HitPredict - High confidence protein-protein interactions

Protein: ROCK1
Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)

Gene: ROCK1
Organism: Mus musculus
Interactions: 9
UniProt ID: P70335

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001726 - ruffle
GO:0001837 - epithelial to mesenchymal transition
GO:0003383 - apical constriction
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
962875	RND3 Rho-related GTP-binding protein RhoE	1	20	Small-scale	0.724	High
1000195	CASP7 Caspase-7	1	4	Small-scale	0.501	High
1000200	SHRM3 Protein Shroom3	1	7	Small-scale	0.501	High
1000197	MYOME Myomegalin	1	9	High-throughput	0.489	High
108621	G3X9H5 Huntingtin	1	4	High-throughput	0.479	High
1000196	STING Stimulator of interferon genes protein	1	5	High-throughput	0.479	High
1000194	CASP3 Caspase-3	1	4	Small-scale	0.457	High
1000198	FTM Protein fantom	1	17	High-throughput	0.445	High
1000199	TRPM7 Transient receptor potential cation channel subfamily M member 7	1	2	Small-scale	0.445	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025