Protein: UTP4
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)

Gene: UTP4
Organism: Saccharomyces cerevisiae S288C
Interactions: 142
UniProt ID: Q06679

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0030490 - maturation of SSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

973682

UTP17
NET1-associated nuclear protein 1

7

20

Small-scale

0.963

High

979248

UTP15
U3 small nucleolar RNA-associated protein 15

7

19

Small-scale

0.963

High

772686

UTP18
U3 small nucleolar RNA-associated protein 18

7

3

Small-scale

0.963

High

635654

PWP2
Periodic tryptophan protein 2

7

17

Small-scale

0.962

High

767429

UTP7
U3 small nucleolar RNA-associated protein 7

5

19

Small-scale

0.925

High

985819

UTP21
U3 small nucleolar RNA-associated protein 21

5

18

Small-scale

0.915

High

987606

RRP9
Ribosomal RNA-processing protein 9

4

18

Small-scale

0.895

High

988641

UTP4
U3 small nucleolar RNA-associated protein 4

2

18

Small-scale

0.776

High

861037

UTP8
U3 small nucleolar RNA-associated protein 8

11

1

Small-scale

0.758

High

707147

DCA13
Protein SOF1

2

19

Small-scale

0.754

High

810927

MTR4
ATP-dependent RNA helicase DOB1

2

20

Small-scale

0.754

High

985425

UTP13
U3 small nucleolar RNA-associated protein 13

2

18

Small-scale

0.754

High

988656

UTP12
U3 small nucleolar RNA-associated protein 12

2

18

Small-scale

0.754

High

792596

UTP10
U3 small nucleolar RNA-associated protein 10

9

6

Small-scale

0.754

High

978639

UTP5
U3 small nucleolar RNA-associated protein 5

8

18

Small-scale

0.749

High

987662

NOC4
Nucleolar complex protein 4

8

7

Small-scale

0.748

High

756797

UTP9
U3 small nucleolar RNA-associated protein 9

7

1

Small-scale

0.746

High

748717

ENP1
Essential nuclear protein 1

8

2

Small-scale

0.743

High

634786

KRR1
KRR1 small subunit processome component

6

2

Small-scale

0.732

High

979039

DHR1
Probable ATP-dependent RNA helicase DHR1

6

8

Small-scale

0.726

High

860752

UTP22
U3 small nucleolar RNA-associated protein 22

5

3

Small-scale

0.716

High

988661

NOP58
Nucleolar protein 58

5

12

Small-scale

0.714

High

970476

UTP6
U3 small nucleolar RNA-associated protein 6

4

2

Small-scale

0.694

High

988650

UTP16
U3 small nucleolar RNA-associated protein 16

3

1

High-throughput

0.667

High

811568

MPP10
U3 small nucleolar RNA-associated protein MPP10

3

7

Small-scale

0.656

High

866624

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

3

3

Small-scale

0.656

High

982889

RRP5
rRNA biogenesis protein RRP5

3

11

High-throughput

0.656

High

987096

ESF1
Pre-rRNA-processing protein ESF1

3

1

High-throughput

0.654

High

630548

RRP7
Ribosomal RNA-processing protein 7

3

1

Small-scale

0.640

High

715990

UTP20
U3 small nucleolar RNA-associated protein 20

3

2

Small-scale

0.640

High

865426

CSL4
Exosome complex component CSL4

3

2

Small-scale

0.640

High

866064

NAT10
RNA cytidine acetyltransferase

3

3

Small-scale

0.640

High

979725

UTP14
U3 small nucleolar RNA-associated protein 14

3

7

Small-scale

0.640

High

988651

BMS1
Ribosome biogenesis protein BMS1

3

9

Small-scale

0.640

High

765987

DPO5
rDNA transcriptional regulator POL5

2

2

High-throughput

0.621

High

965045

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

8

High-throughput

0.618

High

766364

SNU13
13 kDa ribonucleoprotein-associated protein

1

8

Small-scale

0.618

High

865623

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

17

High-throughput

0.618

High

988648

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

2

Small-scale

0.618

High

775396

FAF1
Protein FAF1

2

1

Small-scale

0.611

High

988643

NOP6
Nucleolar protein 6

2

1

High-throughput

0.611

High

769577

SSB2
Ribosome-associated molecular chaperone SSB2

3

16

High-throughput

0.587

High

711080

UTP11
U3 small nucleolar RNA-associated protein 11

2

1

Small-scale

0.584

High

733609

RL1D1
Ribosome biogenesis protein UTP30

2

8

Small-scale

0.584

High

768124

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

1

Small-scale

0.584

High

799865

ROK1
ATP-dependent RNA helicase ROK1

2

11

Small-scale

0.584

High

811360

NOP9
Nucleolar protein 9

2

2

Small-scale

0.584

High

816914

NOL10
Ribosome biogenesis protein ENP2

2

4

Small-scale

0.584

High

864741

ESF2
Pre-rRNA-processing protein ESF2

2

2

Small-scale

0.584

High

986075

SGD1
Suppressor of glycerol defect protein 1

2

3

Small-scale

0.584

High

986756

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

1

Small-scale

0.584

High

988475

BFR2
Protein BFR2

2

3

Small-scale

0.584

High

988644

CMS1
Protein CMS1

2

1

Small-scale

0.584

High

988645

RCL1
RNA 3'-terminal phosphate cyclase-like protein

2

2

Small-scale

0.584

High

988654

SAS10
Something about silencing protein 10

2

3

Small-scale

0.584

High

988655

RRP6
Exosome complex exonuclease RRP6

2

8

High-throughput

0.584

High

988662

RRP12
Ribosomal RNA-processing protein 12

2

3

Small-scale

0.584

High

988665

NOP14
Nucleolar complex protein 14

2

4

Small-scale

0.584

High

988666

PNO1
Pre-rRNA-processing protein PNO1

2

1

Small-scale

0.584

High

985904

MRD1
Multiple RNA-binding domain-containing protein 1

2

6

Small-scale

0.571

High

512876

SSB1
Ribosome-associated molecular chaperone SSB1

2

16

High-throughput

0.565

High

820191

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.553

High

860388

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.553

High

704432

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

4

High-throughput

0.536

High

471274

RS22A
Small ribosomal subunit protein uS8A

2

4

High-throughput

0.533

High

492559

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.489

