HitPredict - High confidence protein-protein interactions

Protein: IGF1R
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]

Gene: IGF1R
Organism: Mus musculus
Interactions: 8
UniProt ID: Q60751

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004713 - protein tyrosine kinase activity
GO:0005010 - insulin-like growth factor receptor activity
GO:0005198 - structural molecule activity
GO:0005520 - insulin-like growth factor binding

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1221439	GRB10 Growth factor receptor-bound protein 10	3	20	Small-scale	0.812	High
772558	IRS1 Insulin receptor substrate 1	1	20	Small-scale	0.647	High
1221440	SNX9 Sorting nexin-9	1	20	Small-scale	0.618	High
662970	MDM2 E3 ubiquitin-protein ligase Mdm2	1	3	Small-scale	0.479	High
999905	PACR Pituitary adenylate cyclase-activating polypeptide type I receptor	1	13	Small-scale	0.479	High
1221441	PODO Podocin	1	14	Small-scale	0.479	High
609539	PCNA Proliferating cell nuclear antigen	1	2	Small-scale	0.437	High
108673	G3X9H5 Huntingtin	1	0	High-throughput	0.249	Low

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Last updated: 11Aug2025