associated transmembrane protein 4A

1

0

High-throughput

0.268

Low

157916

F135B
Protein FAM135B

1

0

High-throughput

0.268

Low

157918

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.268

Low

157920

EFHC1
EF-hand domain-containing protein 1

1

0

High-throughput

0.268

Low

157927

PLB1
Phospholipase B1, membrane-associated

1

0

High-throughput

0.268

Low

157929

F117B
Protein FAM117B

1

0

High-throughput

0.268

Low

157931

TT23L
Tetratricopeptide repeat protein 23-like

1

0

High-throughput

0.268

Low

157935

CNST
Consortin

1

0

High-throughput

0.268

Low

157936

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.268

Low

157938

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.268

Low

157940

NUP54
Nucleoporin p54

1

0

High-throughput

0.268

Low

157941

SPT12
Spermatogenesis-associated protein 12

1

0

High-throughput

0.268

Low

157944

YRDC
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.268

Low

157951

K0825
Uncharacterized protein KIAA0825

1

0

High-throughput

0.268

Low

157952

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

0

High-throughput

0.268

Low

157956

Q8IXS7
SRGAP3 protein

1

0

High-throughput

0.268

Low

157957

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.268

Low

157964

MET27
Methyltransferase-like protein 27

1

0

High-throughput

0.268

Low

157965

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.268

Low

157967

ICA1L
Islet cell autoantigen 1-like protein

1

0

High-throughput

0.268

Low

157974

TM174
Transmembrane protein 174

1

0

High-throughput

0.268

Low

157984

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.268

Low

157986

TSACC
TSSK6-activating co-chaperone protein

1

0

High-throughput

0.268

Low

157990

REX1B
Required for excision 1-B domain-containing protein

1

0

High-throughput

0.268

Low

157992

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.268

Low

157998

GMPPA
Mannose-1-phosphate guanyltransferase alpha

1

0

High-throughput

0.268

Low

158006

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.268

Low

158016

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

0

High-throughput

0.268

Low

158018

Q9BR81
Protocadherin gamma subfamily C, 3

1

0

High-throughput

0.268

Low

158024

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.268

Low

158026

TEX12
Testis-expressed protein 12

1

0

High-throughput

0.268

Low

158036

GPN2
GPN-loop GTPase 2

1

0

High-throughput

0.268

Low

158040

AMBN
Ameloblastin

1

0

High-throughput

0.268

Low

158042

GKN1
Gastrokine-1

1

0

High-throughput

0.268

Low

158044

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.268

Low

158045

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.268

Low

158049

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.268

Low

158055

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.268

Low

157987

APH1A
Gamma-secretase subunit APH-1A

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024