Protein: FBX25
F-box only protein 25

Gene: FBX25, FBXO25
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q8TCJ0

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003779 - actin binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

929003

SKP1
S-phase kinase-associated protein 1

6

3

Small-scale

0.733

High

1041106

CUL1
Cullin-1

4

4

Small-scale

0.694

High

993041

RHG01
Rho GTPase-activating protein 1

3

0

High-throughput

0.638

High

1253589

UB2E3
Ubiquitin-conjugating enzyme E2 E3

2

1

High-throughput

0.611

High

584263

ELK1
ETS domain-containing protein Elk-1

2

0

Small-scale

0.598

High

432090

HS90A
Heat shock protein HSP 90-alpha

2

2

High-throughput

0.584

High

891914

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.581

High

874143

PSMD4
26S proteasome non-ATPase regulatory subunit 4

2

0

Small-scale

0.569

High

1202006

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.536

High

1015814

SCRN1
Secernin-1

1

0

High-throughput

0.513

High

124445

HIP1
Huntingtin-interacting protein 1

1

8

Small-scale

0.501

High

213901

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

1

Small-scale

0.501

High

331048

PAK4
Serine/threonine-protein kinase PAK 4

1

1

Small-scale

0.501

High

409171

K2C8
Keratin, type II cytoskeletal 8

1

2

Small-scale

0.501

High

557206

PGFRA
Platelet-derived growth factor receptor alpha

1

2

Small-scale

0.501

High

626656

ARBK1
Beta-adrenergic receptor kinase 1

1

1

Small-scale

0.501

High

729670

VGFR2
Vascular endothelial growth factor receptor 2

1

1

Small-scale

0.501

High

807450

RS10
Small ribosomal subunit protein eS10

1

1

Small-scale

0.501

High

841818

CDK9
Cyclin-dependent kinase 9

1

2

Small-scale

0.501

High

858113

NKX25
Homeobox protein Nkx-2.5

1

1

Small-scale

0.501

High

895855

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

1

Small-scale

0.501

High

961556

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

1

Small-scale

0.501

High

1016497

TWF1
Twinfilin-1

1

3

Small-scale

0.501

High

1021765

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

1

Small-scale

0.501

High

1124566

ODFP2
Outer dense fiber protein 2

1

10

Small-scale

0.501

High

1238749

WSDU1
WD repeat, SAM and U-box domain-containing protein 1

1

1

Small-scale

0.501

High

1253595

TBX5
T-box transcription factor TBX5

1

2

Small-scale

0.501

High

1253602

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

Small-scale

0.501

High

1253612

DYRK4
Dual specificity tyrosine-phosphorylation-regulated kinase 4

1

1

Small-scale

0.501

High

1253618

LMCD1
LIM and cysteine-rich domains protein 1

1

2

Small-scale

0.501

High

1253621

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

Small-scale

0.501

High

1253622

UBQL2
Ubiquilin-2

1

4

Small-scale

0.501

High

1253626

UBQL1
Ubiquilin-1

1

4

Small-scale

0.501

High

1253631

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

Small-scale

0.501

High

217826

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.481

High

1253593

CK5P2
CDK5 regulatory subunit-associated protein 2

1

9

High-throughput

0.481

High

229964

NUAK1
NUAK family SNF1-like kinase 1

1

0

Small-scale

0.480

High

237273

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

Small-scale

0.480

High

278846

DNJC8
DnaJ homolog subfamily C member 8

1

0

Small-scale

0.480

High

338727

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.480

High

422550

CENPB
Major centromere autoantigen B

1

0

Small-scale

0.480

High

566439

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.480

High

636505

DNJB2
DnaJ homolog subfamily B member 2

1

0

Small-scale

0.480

High

724448

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.480

High

724553

IRS1
Insulin receptor substrate 1

1

0

Small-scale

0.480

High

959958

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.480

High

996412

PPID
Peptidyl-prolyl cis-trans isomerase D

1

0

Small-scale

0.480

High

1030373

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

Small-scale

0.480

High

1131363

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

Small-scale

0.480

High

1204676

DDX42
ATP-dependent RNA helicase DDX42

1

0

Small-scale

0.480

High

1218132

APLF
Aprataxin and PNK-like factor

1

0

Small-scale

0.480

High

1223849

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

Small-scale

0.480

High

1230235

EID3
EP300-interacting inhibitor of differentiation 3

1

0

Small-scale

0.480

High

1237611

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

1

0

Small-scale

0.480

High

1240880

SERB1
SERPINE1 mRNA-binding protein 1

1

0

Small-scale

0.480

High

1253584

TCP1L
T-complex protein 10A homolog 1

1

0

Small-scale

0.480

High

1253586

TRUB1
Pseudouridylate synthase TRUB1

1

0

Small-scale

0.480

High

1253603

TCAL2
Transcription elongation factor A protein-like 2

1

0

Small-scale

0.480

High

1253607

ILRUN
Protein ILRUN

1

0

Small-scale

0.480

High

1253610

SYTL2
Synaptotagmin-like protein 2

1

0

Small-scale

0.480

High

1253615

ING3
Inhibitor of growth protein 3

1

0

Small-scale

0.480

High

1253617

MAT2B
Methionine adenosyltransferase 2 subunit beta

1

0

Small-scale

0.480

High