High

629587

CDC10
Cell division control protein 10

1

10

High-throughput

0.489

High

643699

SYLC
Leucine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.489

High

864614

BRE5
UBP3-associated protein BRE5

1

7

High-throughput

0.489

High

407342

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.479

High

413726

RS14A
Small ribosomal subunit protein uS11A

1

6

High-throughput

0.479

High

549511

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

9

High-throughput

0.479

High

584804

CSK22
Casein kinase II subunit alpha'

1

12

Small-scale

0.479

High

606769

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

630269

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

645672

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

688447

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

700104

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

7

High-throughput

0.479

High

700643

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

706506

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

753186

DBP8
ATP-dependent RNA helicase DBP8

1

15

High-throughput

0.479

High

754200

CIC1
Proteasome-interacting protein CIC1

1

8

High-throughput

0.479

High

755003

RRP4
Exosome complex component RRP4

1

4

High-throughput

0.479

High

755207

LRP1
Exosome complex protein LRP1

1

1

High-throughput

0.479

High

758478

RRP8
25S rRNA

1

3

High-throughput

0.479

High

774287

RRT14
Regulator of rDNA transcription protein 14

1

1

High-throughput

0.479

High

774758

UTP25
U3 small nucleolar RNA-associated protein 25

1

1

High-throughput

0.479

High

791281

KRI1
Protein KRI1

1

3

Small-scale

0.479

High

809594

RRP41
Exosome complex component SKI6

1

12

High-throughput

0.479

High

816980

MTR3
Exosome complex component MTR3

1

1

High-throughput

0.479

High

859439

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

7

Small-scale

0.479

High

860817

RRP46
Exosome complex component RRP46

1

12

High-throughput

0.479

High

967780

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

975842

TOM1
E3 ubiquitin-protein ligase TOM1

1

8

High-throughput

0.479

High

976869

HAS1
ATP-dependent RNA helicase HAS1

1

20

High-throughput

0.479

High

979414

BUD22
Bud site selection protein 22

1

1

Small-scale

0.479

High

983775

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

984315

RRP45
Exosome complex component RRP45

1

8

High-throughput

0.479

High

988646

RRP44
Exosome complex exonuclease DIS3

1

3

High-throughput

0.479

High

988647

RRP40
Exosome complex component RRP40

1

1

High-throughput

0.479

High

988653

FCF2
rRNA-processing protein FCF2

1

2

High-throughput

0.479

High

988657

RRP42
Exosome complex component RRP42

1

8

High-throughput

0.479

High

988658

UTP23
rRNA-processing protein UTP23

1

2

Small-scale

0.479

High

988659

NOP56
Nucleolar protein 56

1

12

High-throughput

0.479

High

988660

RRP36
rRNA biogenesis protein RRP36

1

1

High-throughput

0.479

High

988663

EFG1P
rRNA-processing protein EFG1

1

1

High-throughput

0.479

High

755117

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.458

High

743699

HMT1
Protein arginine N-methyltransferase 1

1

7

Small-scale

0.457

High

733946

RPF2
Ribosome biogenesis protein RPF2

1

2

High-throughput

0.445

High

403032

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

4

Small-scale

0.437

High

597348

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.437

High

663428

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

704242

BUD2
Inhibitory regulator protein BUD2/CLA2

1

7

Small-scale

0.437

High

762589

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

959880

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.437

High

977476

BUL2
Ubiquitin ligase-binding protein BUL2

1

1

Small-scale

0.437

High

988642

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

988649

SGO1
Shugoshin

1

1

High-throughput

0.437

High

988652

NEW1
[NU+] prion formation protein 1

1

2

Small-scale

0.437

High

988664

RS22B
Small ribosomal subunit protein uS8B

1

4

High-throughput

0.437

High

424732

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.407

High

478552

HSP77
Import motor subunit, mitochondrial

1

18

High-throughput

0.407

High

495066

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.407

High

544478

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.407

High

629058

SCJ1
DnaJ-related protein SCJ1

1

7

High-throughput

0.407

High

633608

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.407

High

681024

HS104
Heat shock protein 104

1

3

High-throughput

0.407

High

695613

HSP7F
Heat shock protein homolog SSE1

1

18

High-throughput

0.407

High

705702

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

715860

MDJ1
DnaJ homolog 1, mitochondrial

1

7

High-throughput

0.407

High

748470

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

14

High-throughput

0.407

High

760695

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.407

High

761325

CAJ1
Protein CAJ1

1

7

High-throughput

0.407

High

764783

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.407

High

766230

HSP7E
Heat shock protein SSC3, mitochondrial

1

18

High-throughput

0.407

High

798024

ERJ5
ER-localized J domain-containing protein 5

1

8

High-throughput

0.407

High

817297

HLJ1
Protein HLJ1

1

3

High-throughput

0.407

High

988584

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

10

High-throughput

0.407

High

419578

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.279

Low

533953

INO4
Protein INO4

1

0

High-throughput

0.279

Low

864439

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024