1253624

PADI4
Protein-arginine deiminase type-4

1

0

Small-scale

0.480

High

1253633

RBM8A
RNA-binding protein 8A

1

0

Small-scale

0.480

High

1253634

EPN1
Epsin-1

1

0

Small-scale

0.480

High

117772

MYO1C
Unconventional myosin-Ic

1

10

High-throughput

0.479

High

121819

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

4

High-throughput

0.479

High

153735

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.479

High

159600

ML12B
Myosin regulatory light chain 12B

1

2

High-throughput

0.479

High

163035

XPO1
Exportin-1

1

1

High-throughput

0.479

High

198675

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.479

High

207970

XPOT
Exportin-T

1

1

High-throughput

0.479

High

214623

MYO1B
Unconventional myosin-Ib

1

10

High-throughput

0.479

High

297383

MYO1D
Unconventional myosin-Id

1

11

High-throughput

0.479

High

363855

ALBU
Albumin

1

1

High-throughput

0.479

High

381249

TBB4A
Tubulin beta-4A chain

1

8

High-throughput

0.479

High

414006

GELS
Gelsolin

1

1

High-throughput

0.479

High

415422

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

417368

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

438380

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

443678

VIME
Vimentin

1

5

High-throughput

0.479

High

502350

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

504445

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

518723

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

531220

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

535488

GFAP
Glial fibrillary acidic protein

1

5

High-throughput

0.479

High

541393

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

573025

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

618133

COF1
Cofilin-1

1

3

High-throughput

0.479

High

624361

MYL9
Myosin regulatory light polypeptide 9

1

2

High-throughput

0.479

High

627310

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.479

High

653326

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.479

High

724928

MYH9
Myosin-9

1

8

High-throughput

0.479

High

725204

MYH10
Myosin-10

1

8

High-throughput

0.479

High

728494

MYH11
Myosin-11

1

8

High-throughput

0.479

High

751731

GRP75
Stress-70 protein, mitochondrial

1

5

High-throughput

0.479

High

770946

TCPZ
T-complex protein 1 subunit zeta

1

3

High-throughput

0.479

High

842970

TCPQ
T-complex protein 1 subunit theta

1

5

High-throughput

0.479

High

843470

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

2

High-throughput

0.479

High

855150

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

1

High-throughput

0.479

High

855516

MSH6
DNA mismatch repair protein Msh6

1

1

High-throughput

0.479

High

863499

COPA
Coatomer subunit alpha

1

1

High-throughput

0.479

High

871691

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.479

High

874548

XPO2
Exportin-2

1

2

High-throughput

0.479

High

906884

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.479

High

907104

PRS8
26S proteasome regulatory subunit 8

1

3

High-throughput

0.479

High

921354

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

Small-scale

0.479

High

924087

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.479

High

929934

ACTG
Actin, cytoplasmic 2

1

6

High-throughput

0.479

High

933535

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.479

High

933906

TBB4B
Tubulin beta-4B chain

1

8

High-throughput

0.479

High

966738

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

1

High-throughput

0.479

High

984401

EF1A2
Elongation factor 1-alpha 2

1

1

High-throughput

0.479

High

1023205

FLII
Protein flightless-1 homolog

1

1

High-throughput

0.479

High

1027731

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1034940

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1037313

TBB3
Tubulin beta-3 chain

1

8

High-throughput

0.479

High

1046521

TBB2A
Tubulin beta-2A chain

1

8

High-throughput

0.479

High

1075940

PCH2
Pachytene checkpoint protein 2 homolog

1

4

High-throughput

0.479

High

1085006

DREB
Drebrin

1

1

High-throughput

0.479

High

1122453

ACTBL
Beta-actin-like protein 2

1

6

High-throughput

0.479

High

1148937

CYTSA
Cytospin-A

1

8

High-throughput

0.479

High

1189778

MYH14
Myosin-14

1

8

High-throughput

0.479

High

1253588

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1253596

DNJC7
DnaJ homolog subfamily C member 7

1

3

High-throughput

0.479

High

1253597

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.479

High

1253599

TBA1C
Tubulin alpha-1C chain

1

4

High-throughput

0.479

High

1253601

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

6

High-throughput

0.479

High

1253604

UN45A
Protein unc-45 homolog A

1

4

High-throughput

0.479

High

1253605

TBB1
Tubulin beta-1 chain

1

11

High-throughput

0.479

High

1253620

MYO1A
Unconventional myosin-Ia

1

10

High-throughput

0.479

High

1253625

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

1253627

SMC3
Structural maintenance of chromosomes protein 3

1

4

High-throughput

0.479

High

1253628

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

1253629

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

1253632

MYO5A
Unconventional myosin-Va

1

6

High-throughput

0.479

High

111483

J9JIF5
CXXC-type zinc finger protein 4

1

0

High-throughput

0.460

High

1199939

GTD2A
General transcription factor II-I repeat domain-containing protein 2A

1

0

High-throughput

0.460

High

73163

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

0

High-throughput

0.458

High

161410

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.458

High

418484

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

540865

PO2F1
POU domain, class 2, transcription factor 1

1

0

Small-scale

0.458

High

582401

NUCL
Nucleolin

1

0

High-throughput

0.458

High

671289

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.458

High

681533

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.458

High

708988

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.458

High

789890

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

809372

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.458

High

876854

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.458

High

878547

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.458

High

880143

SYMC
Methionine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

907415

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

941666

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.458

High

1087282

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.458

High

1253590

SH3K1
SH3 domain-containing kinase-binding protein 1

1

0

High-throughput

0.458

High

1253592

PAWR
PRKC apoptosis WT1 regulator protein

1

0

High-throughput

0.458

High

1253616

TMOD3
Tropomodulin-3

1

0

High-throughput

0.458

High

1253623

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

1028464

KGP2
cGMP-dependent protein kinase 2

1

2

Small-scale

0.457

High

1253591

HMCES
Abasic site processing protein HMCES

1

1

Small-scale

0.457

High

1253594

STAC
SH3 and cysteine-rich domain-containing protein

1

2

Small-scale

0.457

High

1253606

RABE2
Rab GTPase-binding effector protein 2

1

9

Small-scale

0.457

High

1253608

RPAP3
RNA polymerase II-associated protein 3

1

3

Small-scale

0.457

High

197361

SERA
D-3-phosphoglycerate dehydrogenase

1

1

High-throughput

0.437

High

312340

IPO7
Importin-7

1

2

High-throughput

0.437

High

393291

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.437

High

514048

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.437

High

561634

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

2

High-throughput

0.437

High

573386

TCPA
T-complex protein 1 subunit alpha

1

4

High-throughput

0.437

High

637001

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.437

High

821328

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.437

High

843301

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.437

High

1062847

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

2

High-throughput

0.437

High

1135276

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.437

High

1162515

Q6PK50
Heat shock protein HSP 90-beta

1

3

High-throughput

0.437

High

1167387

MPRIP
Myosin phosphatase Rho-interacting protein

1

9

High-throughput

0.437

High

1234851

TTC9C
Tetratricopeptide repeat protein 9C

1

3

High-throughput

0.437

High

1253613

ATD3A
ATPase family AAA domain-containing protein 3A

1

3

High-throughput

0.437

High

1253619

RAI14
Ankycorbin

1

1

High-throughput

0.437

High

1253614

PNPO
Pyridoxine-5'-phosphate oxidase

3

0

High-throughput

0.347

High

835202

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.268

Low

152189

TMG1
Transmembrane gamma-carboxyglutamic acid protein 1

1

0

Small-scale

0.261

Low

152972

RIOK3
Serine/threonine-protein kinase RIO3

1

0

Small-scale

0.261

Low

208276

DCX
Neuronal migration protein doublecortin

1

0

Small-scale

0.261

Low

674481

UFO
Tyrosine-protein kinase receptor UFO

1

0

Small-scale

0.261

Low

850754

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

0

Small-scale

0.261

Low

1012459

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

Small-scale

0.261

Low

1156336

JHY
Jhy protein homolog

1

0

Small-scale

0.261

Low

1217315

PRR15
Proline-rich protein 15

1

0

Small-scale

0.261

Low

1245098

TNIP2
TNFAIP3-interacting protein 2

1

0

Small-scale

0.261

Low

1252032

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.261

Low

1253101

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

0

Small-scale

0.261

Low

1253585

RHBL4
Rhomboid-related protein 4

1

0

Small-scale

0.261

Low

1253600

CG050
Uncharacterized protein C7orf50

1

0

Small-scale

0.261

Low

1253609

IL21
Interleukin-21

1

0

Small-scale

0.261

Low

1253611

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

Small-scale

0.261

Low

1253630

TMA7
Translation machinery-associated protein 7

1

0

Small-scale

0.261

Low

118374

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.249

Low

390394

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

391040

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1253587

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.249

Low

1253598

Q9BPW0
Serine/threonine-protein phosphatase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024